HOME >> BIOLOGY >> NEWS
New insight about the source of anxiety in Rett syndrome

icotropin-releasing hormone) plays a critical role in the stress response that produces anxiety in these children, governing in part the production of stress hormones. In humans, the major one of these is cortisol. In mice, it is corticosterone.

They chose anxiety because it has been well studied, and its molecular basis is partially understood. They found that the Rett mice suffered from serious anxiety and that in a stressful situation, they produced 1.5 times the amount of corticosterone produced by normal mice.

They propose that normally, MeCP2 acts like a rheostat that controls CRH and thus the stress response, depending on the need of the situation. CRH kicks the response up. When MeCP2 is mutated, this process is less controlled.

Currently, some anti-anxiety drugs are being developed that block the receptor for CRH on the cell. McGill, Zoghbi, and their colleagues are studying the effect of these drugs on the animals with the mutated MeCP2 gene.


'"/>

Contact: Ross Tomlin
htomlin@bcm.edu
713-798-4710
Baylor College of Medicine
13-Nov-2006


Page: 1 2

Related biology news :

1. Genomics study provides insight into the evolution of unique human traits
2. Scientists gain important insights into acute promyelocytic leukemia
3. Variant CJD -- Prion amplification breakthrough brings new insights and hopes for a blood test
4. Largest synthetic gene ever built offers insights into anti-malarial drug resistance
5. New insights into the neural basis of anxiety
6. Study of protein folds offers insight into metabolic evolution
7. From ink to optics, study of particle mixtures yields fundamental insights
8. Understanding the global carbon budget -- Woods Hole Research Center expert provides insights
9. Study of damaged gene gives insight into causes of mental illness
10. A rainbow of methods promises insights into biological processes and diseases
11. Study of planarians offers insight into germ cell development

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/11/2019)... WEST LAFAYETTE, Ind. (PRWEB) , ... June 10, 2019 , ... ... Synchrotron Methods” in the July 2019 issue of AAPS PharmSciTech. The article was published ... A. Smith of Improved Pharma, along with Xiaoming Sean Chen of Purdue University. ...
(Date:6/4/2019)... ... June 04, 2019 , ... ... orthopedic medical devices, today announced Q1-19 revenues of $31M, up 12% from Q1-18. ... successful roll-out of strategic investments & operational excellence initiatives worldwide. , Laurent ...
(Date:6/4/2019)... ... 2019 , ... Lajollacooks4u is delighted to announce it has been named as ... is given only to businesses that have achieved consistently outstanding traveler reviews on TripAdvisor, ... , To qualify for the Certificate of Excellence –- an award that only 10 ...
Breaking Biology News(10 mins):
(Date:6/11/2019)... (PRWEB) , ... June 11, 2019 , ... ... of Personalized Stem Cells Inc. (PSC) , has announced that their GMP ... Health, Food and Drug Branch for manufacturing. This is an important milestone ...
(Date:6/6/2019)... ... June 05, 2019 , ... WCCT Global, Inc ., a full-service ... today that they will be receiving 3 awards at the 2019 CRO Leadership Awards, ... awards in the categories of overall Quality and Compatibility (Access to desired markets, cultural ...
(Date:5/31/2019)... Redwood City, California (PRWEB) , ... ... ... received allowance of our patent applications from the USPTO providing proprietary interest ... SYSTEM AND METHOD FOR SLEEP DISORDER DIAGNOSIS AND TREATMENT… extends Somnology’s IP ...
(Date:5/31/2019)... NEWPORT BEACH, Calif. (PRWEB) , ... May 30, ... ... the future of neurotoxins, is pleased to announce the strategic acquisition of Metabiologics, ... for research. The acquisition provides Object exclusive ownership and commercialization rights to a ...
Breaking Biology Technology:
Cached News: