HOME >> BIOLOGY >> NEWS
New reference material for diagnosing kidney disease

The National Institute of Standards and Technology (NIST) has developed a new reference material to help improve the accuracy of clinical diagnostic tests for chronic kidney disease. The new Standard Reference Material (SRM) consists of samples of frozen human blood serum certified by NIST for two different concentrations of creatinine.

Chronic kidney disease (CKD) is a growing problem in the United States. It can be caused by high blood pressure, diabetes and other disorders. If left untreated, it eventually can lead to kidney failure. The National Kidney Disease Outcome Quality Initiative* reported that end-stage renal disease has dramatically increased in the past two decades, and estimated that close to 20 million Americans probably have early stages of CKD.

Timely diagnosis is a significant problem. Kidney function is measured by glomerular filtration rate (GFR), which provides an estimate of how well the kidneys are removing waste and excess fluid from the blood. GFR cannot be measured directly in a clinical setting, so instead physicians test for blood serum levels of creatinine, a metabolic by-product of muscles. Plugging the creatinine level into an equation that factors in other variables, including age, gender and race, yields an estimated GFR value. Detecting relatively small changes in serum creatinine levels is key to early diagnosis of CKD, but studies summarized in a recent paper** from the National Kidney Disease Education Program (NKDEP, an initiative of the National Institutes of Health) noted that the current variability in serum creatinine measurements is too large to detect small increases in creatinine.

The new NIST SRM 967, Creatinine in Frozen Human Serum, was developed in collaboration with the NKDEP and the College of American Pathologists (CAP) to meet the need for improved calibration of clinical instruments and procedures for measuring serum creatinine. The SRM consists of frozen human serum with two di
'"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
16-Mar-2007


Page: 1 2

Related biology news :

1. Dietary preferences and patterns may be linked to genes
2. New NIST reference material for peptide analysis
3. New edition of touchstone microbiology reference book now available
4. Human preference for other species could determine whether they survive
5. How sweet it isnt -- preference for alternatives to sugar based on sour, bitter tastes
6. NIST seeks reference nucleic acid sequences
7. Salty taste preference linked to birth weight
8. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
9. Study finds colony size selection determines adult survival and dispersal preferences in kestrels
10. Certain fish have a special mating preference
11. New NIST reference material reinforces fragile-x screens

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2017)... About Voice Recognition Biometrics Voice recognition biometrics ... a stored voiceprint template. Acoustic features of an ... are compared to distinguish between individual voices. Voice ... PCs already have a microphone and can authenticate ... are most likely to be deployed in telephone-based ...
(Date:2/8/2017)... YORK , Feb. 7, 2017 ... Driven largely by the confluence of organizations, desires ... distaste for knowledge-based systems (password and challenge questions), ... industrial, and government systems. The market is driven ... a demarcation between consumer and enterprise uses cases, ...
(Date:2/7/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ... at the LEERINK Partners 6th Annual Global Healthcare Conference ... February 15, 2017 at 10 a.m. Eastern Time. ... be accessed at http://wsw.com/webcast/leerink28/zbh .  The webcast will ... Biomet,s Investor Relations website at http://investor.zimmerbiomet.com . ...
Breaking Biology News(10 mins):
(Date:2/23/2017)... - The Fight Against Cancer Innovation Trust (FACIT) and ... to report that Fusion Pharmaceuticals Inc. (Fusion) has closed ... Innovation – JJDC, Inc. (JJDC) as the lead investor. ... Partners, and Genesys Capital, as well as founding investor ... ...
(Date:2/23/2017)... ... February 23, 2017 , ... Brain Sentinel, Inc. has received ... SPEAC® System, the Brain Sentinel® Seizure Monitoring and Alerting System. The adjunctive seizure ... periods of rest. A lightweight, non-invasive monitor is placed on the belly of ...
(Date:2/23/2017)... Feb. 23, 2017  Capricor Therapeutics, Inc. (NASDAQ: CAPR), a ... conditions, today announced that Linda Marbán, Ph.D, president and chief ... conferences: Cowen and Company 37th Annual ... ET Boston, MA ... am PT (12:00 pm ET) Dana Point, CA ...
(Date:2/22/2017)... ANGELES, CA (PRWEB) , ... February 22, 2017 ... ... today announced that is has acquired Kendall Research Systems, LLC (KRS) ... Technology (MIT) that develops neural interface technology for research and clinical applications. The ...
Breaking Biology Technology:
Cached News: