HOME >> BIOLOGY >> NEWS
New designer lipid-like peptide with lipid nanostructures for drug delivery systems

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Peptide Surfactants in the May 30th issue of the online, open-access journal PLoS ONE. Their findings not only help us to understand the basic science of how lipid-like peptides interact with lipid molecules, but also may provide new strategies for the encapsulation and the delivery of biological active materials. They detailed their findings in the report on the impact of integrating short surfactant-like designer peptides in lipidic nanostructures.

Anan Yaghmur, Michael Rappolt, Peter Laggner and Shuguang Zhang reported the formations of dynamic nanostructures of lipid-like peptides that are like two-headed Janus, both water-loving and water-hating, which represent a new class of designer materials using common amino acids, the same basic molecules from meat, beans and fruits. These lipid-like peptides have excellent potential to solubilize membrane proteins and enzymes, and - as now demonstrated - can also be utilized to stabilize different self-assembled liquid crystalline nanostructures. Moreover, the surface charge density of lipidic nanostructures can be varied in a simple manner.

Dr. Anan Yaghmur, first author of the study, comments on the study, the addition of small amounts of designer lipid-like peptides is sufficient to form systems with excellent potential for various biotechnological applications such as the encapsulation of water-insoluble drugs and the delivery of biological active materials.

Currently, many anticancer drugs are difficult to deliver to patients due to their difficulty to be soluble in water. This is a systematic study to combine with lipid molecules, Shuguang Zhang of MIT, a co-author said, people have b
'"/>

Contact: Anan Yaghmur
anan.yaghmur@oeaw.ac.at
Public Library of Science
29-May-2007


Page: 1 2

Related biology news :

1. Tailored treatments: Promising designer drug provides new insight into cancer biology
2. Two designer drugs hit same lung cancer target, but only one is effective
3. Mouse with designer liver has enhanced glucose tolerance and improved insulin response
4. Urban ecology study witnessing the birth of a designer ecosystem
5. New NIST reference material for peptide analysis
6. UCLA AIDS Institute researchers find a peptide that encourages HIV infection
7. Therapeutic peptide frees the protein p73 to kill tumor cells
8. Synthetic peptide targets latent papilloma virus infections
9. Scientists identify 36 genes, 100 neuropeptides in honey bee brains
10. Defense peptide found in primates may block some human HIV transmissions
11. Patent awarded for LSUHSC-developed peptide that blocks lethal toxins of anthrax

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/1/2019)... ... ... The GENSPEED platform is a compact, fast and simple system to enable ... 100 units deployed in the field for multiple applications. “Beyond the creation of ... give us a foothold in the USA to better support other nascent test development ...
(Date:8/1/2019)... ... July 31, 2019 , ... Molecular Devices, LLC, a leader ... generation of its FLIPR® Penta High-Throughput Cellular Screening System. , The new FLIPR ... of G-protein-coupled receptors (GPCRs) and ion channels, offering a new high-speed camera option ...
(Date:7/26/2019)... ... July 26, 2019 , ... Worldwide Business with ... Technologies CEO Phil Deschamps to discuss their potential new treatment option to manage ... a neurotech company in the medical device industry that's focused on neurological wellness. ...
Breaking Biology News(10 mins):
(Date:7/30/2019)... ... 2019 , ... The summer season has been super busy ... has the company already hosted many of its signature cooking classes and team-building ... , With Lajollacooks4u’s Private Cooking Parties, guests prepare and enjoy a variety of ...
(Date:7/17/2019)... (PRWEB) , ... July 15, 2019 , ... CRISPR is ... that a certain trait can be removed, replaced, or edited, but Yiping Qi, assistant ... far beyond these traditional applications in his latest publication in Nature Plants. In this ...
(Date:7/9/2019)... , ... July 08, 2019 , ... ... The company’s SmartLight Indicator was recognized as the 2019 Innovative Product of the ... forward. The prestigious awards were during Sensors Expo & Conference 2019, ...
(Date:6/12/2019)... (PRWEB) , ... June 12, 2019 , ... ... built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, Medical Device and Food ... Zillion has been signed. The agreement will grant exclusive rights for Zillion to ...
Breaking Biology Technology:
Cached News: