HOME >> BIOLOGY >> NEWS
New reference material for diagnosing kidney disease

The National Institute of Standards and Technology (NIST) has developed a new reference material to help improve the accuracy of clinical diagnostic tests for chronic kidney disease. The new Standard Reference Material (SRM) consists of samples of frozen human blood serum certified by NIST for two different concentrations of creatinine.

Chronic kidney disease (CKD) is a growing problem in the United States. It can be caused by high blood pressure, diabetes and other disorders. If left untreated, it eventually can lead to kidney failure. The National Kidney Disease Outcome Quality Initiative* reported that end-stage renal disease has dramatically increased in the past two decades, and estimated that close to 20 million Americans probably have early stages of CKD.

Timely diagnosis is a significant problem. Kidney function is measured by glomerular filtration rate (GFR), which provides an estimate of how well the kidneys are removing waste and excess fluid from the blood. GFR cannot be measured directly in a clinical setting, so instead physicians test for blood serum levels of creatinine, a metabolic by-product of muscles. Plugging the creatinine level into an equation that factors in other variables, including age, gender and race, yields an estimated GFR value. Detecting relatively small changes in serum creatinine levels is key to early diagnosis of CKD, but studies summarized in a recent paper** from the National Kidney Disease Education Program (NKDEP, an initiative of the National Institutes of Health) noted that the current variability in serum creatinine measurements is too large to detect small increases in creatinine.

The new NIST SRM 967, Creatinine in Frozen Human Serum, was developed in collaboration with the NKDEP and the College of American Pathologists (CAP) to meet the need for improved calibration of clinical instruments and procedures for measuring serum creatinine. The SRM consists of frozen human serum with two di
'"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
16-Mar-2007


Page: 1 2

Related biology news :

1. Dietary preferences and patterns may be linked to genes
2. New NIST reference material for peptide analysis
3. New edition of touchstone microbiology reference book now available
4. Human preference for other species could determine whether they survive
5. How sweet it isnt -- preference for alternatives to sugar based on sour, bitter tastes
6. NIST seeks reference nucleic acid sequences
7. Salty taste preference linked to birth weight
8. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
9. Study finds colony size selection determines adult survival and dispersal preferences in kestrels
10. Certain fish have a special mating preference
11. New NIST reference material reinforces fragile-x screens

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New reference material for diagnosing kidney disease

(Date:3/20/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/rswjb4/hand_geometry ) has announced ... Business Report" report to their offering. This ... Thousands. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the ...
(Date:3/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/vkzvcs/iris_biometrics ) has ... Strategic Business Report" report to their offering. ... US$ Thousands. The report provides separate comprehensive analytics for the ... , Europe , Asia-Pacific ... Latin America . Annual estimates and forecasts ...
(Date:3/18/2015)... , March 18, 2015 As ... businesses, new revolutionary smart wallets and apps continue to be ... currently entrenched in the mobile payment industry in focus today ... Holding Ltd. (NYSE: BABA ), Apple Inc. (NASDAQ: ... ) and Facebook Inc. (NASDAQ: FB ) ...
Breaking Biology News(10 mins):Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 2Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 3Hand Geometry - Global Strategic Business Report 2015: An Essential Security Component for both Government & Enterprise Sector 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6
(Date:4/27/2015)... Kan. , April 27, 2015   ... a pet therapeutics company focused on the licensing, ... companion animals, today provided commentary on clinical study ... during a poster session at the American Association ... ADXS31-164 is a novel Lm -LLO ...
(Date:4/27/2015)... DryLet, LLC a biotechnology company ... as animal waste reduction, bioremediation, wastewater treatment, aquaculture ... treatment plants and restaurant kitchen settings, announced today ... Commission on Environmental Quality (TCEQ) Environmental Trade Fair ... The company will highlight three of its key ...
(Date:4/27/2015)... , April 27, 2015  Together with its ... 3rd ESTRO Forum in Barcelona . ... nonprofit organization with the mission to improve cancer care, ... Radiating Hope believes that no patient should be denied ... affordable. Consequently, it cooperates with hospitals and clinics around ...
(Date:4/24/2015)... City, SD and Tempe, AZ (PRWEB) April 24, 2015 ... & Technology and Arizona State University (ASU) have entered ... other joint projects. , A memorandum of agreement signed ... research, long distance learning, student success and other services ... natural resources. , “We have complementary strengths and ...
Breaking Biology Technology:Aratana Therapeutics Comments on ADXS31-164 (AT-014) Study Data Presented During Poster Session at the American Association for Cancer Research (AACR) Annual Meeting 2015 2DryLet to Showcase Multiple Products at Texas Commission on Environmental Quality Trade Fair and Conference May 5-6 in Austin, Texas 2Elekta helps raise $33,000 to bring radiation treatment to developing countries 2Elekta helps raise $33,000 to bring radiation treatment to developing countries 3South Dakota Mines, Arizona State University Pave Way for Cooperative Research 2
Cached News: