HOME >> BIOLOGY >> NEWS
NIH funds innovative alzheimer's research initiated at UCSB

A completely new approach to the study of Alzheimers disease, initiated by a professor at the University of California, Santa Barbara, may solve a critical piece in the puzzle of the disease. This tragic neurological illness progressively erases memory in its millions of victims. The key to the new approach is understanding the way certain proteins in the brain fold, or rather misfold.

Michael Bowers, a professor in the Department of Chemistry and Biochemistry, developed this project, which is being funded by the National Institutes of Health. Bowerss laboratory will receive $1.3 million of the total $9 million project grant, plus biological samples worth an additional $500,000. The grant covers a five-year period. Four institutions are involved.

Bowers is using specialized chemical research methods and applying them to biology. His research will depend upon the study of rare peptides, or strings of amino acids, that are difficult to produce. These will be provided by co-investigator David Teplow, a professor at UCLAs David Geffen School of Medicine, who has been involved in Alzheimers research for over 10 years. Joan-Emma Shea, also a professor in UCSBs Department of Chemistry and Biochemistry, heads the theoretical modeling aspect of the project.

Until about five or six years ago, everyone assumed that the large amyloid plaques, or neurofibrillary tangles, that were found in the brains of Alzheimers victims were the cause of the disease, said Bowers. However, recent scientific discoveries indicate that these large, insoluble aggregates might merely be markers of the disease they do not cause the disease. Rather, smaller soluble oligomers, or peptide complexes, are now felt to be the causative agents, and I find that very interesting.

He explained that now the hunt is on for the small stuff. Because of their expertise in certain chemical methodologies, Bowers and his research group are able to track down the molecular l
'"/>

Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara
14-Feb-2007


Page: 1 2 3 4

Related biology news :

1. The Cancer Genome Atlas awards funds for technology development
2. NSF funds new Rutgers plant biomaterials initiative
3. NSF funds biofertilizer research at Rutgers-Camden
4. ResearchChannel awards matching funds for video production
5. Research grant funds studies of climate change and reef ecosystems
6. NHGRI funds large-scale sequencing centers
7. NCI funds Einstein and U. Albany NanoCollege to make worlds smallest cancer detection device
8. Worcester Polytechnic Institute receives $2 million in federal funds for biomedical research centers
9. Columbia University Medical Center receives major new NIH Clinical Science investment funds
10. NIH funds Berkeley Lab research on defense against radiological attack
11. NIH funds 14 High-End Instrumentation grants

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: NIH funds innovative alzheimer research initiated UCSB

(Date:8/27/2014)... of studies have shown that excessive iron ... Parkinson,s disease. Previous studies from Chunyan Guo ... China have shown that baicalin prevented iron ... metal transporter 1 expression, and increased ferroportin ... rotenone-induced Parkinson,s disease rats. However, the relationship ...
(Date:8/27/2014)... has shown that piglets can be weaned later with ... outcome of the study at the University,s Roseworthy campus, ... is an important finding for pig producers. It allows ... production. , "Sows don,t usually start their oestrous cycles ... piglets have been weaned," says Ms Alice Weaver, PhD ...
(Date:8/27/2014)... is a dreaded bacterium that can be found ... few weeks, 28 persons in Denmark have been infected ... supermarkets. 13 have died. , The bacterium is notoriously ... ability to adapt to changes in its surroundings, says ... with colleagues from the Department of Biochemistry and Molecular ...
Breaking Biology News(10 mins):Piglet weaning age no bar to litter frequency 2Researchers discover why Listeria bacterium is so hard to fight 2Researchers discover why Listeria bacterium is so hard to fight 3
(Date:8/26/2014)... An analysis by Replikins, Ltd. of Pubmed data of ... Pubmed, has revealed extensive conservation and sharing of specific ... of specific Replikin gene structures has permitted the formulation ... for the H5N1 influenza vaccine and the Taura Syndrome ... be effective (1,2). This Dengue vaccine ...
(Date:8/26/2014)... 2014   Lycera Corp ., a biopharmaceutical ... to treat autoimmune disease and cancer based on ... appointment of Harinder Singh , Ph.D., as ... Singh will lead the board,s efforts to provide ... research programs and pipeline of therapies targeting unmet ...
(Date:8/26/2014)... San Francisco, CA (PRWEB) August 26, 2014 ... to reach USD 8,020.1 million by 2020, according to ... demand for personalized medicine and theranostics, and the subsequent ... be key factors driving market growth over the next ... population and chronic diseases such as cancer, coupled with ...
(Date:8/26/2014)... 26, 2014 Genedata, a leading ... and life science research, today announced the ... be held in Asia, Europe, and North America ... companies and leading research organizations will gather for ... case studies, and upcoming challenges in all areas ...
Breaking Biology Technology:Lycera Appoints Harinder Singh, Ph.D., as Chair of Scientific Advisory Board 2Lycera Appoints Harinder Singh, Ph.D., as Chair of Scientific Advisory Board 3World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 2World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 3World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 4World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 5World Molecular Diagnostics Market Is Expected To Grow To $8,020.1 Million From 2014 To 2020: Grand View Research, Inc 6Thought Leaders to Explore Innovations in SPR & Combination Screening at Genedata Screener User Group Meetings 2Thought Leaders to Explore Innovations in SPR & Combination Screening at Genedata Screener User Group Meetings 3
Cached News: