HOME >> BIOLOGY >> NEWS
Mouse, frog and bird put Snail and Slug to different uses

Bar Harbor, Maine--With names like Snail and Slug, you might expect genes belonging to the category known as the Snail family to be associated with some steady, slow-moving biological progression. Instead, these genes help direct the dynamic, fast-paced race of early embryonic development, when cells are dividing, migrating around the body and differentiating into the millions, even trillions, of specialized cells that constitute a mature organism.

Snail family genes are present in vertebrates and have counterparts in invertebrates such as the fruit fly Drosophila. To biologists, this means that these genes are "well conserved across species"--in other words, diverse species retained them as they evolved. So it's reasonable to expect that their function would be the same among all vertebrates: mice as well as frogs and birds, for instance.

In a paper just released in the Proceedings of the National Academy of Sciences, two Jackson Laboratory scientists have demonstrated both a confirmation of the consistent role of Snail genes in vertebrates, and a surprising exception.

Dr. Thomas Gridley and Dr. Steven Murray showed that Snail family genes operate consistently in mice and birds in controlling the acquisition of differences between the two sides of the body. While the body plan of all vertebrates is overtly symmetric on both body sides, most internal organs exhibit an asymmetric distribution. For example, in mammals the heart is located on the left side of the body while the liver is on the right. Gridley and Murray found that, similarly to what has been described for birds, the Snail gene controls acquisition of these asymmetric body differences in mice.

On the other hand, Gridley and Murray found that Snail family gene function relating to neural crest cells is different in mice. Neural crest cells are developmental cells that form at the border of the embryonic neural plate (a structure that later develops into the spina
'"/>

Contact: Mark Wanner
mark.wanner@jax.org
207-288-6051
Jackson Laboratory
26-Jun-2006


Page: 1 2

Related biology news :

1. Research: Snails were overlooked contributors to marsh destruction
2. A sensory organ, not the brain, differentiates male and female behavior in some mammals
3. New clue why MS affects African-Americans differently than Caucasians
4. Marine phytoplankton changes form to protect itself from different predators
5. Mice, men make livers differently
6. Palaus coral reefs show differential habitat recovery following the 1998 bleaching event
7. Hearts of male and female rainbow trout are different
8. Freeze! Scientists film proteins at work by freezing them at different states
9. NYU scientists identify how development of different species uses same genes with distinct features
10. Making daughters different -- how immune cells take divergent paths when fighting infections
11. UT-Houston scientists develop new procedure to differentiate human embryonic stem cells

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)...  The Allen Institute for Cell Science today announces ... portal and dynamic digital window into the human cell. ... application of deep learning to create predictive models of ... a growing suite of powerful tools. The Allen Cell ... publicly available resources created and shared by the Allen ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
(Date:3/29/2017)... CHICAGO , March 29, 2017  higi, the ... ecosystem in North America , today ... Partners and the acquisition of EveryMove. The new investment ... extensive set of tools to transform population health activities ... and lifestyle data. higi collects and secures ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... ... October 09, 2017 , ... The award-winning American Farmer television ... quarter 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. , With global ... the challenge of how to continue to feed a growing nation. At the same ...
(Date:10/9/2017)... Phoenix, Arizona (PRWEB) , ... October 09, 2017 ... ... of Kindred, a four-tiered line of medical marijuana products targeting the needs of ... production and packaging of Kindred takes place in Phoenix, Arizona. , As operators ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... advanced instruments and applications consulting for microscopy and surface analysis, Nanoscience Instruments ... consulting, Nanoscience Analytical offers a broad range of contract analysis services for ...
(Date:10/7/2017)...  The 2017 Nobel Prize in Chemistry recognizes ... Joachim Frank and Richard Henderson ... (cryo-EM) have helped to broaden the use ... The winners worked with systems manufactured by Thermo ... resolved, three-dimensional images of protein structures that lead ...
Breaking Biology Technology:
Cached News: