HOME >> BIOLOGY >> NEWS
Natural polyester makes new sutures stronger, safer

CAMBRIDGE, Mass. -- With the help of a new type of suture based on MIT research, patients who get stitches may never need to have them removed.

A biopolymer suture cleared last month by the FDA is made of materials that the human body produces naturally, so they can be safely absorbed once the wound is healed. They are also 30 percent stronger than sutures now used and very flexible, making them easier for surgeons to work with.

The sutures were developed by Tepha, Inc., a Cambridge company that hopes to use the same material to produce an array of absorbable medical devices, including stents, surgical meshes and possibly a heart valve scaffold, says Simon Williams, CEO of Tepha and a former MIT postdoctoral associate.

Williams said he envisions that the new sutures will be used for abdominal closures, which are prone to re-opening, and to stitch tendons and ligaments.

Developed using a method created at MIT, the absorbable sutures are the first made from material produced by genetically modified bacteria.

About 20 years ago, researchers in the laboratory of MIT biology professor Anthony Sinskey started swapping genes between different bacteria, hoping to achieve industrial production of desirable natural compounds synthesized by those bacteria.

The researchers focused their "biopolymer engineering" efforts on a group of genes that code for enzymes in a pathway that produces polyesters. Those polyesters can be broken down into metabolites naturally produced by humans, so they cause no harm when absorbed.

Once the genes were identified, they could be transferred into a strain of industrial E. coli that can produce large quantities of the strong, flexible polymer.

The FDA cleared the biopolymer sutures on Feb. 8, and Williams said Tepha plans to start marketing them soon, in partnership with another company.

"Not only is it technically and in an engineering sense a tremendous
'"/>

Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology
22-Mar-2007


Page: 1 2

Related biology news :

1. Elsevier partners with National Natural Science Foundation of China
2. Natural compound and exercise boost memory in mice
3. Natural immune-control system may aid treatment of autoimmune disease and tissue rejection
4. Natural anti-freeze -- how arthropods survive the cold
5. Natural mechanism for immune suppression paves way for cancer trials
6. Natural antibiotics yield secrets to atom-level imaging technique
7. Natural fiber may take extra pounds away
8. Natural gut hormone offers hope for new obesity drug
9. Naturally occurring enzyme can break down key part of Alzheimers plaques
10. Natural anti-viral enzyme helps keep cancer cells alive, researchers find
11. Natural resources and the economy: hand in hand

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/28/2020)... ... ... In an upcoming episode scheduled for the fall of 2020, Advancements with ... Check local listings for more info. , Today, the majority of testing is performed ... throughout the country. Results are then available several days later. Now, in an effort ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... antibody development services, today announced that the company has received ISO9001:2015 certification ... pharmaceutical, diagnostics, and research industries. The decision to pursue ISO9001 accreditation demonstrates ...
(Date:6/23/2020)... ... June 22, 2020 , ... The field of quantitation ... binding assays (LBA) have dominated this area. However, the use of mass spectrometry in ... This now necessitates the question “How do you choose which approach to use (LBA ...
Breaking Biology News(10 mins):
(Date:8/3/2020)... ... , ... Introducing Ardent Animal Health – MediVet Biologics rebrands company and positions ... as MediVet Biologics since its formation in 2016, the company is relaunching itself under ... build on its base of innovative therapies for osteoarthritis and cancer. , ...
(Date:7/31/2020)... Mass. and SOMERSET, N.J (PRWEB) , ... July ... ... leading genome editing company, and Catalent, the leading global provider of advanced delivery ... consumer health products, today announced that they have entered into a strategic partnership ...
(Date:7/18/2020)... ... ... After research model surgery and catheter implantation, the long journey of catheter ... of a successful study, while protecting and accessing the catheter or device post-surgery is ... from Envigo in a live webinar on Wednesday, August 5, ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... of Technology (MIT) has expanded the company’s exclusive license to include clinical ... the point-of-care diagnostic market, focusing initially on the SARS-CoV-2 biosensor. CANARY’s™ ...
Breaking Biology Technology:
Cached News: