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New bipolar survey: Patients' satisfaction influenced

toms, as a single agent.8

The announcement of these landmark survey results coincides with other important data presented at the WCBP, which address the clinical benefits that SEROQUEL offers bipolar disorder consumers. The preliminary data show that patients with bipolar depression taking SEROQUEL:

  • Showed a statistically significant decrease in levels of depression, as measured by the MADRS* score from week one through to the end of the study2. This study included rapid-cycling patients who often experience symptoms that are more severe and harder to treat than non rapid-cycling patients2

  • Showed significantly greater improvement in anxiety symptoms versus placebo, as measured using the HAM-A** rating scale 3

  • Showed significantly greater improvement in quality of life over placebo by week four (at doses of both 300mg and 600mg), as measured by the Q-LES-Q SF*** questionnaire 4

"The preliminary results from the Thinking Ahead Survey are extremely important and reflect the need for efficacious and well-tolerated treatments to help people living with bipolar disorder to experience real quality of life benefits in terms of symptom control, minimised side effects, and enhanced functioning," comments Dr Eduard Vieta from the University of Barcelona and Thinking Ahead taskforce member. "The data presented this week on SEROQUEL offers real hope for bipolar patients. We know that SEROQUEL can provide broad-based efficacy and trusted tolerability in bipolar disorder and schizophrenia, which allows us to be confident that patients will comply with their treatment in the long-term, thereby significantly improving the likelihood of a successful treatment outcome."

SEROQUEL is licensed in 70 countries for the treatment of mania associated with bipolar disorder, including the US, Canada and several European countries. SEROQUEL has also been licensed for the treat
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Contact: Lisa O'Sullivan
lisa.o'sullivan@shirehealthinternational.com
44-207-108-6515
Shire Health International
29-Jun-2005


Page: 1 2 3

Related biology news :

1. New databases put wings on search for bipolar risk genes
2. $9M grant awarded to University of Cincinnati for bipolar disorder research
3. Genetic roots of bipolar disorder revealed by first genome-wide study of illness
4. Delayed treatment of childhood-onset bipolar disorder results in negative outcome in adults
5. Gene controlling circadian rhythms may be involved in onset of bipolar disorder
6. Extreme irritability -- is it childhood bipolar disorder?
7. Fear circuit flares as bipolar youth misread faces
8. Clock molecules sensitivity to lithium sheds light on bipolar disorder
9. Link suggested between regions on two chromosomes and bipolar disorder
10. Research zeros in on bipolar disorder genes, link with thyroid condition
11. Beyond lithium for bipolar disorder

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