The Latest Biology News And Medical NewsBiology News 2Health News 2Biology News 3Health News 3
HOME >> BIOLOGY >> NEWS
New designer lipid-like peptide with lipid nanostructures for drug delivery systems

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Peptide Surfactants in the May 30th issue of the online, open-access journal PLoS ONE. Their findings not only help us to understand the basic science of how lipid-like peptides interact with lipid molecules, but also may provide new strategies for the encapsulation and the delivery of biological active materials. They detailed their findings in the report on the impact of integrating short surfactant-like designer peptides in lipidic nanostructures.

Anan Yaghmur, Michael Rappolt, Peter Laggner and Shuguang Zhang reported the formations of dynamic nanostructures of lipid-like peptides that are like two-headed Janus, both water-loving and water-hating, which represent a new class of designer materials using common amino acids, the same basic molecules from meat, beans and fruits. These lipid-like peptides have excellent potential to solubilize membrane proteins and enzymes, and - as now demonstrated - can also be utilized to stabilize different self-assembled liquid crystalline nanostructures. Moreover, the surface charge density of lipidic nanostructures can be varied in a simple manner.

Dr. Anan Yaghmur, first author of the study, comments on the study, the addition of small amounts of designer lipid-like peptides is sufficient to form systems with excellent potential for various biotechnological applications such as the encapsulation of water-insoluble drugs and the delivery of biological active materials.

Currently, many anticancer drugs are difficult to deliver to patients due to their difficulty to be soluble in water. This is a systematic study to combine with lipid molecules, Shuguang Zhang of MIT, a co-author said, people have b
'"/>

Contact: Anan Yaghmur
anan.yaghmur@oeaw.ac.at
Public Library of Science
29-May-2007


Page: 1 2

Related biology news :

1. Tailored treatments: Promising designer drug provides new insight into cancer biology
2. Two designer drugs hit same lung cancer target, but only one is effective
3. Mouse with designer liver has enhanced glucose tolerance and improved insulin response
4. Urban ecology study witnessing the birth of a designer ecosystem
5. New NIST reference material for peptide analysis
6. UCLA AIDS Institute researchers find a peptide that encourages HIV infection
7. Therapeutic peptide frees the protein p73 to kill tumor cells
8. Synthetic peptide targets latent papilloma virus infections
9. Scientists identify 36 genes, 100 neuropeptides in honey bee brains
10. Defense peptide found in primates may block some human HIV transmissions
11. Patent awarded for LSUHSC-developed peptide that blocks lethal toxins of anthrax

