HOME >> BIOLOGY >> NEWS
Nature's weapon against nerve agents

An enzyme found naturally in the blood could help protect soldiers against the effects of the deadly nerve agent sarin, reports Cath ODriscoll in the Society of Chemical Industrys magazine Chemistry & Industry, the magazine of the SCI. The US military is funding a three-year study to evaluate the effectiveness of the enzyme, known as GOT, in protecting animals against the damaging cognitive and coordination problems resulting from exposure to the organophosphorus nerve agent.

The study will be carried out by Israeli firm Braintact, and follows earlier unpublished work with rats which showed the enzyme successfully protected the animals against neurological problems caused by exposure to paraoxon, a model compound for nerve agents such as sarin, soman and VX.

GOTs ability to protect against neurological damage, the company claims, is down to the fact it can bind to, and chemically inactivate, a chemical called glutamate, also found in the blood and brain. In normal, healthy individuals, glutamates role is as a neurotransmitter carrying nerve impulses between cells. When cells are damaged or dying, however, as on exposure to nerve agents or as a result of other forms of brain injury including stroke or disease they release far more glutamate than normal, over-exciting and killing nearby nerve cells.

In related work published earlier this year, by Vivian Teichberg at the Weizmann Institute of Science and researchers at the Beer Sheva University in Israel, activation of GOT in the blood was found to prevent much of the brain damage caused after brain injury in rats. It appears that most of the damage that is caused is due to excess glutamate since we can entirely prevent the brain cell death after traumatic injury, Teichberg said.


'"/>

Contact: SCI Press Office
press@soci.org
44-020-759-81588
Society of Chemical Industry
29-Jul-2007


Page: 1

Related biology news :

1. Natures secrets yield new adhesive material
2. Natures process for nitrogen fixation caught in action
3. Natures strongest glue could be used as a medical adhesive
4. Secondary waste from chemical weapons stockpile disposal
5. Aphids make chemical weapons to fight off killer ladybirds
6. Alien plants attack using resource conservation as weapon, researchers say
7. Replacement warhead program poses challenges for weapons complex
8. UBC researchers find new superbug weapon for near-empty antibiotics arsenal
9. New sensor detects gaseous chemical weapon surrogates in 45 seconds
10. Scripps research scientists: Compounds show significant promise against potential bioweapon toxins
11. Cellular pathway yields potential new weapon in vaccine arsenal

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/13/2020)... ... 11, 2020 , ... Bode Technology (Bode), a ... genealogy team. Bode’s Forensic Genealogy Service (FGS) continues to deliver investigative ... methods. The team has added experienced genealogists, each having over a decade of ...
(Date:6/5/2020)... ... June 04, 2020 , ... Murrieta Genomics has announced that ... for simplified sample preparation for Next Generation Genomic Sequencing (NGS) . This is ... and complexity of sample preparation. , “I have been at the bench for over ...
(Date:6/2/2020)... ... June 02, 2020 , ... ... labeling software developer and solutions provider, today reported that the implementation of ... and compliance by 100%, resulting in greater efficiency for global biotechnology company, ...
Breaking Biology News(10 mins):
(Date:5/21/2020)... ... May 21, 2020 , ... ... trials will cause long-term harm , Contrary to conventional wisdom that says the ... finds many companies will emerge from the pandemic commercially weaker, dealing with ...
(Date:5/21/2020)... BALTIMORE (PRWEB) , ... May 19, 2020 , ... Eaton ... with the addition of Popper and Company, a biotechnology and medical technology-focused strategy and ... continues to grow in the United States, linking US and Asia Pacific healthcare innovators ...
(Date:5/15/2020)... ... May 14, 2020 , ... ... working cell banks and hMSC bioprocess systems, today announced the launch of ... hMSC-derived extracellular vesicles (EVs). RoosterCollect™-EV-CC is the only system designed with hMSC-EV ...
(Date:5/15/2020)... , ... May 14, 2020 , ... This new service ... and the most pressing questions answered quickly as the need arises. Lachman’s OnCall SMEs ... valuable advice at affordable rates. , Lachman OnCall™ SMEs are available normal business ...
Breaking Biology Technology:
Cached News: