HOME >> BIOLOGY >> NEWS
Nanoparticles create biocompatible capsules

An innovative strategy of mixing lipids and nanoparticles to produce new drug and agricultural materials and delivery vehicles has been developed by researchers at the University of Illinois at Urbana-Champaign.

"This is a new way to make nano-size capsules of a biologically friendly material," said Steve Granick, a professor of materials science and engineering, chemistry and physics. "The hollow, deformable and biofunctional capsules could be used in drug delivery, colloidal-based biosensors and enzyme-catalyzed reactions."

Lipids are the building blocks of cell membranes. The construction of useful artificial lipid vesicles was previously not possible, because the vesicles were too delicate. Granick and graduate student Liangfang Zhang found a way to stabilize lipids and stop their destruction. The researchers describe their technique in a paper accepted for publication in the journal Nano Letters, and posted on its Web site.

To stabilize lipids, the researchers begin by preparing a dilute solution of lipid capsules of a particular size. After encapsulating chemicals in the capsules or adsorbing molecules on their surfaces, they add charged nanoparticles to the solution. The nanoparticles adhere to the capsules and prevent further growth, freezing them at the desired size. The lipid concentration can then be increased without limits.

"We form an 'army' of uniform capsules, and then we can use them in a military fashion," said Granick, who also is a researcher at the Frederick Seitz Materials Research Laboratory and at the Beckman Institute for Advanced Science and Technology. "That is, the capsules are well behaved, and follow orders without wandering off and propagating."

As proof of concept, Granick and Zhang encapsulated fluorescent dyes within lipid capsules. No leakage occurred, and the lipids proved stable against further fusion.

"This opens the door to using biologically friendly capsule delivery vehicles in
'"/>

Contact: James E. Kloeppel, Physical Sciences Editor
kloeppel@uiuc.edu
217-244-1073
University of Illinois at Urbana-Champaign
6-Mar-2006


Page: 1 2

Related biology news :

1. Nanoparticles hitchhike on red blood cells: a potential new method for drug delivery
2. Nanoparticles carry chemotherapy drug deeper into solid tumors
3. Cancer tip -- Nanoparticles can damage DNA, increase cancer risk
4. Little lifesavers -- Nanoparticles improve delivery of medicines and diagnostics
5. Nanoparticles for delivery of prostate cancer treatment
6. MIT, Brigham: Nanoparticles armed to combat cancer
7. Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
8. Newly created cancer stem cells could aid breast cancer research
9. MIT creates 3-D images of living cell
10. Not all embryonic stem cell lines are created equal
11. Researchers use adult stem cells to create soft tissue

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/1/2019)... (PRWEB) , ... July 30, 2019 , ... ... Behrens as the George B. and Joy Rathmann Professor in Bioprocessing and Director ... an innovative leader in the life sciences industry and possesses more than 25 ...
(Date:7/26/2019)... ANGELES (PRWEB) , ... July 26, 2019 , ... ... to announce an exclusive interview with Helius Medical Technologies CEO Phil Deschamps to ... trauma. , Helius Medical Technologies is a neurotech company in the ...
(Date:7/23/2019)... ... 22, 2019 , ... Personalized Stem Cells, Inc (“PSC”), a human adipose-derived stem ... of a person’s own adipose-derived stem cells to treat their osteoarthritis. The first clinical ... in the knee. , This is the first of several planned clinical ...
Breaking Biology News(10 mins):
(Date:8/4/2019)... ... August 02, 2019 , ... Cirtec Medical Corporation, a strategic outsourcing partner for ... has begun construction on a 30,000 sq. ft. manufacturing facility in the Coyol ... , The facility, which is expected to be fully operational by the end of ...
(Date:7/23/2019)... ... July 22, 2019 , ... ... best-in-class services in the fields of 3D tissue imaging , digital ... Visikol initially started back in 2013 as a products company. These products are ...
(Date:7/17/2019)... ... July 15, 2019 , ... CRISPR is often thought ... certain trait can be removed, replaced, or edited, but Yiping Qi, assistant professor in ... these traditional applications in his latest publication in Nature Plants. In this comprehensive review, ...
(Date:7/11/2019)... (PRWEB) , ... July 11, 2019 , ... At the ... provided complimentary regenerative therapies to eight military Veterans under the R3 Heroes Program. The ... complimentary. , The R3 Heroes Program allow anyone to nominate a military Veteran, teacher ...
Breaking Biology Technology:
Cached News: