HOME >> BIOLOGY >> NEWS
Molecular rendezvous caught on camera

This release is also available in German.

The body is an almost perfect machine. For it to function properly, each individual component, that is each molecule, must reliably fulfill its specific function. Each molecule must thus "recognize" other molecules and work with them. A team of researchers from the Max Planck Institute for Solid State Research in Stuttgart, the Fraunhofer Institute in Freiburg, and King's College in London, has now successfully filmed pairs of molecules during the recognition process. As reported to the journal Angewandte Chemie, the shapes of the molecules change to accommodate each other.

Like humans, molecules also "greet" each other with a kind of "handshake". Anyone who has tried to shake someone's right hand with his or her own left will have had a little trouble: the right and left hands do not fit together. In the same way, some molecules that exist in both a right-handed (D) and left-handed (L) configuration can tell if others they encounter are the D or L form.

Magali Lingenfelder and colleagues at the Max Planck Institute for Solid State Research have now been able to use scanning tunneling microscopy to take a series of pictures that follow in detail the "encounters" of diphenylalanine molecules adsorbed onto a substrate. (Diphenylalanine is the central structural unit within polypeptide fibers found in the brains of Alzheimer's patients.) The "film sequences" reveal that only molecules with the same chirality (handedness) readily aggregate into pairs and chains.

Just as in a handshake, it is not enough that the right hands hold each other. To grip each other firmly, the two hands must adapt to fit their shapes together. Molecules do the same: close examination of the "film", in conjunction with theoretical calculations by researchers from King's College, prove that this type of dynamic accommodation of shape also o
'"/>

Contact: Magal Lingenfelder
m.lingenfelder@fkf.mpg.de
49-711-689-1620
John Wiley & Sons, Inc.
2-May-2007


Page: 1 2

Related biology news :

1. Molecular detectors may refine cancer treatment
2. Story ideas from Molecular & Cellular Proteomics
3. 2007 Image of the Year: Molecular imaging relates human brain chemistry to aggressive behavior
4. Molecular motors may speed nutrient processing
5. Molecular tools make the cut
6. Genomatix and Molecular Connections form strategic partnership
7. Molecular motors and brakes work together in cells
8. Molecular link between inflammation and cancer discovered
9. Molecular on/off switch controls immune defenses against viruses
10. Molecular marker on stem cells aids research, perhaps therapies
11. Molecular mechanism provides intra-cellular traffic signal

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/5/2017)... 5, 2017  The Allen Institute for Cell Science ... a one-of-a-kind portal and dynamic digital window into the ... the first application of deep learning to create predictive ... lines and a growing suite of powerful tools. The ... and future publicly available resources created and shared by ...
(Date:4/4/2017)...   EyeLock LLC , a leader of iris-based ... Patent and Trademark Office (USPTO) has issued U.S. Patent ... an iris image with a face image acquired in ... 45 th issued patent. "The ... the multi-modal biometric capabilities that have recently come to ...
Breaking Biology News(10 mins):
(Date:7/20/2017)... Massachusetts (PRWEB) , ... July 20, 2017 , ... ... a multi-part seminar on digital pathology and artificial intelligence Tuesday, July 25, during ... Dr. Alexander Baras from Johns Hopkins Medicine. , Baras, Associate Director of ...
(Date:7/18/2017)... ... July 18, 2017 , ... Nanomedical Diagnostics, a cutting-edge ... the launch of a new NTA biosensor chip for use with its label-free ... kinetics of polyhistidine-tagged (His-tagged) molecules quickly and reliably. , “Recombinant proteins are ...
(Date:7/18/2017)... ... July 18, 2017 , ... Blood centers traditionally see a dangerous ... Nationally, summer is a struggle for community blood centers as high schools are out ... Chamber of Commerce is teaming up with the South Texas Blood & ...
(Date:7/17/2017)... ... ... The Academy of Model Aeronautics (AMA) will host Aviation Adventure Day on ... from 9 a.m. to 2 p.m. at the International Aeromodeling Center in Muncie, Indiana. ... Day will be packed with entertaining activities for the entire family. Attendees will learn ...
Breaking Biology Technology:
Cached News: