HOME >> BIOLOGY >> NEWS
New chemistry method uses 'test tubes' far smaller than the width of a hair

Using a water droplet 1 trillion times smaller than a liter of club soda as a sort of nanoscale test tube, a University of Washington scientist is conducting chemical analysis and experimentation at unprecedented tiny scales.

The method captures a single cell, or even a small subcellular structure called an organelle, within a droplet. It then employs a powerful laser microscope to study the contents and examine chemical processes, and a laser beam is used to manipulate the cell or even just a few molecules, combining them with other molecules to form new substances.

This nanoscale "laboratory" is so minuscule that it covers just 1 percent of the width of a human hair, said Daniel Chiu, a UW associate chemistry professor who is developing the unique method.

"Anything you can do in the test tube we hope to be able to do in the droplet. We just don't need a lot of cells. We don't even need one cell, just a few molecules," Chiu said.

The new approach makes it easier to get a wide range of information about a cell. Researchers typically use microscopy to see how proteins move within a cell and collect spatial information, but that provides very little biochemical information, Chiu said. Likewise, they can use large amounts of material in a test tube to understand biochemical processes, but that doesn't provide the fine detail of microscopy.

"The cell is very small but it is very complex," Chiu said. "It has many hundreds of thousands of proteins. It is probably the ultimate nanomachine."

The new method, employing a process called microfluidics, allows researchers to perform chemical analysis and to study structure and form at the same time.

The tiny droplet is contained in a microfluidic device, which is far too small to be seen with the naked eye and is mounted on a platform about the size of a dime so researchers can carry it from one place to another. The device has water in one channel and oil in an adjo
'"/>

Contact: Vince Stricherz
vinces@u.washington.edu
206-543-2580
University of Washington
29-Aug-2005


Page: 1 2

Related biology news :

1. SNM initiatives supported by inclusions in NAS Report on competitiveness of US chemistry research
2. Scientists propose the kind of chemistry that led to life
3. Turning the tables in chemistry
4. 2007 Image of the Year: Molecular imaging relates human brain chemistry to aggressive behavior
5. Better chemistry through living models
6. New chemistry approach promises less expensive drugs
7. Psychologist explains the neurochemistry behind romance
8. UCSD scientists establish connection between life today and ancient changes in ocean chemistry
9. IUBMB selects Wiley to publish Biochemistry and Molecular Biology Education
10. Using chemistry to predict the dynamics of clotting in human blood
11. Comments, experts and background on the 2006 Nobel Prize in chemistry

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... 11, 2017 NXT-ID, Inc. (NASDAQ:   ... announces the appointment of independent Directors Mr. Robin D. ... Board of Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , ... forward to their guidance and benefiting from their considerable expertise ...
(Date:4/5/2017)... YORK , April 5, 2017 Today ... is announcing that the server component of the HYPR ... known for providing the end-to-end security architecture that empowers ... HYPR has already secured over 15 million ... makers including manufacturers of connected home product suites and ...
(Date:4/3/2017)... , April 3, 2017  Data ... precision engineering platform, detected a statistically significant ... product prior to treatment and objective response ... the potential to predict whether cancer patients ... to treatment, as well as to improve ...
Breaking Biology News(10 mins):
(Date:9/20/2017)... ... September 20, 2017 , ... The ... Agronomic Services (Koch) to feature new innovations aimed at helping farmers solve the ... 2018. American Farmer airs Tuesdays at 8:30aET on RFD-TV. Check your local listings ...
(Date:9/20/2017)... ... September 20, 2017 , ... ... a study examining the effects of exoskeleton-assisted walking on gait parameters and ... The article, "Neuromechanical adaptations during a robotic powered exoskeleton assisted walking session" ...
(Date:9/19/2017)... ... September 19, 2017 , ... Participants of this ... high-performance fume hood. Along with the advantages and disadvantages of ductless, filtered fume ... hoods in the laboratory. , Attendees will learn from an industry expert about ...
(Date:9/19/2017)... 19, 2017 ValGenesis Inc., the global leader ... to announce the strategic partnership with VTI Life Sciences ... validation services using the latest technology available in the ... clients with efficient and cost-effective validation services using ValGenesis ... the ValGenesis VLMS system. ...
Breaking Biology Technology:
Cached News: