HOME >> BIOLOGY >> NEWS
NIH awards $4.2 million grant to scientists at Scripps Research to speed DNA sequencing technologies

A team of scientists at The Scripps Research Institute in California and Oxford University in England have been awarded a $4.2 million five-year grant to conduct basic science aimed at speeding the rate at which the next generation of DNA sequencing technologies will become available to scientists and clinicians.

This award is part of a larger initiative announced today by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH). According to the NHGRI, the grants, which total $32 million, aim to advance the development of innovative sequencing technologies, reduce the cost of DNA sequencing, and expand the use of genomics in biomedical research and health care.

The new Scripps Research grant, titled "Single-Molecule DNA Sequencing with Engineered Nanopores," is a collaborative effort between the laboratories of Scripps Research Professor Reza Ghadiri, Ph.D., and Oxford Professor Hagan Bayley, Ph.D. The goal is to develop technology that enables scientists to sequence a single piece of DNA -- something that isn't yet possible.

Over the past decade, DNA sequencing costs have fallen more than 50-fold, fueled in large part by tools, technologies, and process improvements developed as part of the successful effort to sequence the human genome. However, it still costs about $10 million to sequence 3 billion base pairs the amount of DNA found in the genomes of humans and other mammals. Ultimately, NHGRI's vision is to cut the cost of whole-genome sequencing to $1,000 or less, which would enable the sequencing of individual genomes as part of routine medical care.

"Just as our fingerprints are unique, we have genetic fingerprints that are unique as well," says Ghadiri.

Ghadiri, Bayley, and their colleagues aim to engineer a device with the ability to recognize a nucleotide on the basis of changes in electrical current as it passes through a nanopore -- a naturally hollo
'"/>

Contact: Jason Bardi
jasonb@scripps.edu
858-784-9254
Scripps Research Institute
9-Aug-2005


Page: 1 2

Related biology news :

1. Argonne wins three R&D 100 awards for innovative technologies
2. ASBMB taps 8 scientists and 1 politician for top awards
3. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
4. US Department of Defense awards $1.6 million for implantable biochip research
5. 20 Kentucky firms share $1.9 million from state to match federal SBIR-STTR awards
6. The Cancer Genome Atlas awards funds for technology development
7. NIH awards nearly $21 million to fund cutting-edge research equipment
8. SNM presents awards on Capitol Hill
9. National awards for 2 University of York scientists
10. Burroughs Wellcome Fund awards $14M to support physician-scientists
11. NIH awards VBI, Mayo Clinic $2.4M to study chronic rhinosinusitis

Post Your Comments:
(Date:7/23/2014)... Ind. Spinach gave Popeye super strength, but it ... a group of scientists: the ability to convert sunlight ... physicists are part of an international group using spinach ... by which plants convert the sun,s energy into carbohydrates ... study are part of the most efficient system ever ...
(Date:7/23/2014)... , , , ... , , , , ... lifespan. The idea, they argue, would be to target the... , , ... , , , , ... , , , , , , , Medicine focuses almost entirely on ...
(Date:7/23/2014)... its grip is affecting more than the color of people,s ... a heat-loving amoeba commonly found in warm freshwater bodies, such ... made warmer than usual this year. , A 9-year-old Kansas ... after swimming in several area lakes. The amoeba enters the ... the brain. Nose plugs can lower the odds of this ...
Breaking Biology News(10 mins):Spinach could lead to alternative energy more powerful than Popeye 2Strategy proposed for preventing diseases of aging 2Strategy proposed for preventing diseases of aging 3Strategy proposed for preventing diseases of aging 4Strategy proposed for preventing diseases of aging 5Diseases of another kind 2
(Date:7/23/2014)... , July 23, 2014  Having the right people ... vital to accelerating business growth and achieving clinical and ... Association (AHA) Leadership Summit, July 20-22, 2014, in ... of hospital executives and healthcare experts discussing how partnerships ... Carrocino , President & Chief Executive Officer of Cape ...
(Date:7/23/2014)... StemGenex® , the leading resource for ... at improving the lives of patients dealing with degenerative ... disease. StemGenex believes that a commitment to the ... when providing care to patients with degenerative diseases. ... accessible to the millions of individuals currently living with ...
(Date:7/23/2014)... Iowa (PRWEB) July 23, 2014 DuPont ... the business as vice president of Agricultural Biotechnology (ABT), ... Biotechnology where he served most recently as president, chief ... biotechnology and business leadership in the seed and crop ... said Paul E. Schickler , president of DuPont ...
(Date:7/23/2014)... -- regulated information -- UCB today announced an important ... positive topline results from the latest Phase 3 ... to evaluate the efficacy and safety of ... compared to placebo, as adjunctive treatment in adult ... controlled despite treatment with one or two concomitant ...
Breaking Biology Technology:MSC and Cape Regional Medical Center Partner to Improve Cost, Quality and Outcomes 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 3DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 3Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 2Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 3Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 4Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 5Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 6Major advance in UCB pipeline: positive topline Phase 3 results for brivaracetam in epilepsy patients with partial-onset seizures 7
Cached News: