New grants bolster efforts to generate faster and cheaper tools for DNA sequencing

tional grants aim to make improvements that could be implemented in the near future to further improve sequencing at this dramatically-lowered cost. Grant recipients and their approximate total funding are:

  • Jeremy S. Edwards, Ph.D. , University of New Mexico School of Medicine, Albuquerque
    $900,000 (3 years)
    Polony Sequencing the Human Genome

The ultimate goal of this team is to use established polony genome sequencing technology to re-sequence a human genome within a week for less than $10,000. To meet their goal, they will continue improving the quality of sequencing data and further develop the computational tools needed to assemble a human genome sequence.

  • Jingyue Ju, Ph.D., Columbia University, New York (Two Grants)
    $644,000 (2 years)
    3-O-Modified Nucleotide Reversible Terminators for Pyrosequencing

This investigator will design a library of synthetic molecular tools designed to optimize the pyrosequencing method to overcome the difficulties deciphering repetitive regions of DNA templates. The current pyrosequencing method utilizes unmodified DNA base pairs and polymerases to synthesize DNA and a firefly enzyme to generate a chemiluminescent signal.

  • Jingyue Ju, Ph.D., Columbia University, New York
    $2,217,000 (2 years)
    An Integrated System for DNA Sequencing by Synthesis

This team will continue its development and optimization of a novel set of fluorescent nucleotide reversible terminators for sequencing by synthesis. A new method for preparing DNA-beads for attachment to a substrate will also be developed. The goal is to increase the length of the DNA sequencing reads while maintaining high data quality.

  • David C. Schwartz, Ph.D., University of Wisconsin, Madison
    $882,000 (3 years)
    Sequence Acquisition from Mapped Single DNA Molecules

The focus of this project is to create a system

Contact: Geoff Spencer
NIH/National Human Genome Research Institute

Page: 1 2 3 4 5 6

Related biology news :

1. Gilbert Foundation and American Fed for Aging Research award grants on Alzheimers disease
2. New amfAR research grants to optimize HIV treatment
3. Ancient Etruscans were immigrants from Anatolia, or what is now Turkey
4. Berkeley Lab Life Sciences division awarded NIH grants for fruit fly, nematode studies
5. UAF researchers garner $6.5 million in NSF grants
6. Burroughs Wellcome fund awards $8.25 million in grants to physician-scientists
7. UCLA scientists garner 7 grants to fund leading-edge embryonic stem cell research
8. New medications, cancer diagnosis goals of UH engineers with $1M in grants
9. Barrow receives two grants worth a total of 900,000 from the ABRC
10. Kentucky first state to match federal SBIR-STTR Phase 1 and Phase 2 grants
11. NSF awards 17 grants for research on biocomplexity in the environment

Post Your Comments:

(Date:8/12/2020)... ... 2020 , ... Both Roche, based in Basel, Switzerland, and ... with Housey Pharma’s HMI subsidiary to gain access to its core-enabling technology for ... Development spending in excess of US $10 billion. , Scientists at Housey Pharma ...
(Date:8/3/2020)... ... August 03, 2020 , ... Accumen Inc. ... with medical equipment manufacturer, Spectrum Solutions, to provide COVID-19 saliva testing kits nationally. ... supply chain for more than 10 years. Early in the COVID-19 crisis, we ...
(Date:7/18/2020)... ... 17, 2020 , ... Commercial launch readiness is a critical stage in a ... cure or vaccine, the global economic downturn will only increase price pressures overall for ... and capturing full value from every product launch is critical. However, history shows that ...
Breaking Biology News(10 mins):
(Date:8/7/2020)... ... August 06, 2020 , ... ... announces it has closed on the purchase of greenfield for a new, expanded ... and includes over 21 acres in the initial acquisition, with an option to ...
(Date:7/31/2020)... ... ... R3 Stem Cell International is now offering patients the opportunity to receive four ... may choose which extremities they would like treated. , Several studies have shown just ... R3 International, umbilical cord tissue is obtained from a lab with a long history ...
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet Products has introduced ... materials for use with CRM, neurostimulation, vascular, and related devices. , Anomet ... design requirements, performance, and cost criteria; especially where solid wire is limited. Typical ...
(Date:7/31/2020)... ... July 29, 2020 , ... ... the top radiation centers in 16 countries, has reached its 20th anniversary of ... now in routine use at top universities including University of Pennsylvania, University of ...
Breaking Biology Technology:
Cached News: