HOME >> BIOLOGY >> NEWS
New microscope allows scientists to track a functioning protein with atomic-level precision

A Stanford University research team has designed the first microscope sensitive enough to track the real-time motion of a single protein down to the level of its individual atoms. Writing in the Nov. 13 online issue of the journal Nature, the Stanford researchers explain how the new instrument allowed them to settle long-standing scientific debates about the way genes are copied from DNA--a biochemical process that's essential to life.

In a second paper published in the Nov. 8 online issue of the journal Physical Review Letters, the scientists offer a detailed description of their novel device, an advanced version of the "optical trap," which uses infrared light to trap and control the forces on a functional protein, allowing researchers to monitor the molecule's every move in real time.

"In the Nature experiment, we carried out the highest-resolution measurement ever made of an individual protein," says Steven Block, professor of applied physics and of biological sciences. "We obtained measurements accurate to one angstrom, or one-tenth of a nanometer. That's a distance equivalent to the diameter of a single hydrogen atom, and about 10 times finer than any previous such measurement."

Block co-authored the papers in Nature and Physical Review Letters with three current members of his Stanford Lab--graduate students Elio Abbondanzieri and William Greenleaf and postdoctoral fellow Michael Woodside--together with former graduate student Joshua Shaevitz, now at the University of California-Berkeley, and longtime collaborator Robert Landick at the University of Wisconsin.

Central dogma

In the Nature study, Block and his colleagues tackled a fundamental principal of biology known as the central dogma, which states that in living organisms, genetic information flows from DNA to RNA to proteins.

The process begins with DNA, the famous double helix, which stores genetic data. DNA is often compared to a twisted ladder co
'"/>

Contact: Mark Shwartz
mshwartz@stanford.edu
650-723-9296
Stanford University
13-Nov-2005


Page: 1 2 3 4 5 6 7

Related biology news :

1. Rensselaer licenses microscope technology to Thorlabs
2. Nanoscale microscope sheds first light on gene repair
3. New light microscope may help unlock some of cells secrets
4. New light microscope sharpens scientists focus
5. New, unique microscope for nanotech
6. Study using robotic microscope shows how mutant Huntingtons protein affects neurons
7. Presence of wolves allows aspen recovery in Yellowstone
8. Cannibalism of the young allows individual fish to specialize
9. Social tolerance allows bonobos to outperform chimpanzees on a cooperative task
10. Expedition allows teachers to participate in polar research
11. Remarkable physiology allows crucian carp to survive months without oxygen

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/7/2020)... ... 2020 , ... Nine middle school teachers from eight states ... unique professional development program that provides advanced STEM (science, technology, engineering and math) ... , Created in partnership between the National Stem Cell Foundation and The Gatton ...
(Date:7/31/2020)... FRANCISCO (PRWEB) , ... July 30, 2020 , ... ... maturing prescription digital therapeutics product portfolio with a near term focus on Type ... biotech and pharma commercialization experience across multiple therapeutic areas and classes. As Chief ...
(Date:7/10/2020)... Va. (PRWEB) , ... July 08, 2020 , ... ... Latest on Cell and Gene Therapy Regulation, An FDAnews Webinar, Wednesday, July 22, ... need a comparability study, but what is the most effective way to complete ...
Breaking Biology News(10 mins):
(Date:8/3/2020)... ... August 03, 2020 , ... ... announced Jim Corrigan, President and CEO has been named one of the 100 ... of industry sectors, PharmaVoice 100 honorees are selected based on how they have ...
(Date:7/31/2020)... ... July 29, 2020 , ... Anomet ... to three different materials for use with CRM, neurostimulation, vascular, and related devices. ... to meet specific design requirements, performance, and cost criteria; especially where solid wire ...
(Date:7/22/2020)... ... ... Join experts from Reed Tech , Gary Saner, Sr. Manager, Information Solutions ... live webinar on Thursday, August 13, 2020 at 11am EDT (4pm BST/UK). , ... for medical devices, the NMPA has departments dealing with medical device registration (pre-market approvals) ...
(Date:7/10/2020)... LORTON, Va. (PRWEB) , ... July 08, 2020 ... ... laboratory testing services and products, announces a significant expansion of laboratory operations through ... robust collection for agencies implementing testing programs. , Bode-CARES provides ...
Breaking Biology Technology:
Cached News: