HOME >> BIOLOGY >> NEWS
Molecule that usually protects infection-fighting cells may cause plaque deposits inside arteries

adually thicken into a plaque. As plaque grows, it narrows the artery more and more. When the plaque ruptures, blood clots form that can block the artery entirely.

Low-density lipoprotein is transported inside arteries by macrophages, which engulf the cholesterol through a process called oxidation. Macrophages produce pro-inflammatory substances, which cause a secondary effect, encouraging other cells to accumulate and worsen plaque buildup in arteries.

"The oxidized lipids are cleared out by macrophage cells, but the lipids themselves are very toxic to cells and promote apoptosis (cell death)," Dr. Miyazaki said. "Therefore AIM production is a self-defense mechanism for macrophage cells, but interestingly, is in turn detrimental for the body."

Atherosclerosis is a contributing factor to a number of cardiovascular diseases the No. 1 cause of death among people in the United States. It is also highly associated with other risk factors such as smoking, obesity and diets high in fat and cholesterol.


'"/>

Contact: Katherine Morales
katherine.morales@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
15-Mar-2005


Page: 1 2

Related biology news :

1. Molecule blocks gene, sheds light on liver cancer
2. Molecule that destroys bone also protects it, new research shows
3. Howard C. Berg honored with Outstanding Investigator in Single Molecule Biology Award
4. Molecule discovered to be key to pain sensitivity
5. Molecules in blood foretell development of preeclampsia
6. Molecule by molecule, new assay shows real-time gene activity
7. Molecule does more than slice and dice RNA
8. Molecule links Down syndrome to Alzheimers
9. Molecule crucial for processing non-coding RNA identified
10. Molecule on immune cells linked to sexual transmission of HIV
11. Molecule that helps DNA replicate may make good target for cancer therapy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/11/2017)... Jan. 11, 2017 Intoxalock, a leading ignition ... release of its patent-pending calibration device. With this new ... calibrations, securely upload data logs and process repairs at ... "Fighting drunk driving through the application of ... at large, but also for the customer who can ...
(Date:1/6/2017)... Calif. , Jan. 6, 2017  Privately-held ... safety studies in healthy volunteers of a novel ... to treat acute pancreatitis. Acute ... typically a mild disorder, but can be very ... failure and sepsis, where extended hospital stays, time ...
(Date:1/6/2017)... 2017  Delta ID Inc., a leader in consumer-grade ... automotive at CES® 2017. Delta ID has collaborated with ... the use of iris scanning as a secure, reliable ... in a car, and as a way to elevate ... Delta ID and Gentex will demonstrate (booth #7326 ...
Breaking Biology News(10 mins):
(Date:1/12/2017)... The Energy and Resources Institute ... producing mycorrhizae. The Centre for Mycorrhizal Research at TERI ... and developed a technology that eventually produces mycorrhizae based ... ... The TERI facility has a production capacity of over ...
(Date:1/12/2017)... 12, 2017 The report "Direct-Fed Microbials Market by Type (Lactic Acid ... Liquid), and Region - Global Forecast to 2022", published by MarketsandMarkets, the global ... projected to reach USD 1,399.6 Million by 2022, at a CAGR of 6.96% ... ... MarketsandMarkets Logo ...
(Date:1/11/2017)... ... January 11, 2017 , ... Ovation Fertility™ Genetics ... reliable preimplantation genetic screening (PGS). , “Our genetics and IVF teams are recognized ... Genetics Scientific Director Amy Jones, M.S., ELD (ABB) , who has worked ...
(Date:1/11/2017)... 11, 2017  Brian Mehling, M.D., world-renowned stem cell ... Horizon International (BHI), will be attending the 47th Annual ... from January 17-20, 2017. This will be Dr. ... The theme of this year,s forum is Responsive and ... will address strategies for fostering greater social inclusion and ...
Breaking Biology Technology:
Cached News: