Nanotechnology propels advances in regenerative medicin...( ion in these animals according to Samu...)

ion in these animals, according to Samuel Stupp, Ph.D., chemist and director of the Institute of Bionanotechnology in Medicine at Northwestern University in Evanston, Ill. The finding is an important research advance that one day could help rapidly restore cardiovascular function in people who have heart disease, Stupp says. The self-assembling nanoparticles - made from naturally occurring polysaccharides and molecules known as peptide amphiphiles - boost chemical signals to nearby cells that induce formation of new blood vessels and this may be the mechanism through which they restore cardiovascular function. One month later, the hearts of the treated mice were capable of contracting and pumping blood almost as well as healthy mice. In contrast, the hearts of untreated mice contracted about 50 percent less than normal. In other recent studies using a similar technique, Stupp and his colleagues found nanoparticles hastened wound healing in rabbits and, after islet transplantation, cured diabetes in mice. Nanoparticles with other chemical compositions accelerate bone repair in rats and promote the growth of neurons in mice and rats with spinal cord injuries, he says. (COLL 218, Monday, Sept. 11, 3:50 p.m.)

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11-Sep-2006

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