Post Your Comments:
(Date:11/23/2009)... November 16, 2009 -- A USDOE and USDA study concl...cropland, and cropland pasture could be converted ...rasses, such as switchgrass, from which biomass co...conomically viable production of a perennial grass...biomass are removed annually is expected to requir...
(Date:11/23/2009)...H. University of New Hampshire microbiologist Lou...to advance understanding of the actinorhizal plant...h nutrient-poor and contaminated soils. , The U...ded Tisa, a professor of molecular, cellular and b...tic relationship between the bacteria Frankia and ...
(Date:11/23/2009)... of Southern California biomedical engineer and ca...ew tool to help clinicians distinguish cardiac eme...problems manageable with drugs and lifestyle chang...ed into the arteries feeding the heart, offer an i...ese blood vessels, often revealing deposits of a d...
Breaking Biology News(10 mins):Switchgrass produces biomass efficiently 2UNH prof. receives nearly $500,000 to research environmentally significant plants 2Stable plaque or heart attack plaque? USC researcher builds new sensor to tell which is which 2Circumcision Doesnt Lessen HIV Transmission 51973 1Circumcision Doesnt Lessen HIV Transmission 51973 2Auroras Milwaukee Hospitals Recognized in US News and World Report 51970 1Auroras Milwaukee Hospitals Recognized in US News and World Report 51970 2The Mount Sinai Medical Center Named to 26quot 3BHonor Roll 26quot 3B in U S News 26apos 3Bs 2009 10 Edition of America 26apos 3Bs Best Hospitals 51968 1The Mount Sinai Medical Center Named to 26quot 3BHonor Roll 26quot 3B in U S News 26apos 3Bs 2009 10 Edition of America 26apos 3Bs Best Hospitals 51968 2The Mount Sinai Medical Center Named to 26quot 3BHonor Roll 26quot 3B in U S News 26apos 3Bs 2009 10 Edition of America 26apos 3Bs Best Hospitals 51968 3
(Date:11/25/2009)...--ArdeaBiosciences,Inc.(Nasdaq: RDEA )announcedtod...tiveofficer,willpresentatthePiperJaffray21stAnnual...follows:,PiperJaffray21stAnnualHealthCareConferen...nTime,Location:TheNewYorkPalaceHotel,NewYork,NY,We...target=,_blank,title=,http://www.corporate-ir.net/...
(Date:11/24/2009)...-IES(Nasdaq: IESC ),aleadingnationalproviderofelec...mercial,industrialandresidentialmarkets,announcedt...ontractfromManhattanTorconJVtoinstalltheelectrical...facilityattheU.S.ArmyMedicalResearchInstituteofInf...Md. ,, ThenewUSAMRIIDreplacementfacilitywilladd...
(Date:11/24/2009)...ment bank KTA Capital,s client Neuren Pharmaceutic...ible note private placement with a U.S. institutio...y KTA Capital as Neuren,s exclusive placement agen... (PRWEB) November 23, 2009 -- The independent New ...apital") has announced that its client Neuren...
(Date:11/24/2009)...ewswire-FirstCall/--DowAgroSciencesCanadaannounced...ofThompsonsLimitedofBlenheim,Ontario.Theadditionof...tseedsbusinessasthecompanyanticipatestheintroducti...bicideTolerantTraitTechnologyincornin2012.Thetrans...sacquisitionbringstogethertwostrongprogressivecomp...
Breaking Biology Technology:Ardea Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference 2Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases 2KTA Capital Arranges an AU$6.7 Million Private Placement by Neuren Pharmaceuticals 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 2Dow AgroSciences Canada Announces Agreement to Acquire Hyland Seeds 3
Other News:
Aging flies are simply crawling with bacteriaboth inside and outbut their microbial infestations dont seem to hasten the insects toward death, according to a new study in the August issue of the journ
...logist Curt Stager of Paul Smith's College in Paul...c health officials to increase measures against in...he results are published online in the August 7 is... scientists showed that unusually heavy rainfalls ...
...efit on Liver Cancer Death Rates... Taking vitamin...ates in a study conducted by the National Cancer I...es. ... Liver cancer is a common cancer with a hig... to reduce the number of deaths from the disease. ...
...it wont do you any good, according to a study of f...ologists.... Flies scrubbed clean of bacteria did ... report in the August 8 issue of Cell Metabolism.....that even harmless bacteria and the immune respon...
In limiting life span, study finds booming bacteria innocent 2Link between sunspots, rain helps predict disease in east Africa 2Other highlights in the Aug. 7 JNCI 2Other highlights in the Aug. 7 JNCI 3Bacteria may not hasten death 2
Tampa, FL (June 27, 2003) -- The buildup of Alzheimer's-associated amyloid plaques in the brain dramatically inhibits several genes critical to memory and learning, University of South Florida College
...TON, Va. -- On topics ranging from mutant mice for....S.-European Commission (EC) Task Force on Biotech...arch bridging the Atlantic.......At the meetings, ...erday and Wednesday, a new potential for trans-Atl...
..., Spain: New research indicates that attempts to m...a stumbling block unless better 'growing' conditio...tility experts has revealed for the first time tha...the very earliest stages of egg follicle developme...
..., Spain: Research by Spanish fertility experts is ...omplication of assisted reproduction ovarian hype...est form, which requires urgent medical treatment,...pain and as many as 2,000 a year in Europe. OHSS o...
Study links amyloid plaques in Alzheimer's brains to genes vital to normal memory 2Study links amyloid plaques in Alzheimer's brains to genes vital to normal memory 3US-EC Biotech Task Force keys on research, collaboration 2US-EC Biotech Task Force keys on research, collaboration 3First evidence that genetic imprinting occurs at earliest stage in test tube-matured eggs 2First evidence that genetic imprinting occurs at earliest stage in test tube-matured eggs 3Spanish fertility experts bring hope of avoiding serious complication of assisted reproduction 2