HOME >> BIOLOGY >> NEWS
Moderate lifetime reductions in LDL cholesterol dramatically reduce risk of heart disease

A new genetic analysis of more than 12,000 individuals has found that a decrease in low density lipoprotein (LDL) cholesterol, of as little as 15 percent, sustained over the long term can dramatically reduce the risk of coronary heart disease. The reduction in LDL observed in this study can easily be achieved with a low dose of cholesterol-lowering drugs called statins.

The analysis, which included both white and black populations, indicates that low levels of LDL cholesterol are protective even for people who have other significant risk factors for heart disease.

"What this study shows is that low plasma levels of LDL had a dramatic effect on the incidence of coronary events over a 15-year period. This is in individuals living in the same place, subjected to the same stresses, and having a similar prevalence of the major coronary risk factors hypertension, diabetes, and smoking and really high levels of those risk factors," said Helen H. Hobbs, a Howard Hughes Medical Institute investigator at the University of Texas Southwestern Medical Center in Dallas.

Hobbs led the study, in collaboration with colleagues at the University of Texas Southwestern, the University of Texas Health Science Center in Houston, and the University of Mississippi Medical Center. The work, which suggests that susceptible individuals may benefit from earlier medical intervention, was partially funded by the Donald W. Reynolds Foundation and is published in the March 23, 2006, issue of the New England Journal of Medicine.

In an accompanying editorial in the same issue of the journal, Alan R. Tall, a professor of medicine at Columbia University, wrote that the findings "suggest that a one percent reduction in LDL cholesterol level over a lifetime translates into a reduction of more than two percent in the risk of cardiovascular disease."

LDL cholesterol, a waxy substance that can build up and clog arteries, is an essential fact
'"/>

Contact: Jennifer Michalowski
michalow@hhmi.org
301-215-8576
Howard Hughes Medical Institute
22-Mar-2006


Page: 1 2 3 4 5

Related biology news :

1. Moderate drinking may help older women live longer
2. Moderate drinking may boost memory, study suggests
3. Moderate exercise may delay congestive heart failure, CU-Boulder study suggests
4. Moderate alcohol consumption enhances the formation of new nerve cells
5. Moderate aerobic exercise improves cardiovascular and nervous system function in HIV+
6. Delayed breeding is not necessarily costly to lifetime reproductive success
7. Making memories that last a lifetime
8. Scripps marine research physiologist pioneer to receive lifetime achievement award
9. Shorter tuberculosis therapies could lead to substantial reductions in cases and deaths
10. Tick-related disease thrives on cholesterol, study suggests
11. High cholesterol diets modify gene expression in atherosclerosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: