HOME >> BIOLOGY >> NEWS
New breast cancer study shows hormonal therapy not enough

SAN ANTONIO -- Many postmenopausal women with hormone-dependent breast cancer (requires estrogen and/or progesterone to grow) may be undertreated if they do not receive chemotherapy in addition to hormonal therapy after surgery, according to a Loyola University Health System, Maywood, Ill., study.

Loyola's Dr. Kathy S. Albain presented the results of a 10-year follow-up of The Breast Cancer Intergroup of North America Trial 0100 at the late breaking session of the San Antonio Breast Cancer Symposium annual meeting here today.

"The research shows that, in many cases, tamoxifen or other hormonal therapy alone is not optimal," said principal investigator and first author Albain, professor, division of hematology/oncology, Department of Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Ill.

"Overall, chemotherapy helped stop the cancer from recurring in postmenopausal women with receptor-positive breast cancer that has spread to the lymph nodes," said Albain. "This survival advantage was greatest when tamoxifen followed chemotherapy, rather than given concurrently.

"Ten-year disease-free-survival estimates were 48 percent for those treated with tamoxifen alone; 53 percent for concurrent chemohormonal therapy; and 60 percent for sequential therapy," said Albain, director, Breast Research Program; co-director of the multidisciplinary Breast Oncology Center; and director of the Thoracic Oncology Program, Cardinal Bernardin Cancer Center, Loyola University Health System, Maywood, Ill.

Albain and colleagues conducted a 10-year follow-up of 1,477 patients. A total of 550 patients received concurrent chemohormonal therapy (CAFT) (cyclophosphamide, doxorubicin, 5-fluorouracil, tamoxifen); another 566 patients received sequential chemohormonal therapy (CAF-T); and 361 patients received tamoxifen alone.

"Long-term follow-up of this large North A
'"/>

Contact: Joanne Swanson
jswanson@lumc.edu
708-216-2445
Loyola University Health System
8-Dec-2004


Page: 1 2

Related biology news :

1. Newly created cancer stem cells could aid breast cancer research
2. New study suggests Concord grape juice may provide protection against breast cancer
3. U-M researchers identify gene involved in breast cancer
4. Additional mammogram readers improve breast cancer detection
5. Study finds Western-style meat-sweet diet increases risk of breast cancer in postmenopausal women
6. Link between immune system and mammary gland could shed new light on breast cancer
7. Sentinel lymph node biopsy is associated with breast cancer rates
8. Pregnancy nausea/vomiting may indicate lower risk of breast cancer
9. Scripps research scientists show protein accelerates breast cancer progression in animal models
10. Screening approach leads to discovery of gene linked to breast cancer
11. Scientists develop new drugs to fight colon and breast cancer more effectively

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/8/2019)... ROSKILDE, Denmark and RALEIGH, N.C. (PRWEB) , ... ... ... leader in micro acoustic and micro mechanical technologies and solutions for hearing instruments ... sensor technology, today announced BiometRIC, the first ever hearing aid receiver in canal ...
(Date:1/4/2019)... ... January 02, 2019 , ... Lifecycle Biotechnologies announces ... life science tools and service supplier turned 40 in 2018 and for the ... features not just part numbers like most catalogs, but rather, insightful information into ...
(Date:12/27/2018)... FRANCISCO (PRWEB) , ... December 27, 2018 , ... ... annual Microbiome Conference at JPM as part of the JP Morgan 37th Annual ... innovative scientists and physicians, and members of the investment community. , Since ...
Breaking Biology News(10 mins):
(Date:12/10/2018)... ... December 10, 2018 , ... ... Contract Development and Manufacturing Organization (CDMO) with sites in China and the ... manufacturing, and aseptic fill finish solutions for monoclonal antibody (mAb) and antibody-drug ...
(Date:12/5/2018)... ... ... The incredible life story of former refugee and LG Sonic CEO Yousef ... the European Commissioner for Research and Innovation. , In his November 27th speech ... spoke at length of Yousef’s life and journey, citing the man who convinced him ...
(Date:12/5/2018)... Va. and LONDON (PRWEB) , ... ... ... Research Group (ARG), an established North American full-service contract research organization (CRO), ... Effective immediately, the transaction significantly strengthens ARG’s reach and experience in the ...
(Date:11/28/2018)... ... November 28, 2018 , ... Earlier this month, Lajollacooks4u's ... as well as experience the height of truffle season. , Her first ... pristine countryside. Staying in the exclusive Black Truffle Lodge in the small mountain village ...
Breaking Biology Technology:
Cached News: