HOME >> BIOLOGY >> NEWS
New $1.16 million study investigates how dietary iron is used by cells

BUFFALO, N.Y. -- A four-year study on iron metabolism within cells, an essential process that impacts both iron deficiency and iron toxicity, conditions responsible for a multitude of human diseases, is underway at the University at Buffalo funded by a $1.16 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Daniel Kosman, Ph.D., professor of biochemistry in the UB School of Medicine and Biomedical Sciences, is lead researcher on the study.

The concern about how iron is managed in our cells has never been more acute, said Kosman. The reasons for this are three-fold. First is the endemic problem of iron deficiency that the World Health Organization estimates afflicts 80 percent of the worlds population, or more than 5 billion people.

Iron deficiency is not confined to developing nations. In the U.S., 5 percent of newborns and 7 percent of new mothers have clinical symptoms of iron deficiency. Reducing the incidence of this nutritional deficit is one of the objectives of the U.S. Department of Health and Human Services Healthy People 2010 program.

Second is the broad recognition that the corrosive chemistry associated with iron and oxygen interactions is a major factor in a multitude of human diseases.

Too much iron in tissues, called iron-loading, is thought to increase the risk of tumor development, infection, cardiomyopathy, joint disorders and several endocrine and neurodegenerative disorders.

And third, we now have an increasingly sophisticated knowledge and understanding of iron metabolic pathways, the proteins involved in these pathways and how these pathways are regulated in all organisms, making this issue ripe for investigation, he said.

Kosman proposes that a general mechanism of cellular iron metabolism requires that iron-handling proteins involved in sequential steps in the pathway must be architecturally arranged contiguo
'"/>

Contact: Lois Baker
ljbaker@buffalo.edu
716-645-5000 x1417
University at Buffalo
21-Jun-2007


Page: 1 2

Related biology news :

1. US Department of Defense awards $1.6 million for implantable biochip research
2. Nottingham biosciences million pound injection
3. $9 million EPSCoR grant to foster integrated research
4. 20 Kentucky firms share $1.9 million from state to match federal SBIR-STTR awards
5. $125 million bioenergy initiative powered by Midwest ag industry, MSU research
6. UC Davis is partner in new $125 million federal bioenergy research center
7. Energy department selects 3 Bioenergy Research Centers for $375 million in federal funding
8. The BBVA Foundation commits 2.4 million euros to research in Ecology and Conservation Biology
9. 5.9 million award gives UK aging research a new lease on life
10. NIH awards nearly $21 million to fund cutting-edge research equipment
11. University of Liverpool launches 10 million small animal teaching hospital

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/23/2018)... ... ... have hosted a variety of groups this year – both new guests and those returning ... and more, have all visited the La Jolla-based venue time and time again as a ... is due to Lajollacooks4u’s signature team-building format, a way for teams to not only interact ...
(Date:8/21/2018)... MADISON, Wis. (PRWEB) , ... August 21, 2018 ... ... of high throughput screening (HTS) solutions, Bellbrook Labs is dedicated to offering customers ... regarding biochemical assays, visitors will find a seamless transition between products, with relevant ...
(Date:8/17/2018)... CASTLE ROCK, Colo. (PRWEB) , ... August 16, 2018 , ... ... for facioscapulohumeral muscular dystrophy (FSHD), announced that its Colorado Chapter will be holding its ... event, scheduled for September 8th at the Philip S. Miller Park, advocates for public ...
Breaking Biology News(10 mins):
(Date:9/12/2018)... Wash. (PRWEB) , ... September 11, 2018 , ... ... is proud to add flat sheet Forward Osmosis (FO) membranes from Fluid Technology ... FO membranes manufactured by FTS H2O are constructed from cellulose triacetate (CTA) material. ...
(Date:9/7/2018)... ... September 06, 2018 , ... ... September 25th-28th is a meeting of “The industry’s preeminent event on novel drug ... discovery scientists powerful tools to study these emerging targets in a quest to ...
(Date:9/7/2018)... ANN ARBOR, Mich. (PRWEB) , ... September 06, 2018 , ... ... of Directors. Dunbar has spent his career as an executive and leader of numerous ... Biologics, a private cell therapy and biologics company acquired by Thompson Street Capital in ...
(Date:8/31/2018)... ... August 30, 2018 , ... Small, wireless and networked describes more than the ... connected, too. Draper’s latest system is tiny in size, but is poised to make ... in the new implant design is the growing awareness that disease often involves complex ...
Breaking Biology Technology:
Cached News: