HOME >> BIOLOGY >> NEWS
New joint replacement material developed at MGH put to first clinical use

Massachusetts General Hospital (MGH) surgeons have performed the first total hip replacement using a joint socket lined with a novel material invented at the MGH. An advance over first-generation highly crosslinked polyethylene, which was also developed at MGH and significantly reduced a serious complication of early hip implants, the new material may be applied in replacements for a wider variety of joints in a more diverse group of patients.

We think this material could be used for any joint in the body and in any implant design, even those demanding higher flexion and more mobility, says Orhun Muratoglu, PhD, co-director of the Harris Orthopdics Biomechanics and Biomaterials Laboratory (OBBL) at MGH, who developed the new material in collaboration with scientists at the Cambridge Polymer Group.

Total replacements for hips and other joints were developed in the late 1960s, but it soon became apparent that hip implants could start loosening about 5 years after surgery and would eventually fail completely. A team led by William Harris, MD, DSc, now director emeritus of the MGH OBBL, investigated this complication and found that long-term friction of the implants head against the polyethylene-lined joint socket would break off small particles of polyethylene. The bodys immune system reacted against these foreign particles, eventually destroying adjacent bone tissue and causing the implant to loosen a condition called periprosthetic osteolysis.

Harris and his colleagues, working with polymer chemists from MIT, found that high doses of radiation would crosslink the polyethylene, bonding molecules together to produce a much more durable material. The procedure also generates free radicals that could lead to oxidization and degradation of the implant, but the research team found that melting the material would eliminate free radicals. The first-generation highly crosslinked polyethylene was approved by the FDA for use in implants
'"/>

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
23-Jul-2007


Page: 1 2

Related biology news :

1. It takes a village -- female ducks negotiate joint rearing of ducklings
2. Brown and OTS will jointly manage new ILTER network secretariat
3. How movement lubricates bone joints
4. Gene therapy research switches off joint inflammation; switches on genetic process of joint repair
5. New evidence shows Rituximab halts damage to joints
6. Healthy fruits, vegetables highlight joint medical, agricultural research meet in Texas
7. Brookhaven Lab and Mount Sinai form joint Center for Translational Biomedical Imaging
8. Biodesign and TGen form joint Center for Systems and Computational Biology
9. $1 million grant from Howard Hughes Medical Institute to fund joint neuroscience program
10. Phytochemicals may protect cartilage, prevent pain in joints
11. UCSD medical/bioengineering reseachers show titanium debris satobtage artificial joints

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... subsidiary of Infosys (NYSE: INFY ), and Samsung ... global partnership that will provide end customers with a ... and payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ... for financial services, but it also plays a fundamental part ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
(Date:4/15/2016)... April 15, 2016 Research ... Gait Biometrics Market 2016-2020,"  report to their offering.  ... ) , ,The global gait biometrics market is ... during the period 2016-2020. Gait analysis ... can be used to compute factors that are ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... ... May 03, 2016 , ... ... NYC , the sensor and data driven conferences, will take place on June 7-8, 2016, at ... UnitedHealth's Vidya Raman-Tangella on incorporating technology -- including AR/VR, machine learning, apps, robotics ...
(Date:5/3/2016)... ... 2016 , ... According to world renowned prostate cancer surgeon, Dr. David ... had two main treatment options: surgery or radiation. Based on a patient’s goals, disease ... has enabled doctors to administer higher doses of radiation to prostate cancer ...
(Date:5/2/2016)... ... May 02, 2016 , ... Meister Media ... the fresh look and added functionality give the agricultural world a taste of ... dynamic shift in agriculture – from precision farming via satellites and Unmanned Aerial ...
(Date:4/29/2016)... ... April 30, 2016 , ... The MIT bioLogic design ... the bioLogic team explored how bacterial properties can be applied to fabric and formed ... bacteria, which move in response to humidity change. The team harvested Natto cells and ...
Breaking Biology Technology:
Cached News: