HOME >> BIOLOGY >> NEWS
NIH funds innovative alzheimer's research initiated at UCSB

A completely new approach to the study of Alzheimers disease, initiated by a professor at the University of California, Santa Barbara, may solve a critical piece in the puzzle of the disease. This tragic neurological illness progressively erases memory in its millions of victims. The key to the new approach is understanding the way certain proteins in the brain fold, or rather misfold.

Michael Bowers, a professor in the Department of Chemistry and Biochemistry, developed this project, which is being funded by the National Institutes of Health. Bowerss laboratory will receive $1.3 million of the total $9 million project grant, plus biological samples worth an additional $500,000. The grant covers a five-year period. Four institutions are involved.

Bowers is using specialized chemical research methods and applying them to biology. His research will depend upon the study of rare peptides, or strings of amino acids, that are difficult to produce. These will be provided by co-investigator David Teplow, a professor at UCLAs David Geffen School of Medicine, who has been involved in Alzheimers research for over 10 years. Joan-Emma Shea, also a professor in UCSBs Department of Chemistry and Biochemistry, heads the theoretical modeling aspect of the project.

Until about five or six years ago, everyone assumed that the large amyloid plaques, or neurofibrillary tangles, that were found in the brains of Alzheimers victims were the cause of the disease, said Bowers. However, recent scientific discoveries indicate that these large, insoluble aggregates might merely be markers of the disease they do not cause the disease. Rather, smaller soluble oligomers, or peptide complexes, are now felt to be the causative agents, and I find that very interesting.

He explained that now the hunt is on for the small stuff. Because of their expertise in certain chemical methodologies, Bowers and his research group are able to track down the molecular l
'"/>

Contact: Gail Gallessich
gail.g@ia.ucsb.edu
805-893-7220
University of California - Santa Barbara
14-Feb-2007


Page: 1 2 3 4

Related biology news :

1. The Cancer Genome Atlas awards funds for technology development
2. NSF funds new Rutgers plant biomaterials initiative
3. NSF funds biofertilizer research at Rutgers-Camden
4. ResearchChannel awards matching funds for video production
5. Research grant funds studies of climate change and reef ecosystems
6. NHGRI funds large-scale sequencing centers
7. NCI funds Einstein and U. Albany NanoCollege to make worlds smallest cancer detection device
8. Worcester Polytechnic Institute receives $2 million in federal funds for biomedical research centers
9. Columbia University Medical Center receives major new NIH Clinical Science investment funds
10. NIH funds Berkeley Lab research on defense against radiological attack
11. NIH funds 14 High-End Instrumentation grants

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/9/2016)... 2016 Aware, Inc. (NASDAQ: AWRE ), a leading ... its fourth quarter and year ended December 31, 2015.  ... quarter of 2015 was $6.9 million, an increase of 61% compared ... in the fourth quarter of 2015 was $2.6 million compared to ... --> --> Higher revenue and operating income ...
(Date:2/8/2016)... 2016 Worldcore is ... innovation for clients, comfort and unbeatable security, with ... --> Worldcore is the first EU-regulated ... comfort and unbeatable security, with a Voice Biometrics ... Worldcore is the first EU-regulated global payment ...
(Date:2/4/2016)... LONDON , Feb. 4, 2016 ... is apparently one of the most popular hubs ... Project, MetaHIT and other huge studies of human ... that past few years, the microbiome space has ... applied biomedical research. This report focuses on ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... and GERMANTOWN, Maryland , February ... Prime Standard: QIA) today announced the introduction of more ... expression profiling, expanding QIAGEN,s portfolio of Sample to Insight ... to select from over 20,000 human genes and lncRNA ... genes, cellular phenotypes and disease processes. --> ...
(Date:2/11/2016)... , Feb. 11, 2016  Dovetail Genomics™ LLC today ... beta program for a planned metagenomic genome assembly service. ... company,s metagenomic genome assembly method in a talk on ... Biology & Technology conference in Orlando, Fla. ... highly complex datasets is difficult. Using its proprietary ...
(Date:2/11/2016)... (PRWEB) , ... February 11, 2016 , ... ... of its new stem cell treatment clinic in Quito, Ecuador. The new facility ... and trauma applications to patients from around the world. , The new ...
(Date:2/10/2016)... Feb.10, 2016 ASAE is introducing a hybrid ... Companies (AMC) the option of joining or renewing through ... determined by staff size, every employee in any size ... and reap all available member benefits.   ... organizational membership options will allow organizations of any size ...
Breaking Biology Technology:
Cached News: