>University of Maryland Biotechnology Institute (Baltimore, Md.) $737,850. A high-speed system for confocal fluorescence imaging, subcellular photolysis, and patch clamp control of single cells will allow scientists to continue studies of calcium signaling at high temporal and spatial resolution in living cells, as well as investigations involving neuronal and brain slice imaging.

University of Texas Health Science Center (San Antonio, Texas) $1,950,000. A small-bore, 7 Tesla magnetic resonance imaging scanner will make possible non-invasive studies of a wide variety of animal sizes and species from transgenic mice to non-human primates, spanning multiple disciplines such as oncology, aging, and neurological and psychiatric disorders.

University of Washington (Seattle, Wash.) $1,040,735. A pulsed electron paramagnetic resonance/X-band electron nuclear double resonance spectrometer will be used to study the function of enzymes, structural proteins and proteins at DNA and RNA interfaces.

University of Wisconsin School of Medicine and Public Health (Madison, Wis.) $1,499,745. A cyclotron and related devices for positron emission tomography tracer development and production will enable molecular level physiological functional imaging to facilitate research involving cancer, neuroscience, cardiovascular, and regenerative medicine.

Vanderbilt University (Nashville, Tenn.) $2,000,000. A 7 Tesla human magnetic resonance imaging and spectroscopy system will facilitate research in a number of areas including: the development of advanced imaging and spectroscopic methods; studies of brain structure and function in humans as well as non-human primates; investigations of biochemistry and metabolism in vivo; and studies of cancer and the response of tumors to novel treatments.

Yale University (New Haven, Conn.) $1,054,868. New, cutting-edge DNA sequencing/genotyping tech
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Contact: Ann Puderbaugh
puderba@mail.nih.gov
301-435-0888
NIH/National Center for Research Resources
12-Jun-2007


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