HOME >> BIOLOGY >> NEWS
Multicenter study nets new lung tumor-suppressor gene

types of non-small cell lung cancer -- squamous cell carcinoma, large-cell carcinoma, and adenocarcinoma -- rather than just one or two, Wong says. "This suggests that LKB1 plays a role at major stages of the tumors' development: initiation, differentiation of normal lung cells into cancer cells, and metastasis."

An examination of human non-small-cell lung tissue suggests LKB1 mutations play a role there as well. Of 144 samples analyzed, 34 percent of the lung adenocarcinomas and 19 percent of the squamous cell carcinomas contained abnormal versions of the gene, researchers report.

"We were surprised at how significant a role LKB1 mutations play in non-small cell lung cancer development in mice," say Wong, who is also an assistant professor of medicine at Harvard Medical School. "This suggests there may be additional lung tumor-suppressor genes yet to be discovered. Were currently examining whether these results apply to human lung cancers as well and, if so, how such information can improve treatment."


'"/>

Contact: Bill Schaller
william_schaller@dfci.harvard.edu
617-632-5357
Dana-Farber Cancer Institute
5-Aug-2007


Page: 1 2

Related biology news :

1. New study warns limited carbon market puts 20 percent of tropical forest at risk
2. Clones on task serve greater good, evolutionary study shows
3. Pollution causes 40 percent of deaths worldwide, study finds
4. A study by the MUHC and McGill University opens a new door to understanding cancer
5. New study suggests Concord grape juice may provide protection against breast cancer
6. Preclinical study links gene to brain aneurysm formation
7. In limiting life span, study finds booming bacteria innocent
8. MIT study: Maturity brings richer memories
9. Chickadee, nutchatch presence in conifers increases tree growth, says CU-Boulder study
10. Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
11. New study demonstrates important role of glia in circadian timing

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/1/2020)... (PRWEB) , ... April 30, 2020 , ... ... today announced an alliance with Corritori Consulting Inc., a biopharmaceutical and regulatory services ... pharmaceutical and companion diagnostics industries. Flagship and Corritori are taking a collaborative approach ...
(Date:4/30/2020)... ... April 28, 2020 , ... ... Consultants latest effort in providing timely and critical information to life science organizations ... distancing and health safety concerns. , “Providing the most up-to-date actionable guidance and ...
(Date:4/26/2020)... NEW YORK (PRWEB) , ... April 23, 2020 , ... ... collaboration with GenScript, is developing a synthetic antibody to SARS-CoV-2, the virus that causes ... lung cells, and would be another potential treatment option for COVID-19. , The efforts ...
Breaking Biology News(10 mins):
(Date:5/14/2020)... , ... May 12, 2020 , ... ... JCS as the new distribution partner for all personal care ingredients in Russia ... portfolio and DuPont preservative portfolio for personal care. , The GENENCARE®OSMS ...
(Date:5/14/2020)... ... May 13, 2020 , ... In collaboration with ... Workflows in the Life Science Lab . The comprehensive information source was created ... purification and liquid handling to contamination control. , The content hub features the ...
(Date:5/9/2020)... LOS ANGELES (PRWEB) , ... May 08, 2020 , ... ... week’s episode of their successful business program on Sunday, May 10, 2020 and Wednesday, ... each U.S. coast! This episode’s exclusive interviews will spotlight key executives from Techolution ...
(Date:5/5/2020)... ... May 05, 2020 , ... ProductLife Group has marked ... Duburcq joins the group after 13 years at Altran, where he was Group VP ... in Immunology and being a Pharmacist, Xavier was involved in his early career in ...
Breaking Biology Technology:
Cached News: