HOME >> BIOLOGY >> NEWS
NYU algorithm enhances ability to detect cancer genes

Researchers at New York University's Courant Institute of Mathematical Sciences have developed a new algorithm that enhances the ability to detect a cancer gene, and have applied their algorithm to map the set of tumor-suppressor genes involved in lung cancer. The algorithm uses data from Affymetrix's gene-chips that can scan hundreds of patients' genomes to find gains and losses in gene-copies. The findings will appear in the July issue of the American Journal of Human Genetics.

The study was conducted by Iuliana Ionita, a PhD student in computer science, Raoul-Sam Daruwala, a former research scientist from Courant Bioinformatics group and currently at Google, and Courant Professor Bud Mishra. Mishra is a professor of computer science and mathematics at the Courant Institute and also has an appointment in the Department of Cell Biology at NYU's School of Medicine.

Previous research has found that certain gene-chips--a technology that allows the genome-wide screening for mutations in genes or changes in gene expressions all at once--shed light on genes and mechanisms involved in the onset and spread of cancer. Specifically, chromosomal segments, when deleted in a single or both copies of genomes of a group of cancer patients, point to locations of tumor suppressor genes implicated in the cancer. The NYU study focused on automatic methods for reliable detection of such genes, their locations, and their boundaries. For this purpose, the NYU scientists sought to devise an efficient and novel statistical algorithm to map tumor suppressor genes using a multi-point statistical score function. Their algorithm is unique in that it exploits the high resolution of gene-chips and prior biological models through Bayesian statistics in order to optimally pinpoint the genes involved in the cancer, even when these genomes may have many other unrelated deletions, which happen as "collateral damage" to the genomes as the cancer progresses to an advanced stage. <
'"/>

Contact: James Devitt
james.devitt@nyu.edu
212-998-6808
New York University
9-May-2006


Page: 1 2 3

Related biology news :

1. New algorithms classify outcomes of nonsmall cell lung cancer patients
2. NYU team develops enhanced algorithm for detecting changes in cancer genomes
3. Cancer drug enhances long-term memory
4. Proteasome activator enhances survival of Huntingtons disease neuronal model cells
5. Dartmouth researchers identify a gene that enhances muscle performance
6. Getting ahead of cancer: SPECT/Spiral CT technology enhances bone scanning, earlier diagnosis
7. Delft mathematician enhances protectiveness of military uniform
8. Elevated temperature enhances success of viral cancer therapy
9. Pulsating ultrasound enhances gene therapy for tumors
10. Moderate alcohol consumption enhances the formation of new nerve cells
11. Reading ability protects brain from lead exposure

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: NYU algorithm enhances ability detect cancer genes

(Date:3/23/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... commerce market, announces its biometric payment technology, the Wocket® smart ... starting March 30 th . The ... New York markets. Gino ... our new ad campaign following the recent initial shipment of ...
(Date:3/20/2015)... 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... focused on the growing mobile commerce market, announces its ... of the products featured in 2015 "I Want That" ... PM EST on the DIY Network.   ... Vegas , site of the 2015 International CES ...
(Date:3/18/2015)... Florida , March 18, 2015 ... as businesses, new revolutionary smart wallets and apps continue to ... Companies currently entrenched in the mobile payment industry in focus ... Group Holding Ltd. (NYSE: BABA ), Apple Inc. ... GOOG ) and Facebook Inc. (NASDAQ: FB ) ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 2NXT-ID's Wocket Smart Wallet to Launch New CNBC Regional TV Ad Campaign 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6
(Date:4/23/2015)... DIEGO , April 23, 2015  Neurocrine Biosciences, ... Company will report its first quarter 2015 results before ... Neurocrine will then host a live conference call and webcast ... update Thursday morning, April 30, 2015 at 8:00 a.m. ... can access the live conference call by dialing 866-952-1906 ...
(Date:4/23/2015)... Calif. , April 23, 2015  Veracyte, Inc. (NASDAQ: ... into a definitive agreement to sell approximately $40 million ... the agreement, the investors will purchase an aggregate of ... of $8.15 per share, the closing stock price on ... new and existing investors, including Broadfin Capital, Camber Capital, ...
(Date:4/23/2015)... 23, 2015  Metanome, Inc., an industry leader ... has changed its name to Diversigen, Inc.  The ... the single commercial source for the myriad of ... the diverse opportunities of the microbiome.  From the ... – including those that are difficult to handle, ...
(Date:4/23/2015)... CA (PRWEB) April 23, 2015 Delpor, ... today announced that the United States Patent and Trademark ... Company’s NANOPOR™ technology. US Pat. No. ... Delpor’s microfabricated drug delivery device for the ... proprietary NANOPOR™ technology for the sustained (zero-order) release of ...
Breaking Biology Technology:Neurocrine Biosciences Announces Conference Call and Webcast to Report First Quarter 2015 Results 2Veracyte, Inc. Announces $40 Million Private Placement 2Veracyte, Inc. Announces $40 Million Private Placement 3Veracyte, Inc. Announces $40 Million Private Placement 4Metanome Announces Corporate Name Change to Diversigen 2Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 2Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 3
Cached News: