HOME >> BIOLOGY >> NEWS
New reference material for diagnosing kidney disease

The National Institute of Standards and Technology (NIST) has developed a new reference material to help improve the accuracy of clinical diagnostic tests for chronic kidney disease. The new Standard Reference Material (SRM) consists of samples of frozen human blood serum certified by NIST for two different concentrations of creatinine.

Chronic kidney disease (CKD) is a growing problem in the United States. It can be caused by high blood pressure, diabetes and other disorders. If left untreated, it eventually can lead to kidney failure. The National Kidney Disease Outcome Quality Initiative* reported that end-stage renal disease has dramatically increased in the past two decades, and estimated that close to 20 million Americans probably have early stages of CKD.

Timely diagnosis is a significant problem. Kidney function is measured by glomerular filtration rate (GFR), which provides an estimate of how well the kidneys are removing waste and excess fluid from the blood. GFR cannot be measured directly in a clinical setting, so instead physicians test for blood serum levels of creatinine, a metabolic by-product of muscles. Plugging the creatinine level into an equation that factors in other variables, including age, gender and race, yields an estimated GFR value. Detecting relatively small changes in serum creatinine levels is key to early diagnosis of CKD, but studies summarized in a recent paper** from the National Kidney Disease Education Program (NKDEP, an initiative of the National Institutes of Health) noted that the current variability in serum creatinine measurements is too large to detect small increases in creatinine.

The new NIST SRM 967, Creatinine in Frozen Human Serum, was developed in collaboration with the NKDEP and the College of American Pathologists (CAP) to meet the need for improved calibration of clinical instruments and procedures for measuring serum creatinine. The SRM consists of frozen human serum with two di
'"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
16-Mar-2007


Page: 1 2

Related biology news :

1. Dietary preferences and patterns may be linked to genes
2. New NIST reference material for peptide analysis
3. New edition of touchstone microbiology reference book now available
4. Human preference for other species could determine whether they survive
5. How sweet it isnt -- preference for alternatives to sugar based on sour, bitter tastes
6. NIST seeks reference nucleic acid sequences
7. Salty taste preference linked to birth weight
8. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
9. Study finds colony size selection determines adult survival and dispersal preferences in kestrels
10. Certain fish have a special mating preference
11. New NIST reference material reinforces fragile-x screens

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New reference material for diagnosing kidney disease

(Date:12/10/2014)...  Valencell, a leader in performance biometric data sensor ... from its licensees for highly accurate, clinically validated biometric ... coming from fitness and health sectors, but first responders/military ... is only as useful as the biometric data it ... in long-term mass consumer adoption of wearable products," said ...
(Date:12/5/2014)... Calif. , Dec. 4, 2014 ... has boosted investments in new testing and inspection ... also given rise to a range of innovative ... the requirements of Generation Y, which is generally ... As a result, product development strategies of test ...
(Date:11/21/2014)... 18, 2014 According to a ... Systems (Video, RFID, Access Control, Intrusion Detection, Parking Management, ... Government), Component Service Geography - Global Forecasts to 2020", ... projected to be around $25 Billion in 2014 and ... at a CAGR of 8.69%. Browse 116 ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
(Date:12/17/2014)... (PRWEB) December 16, 2014 “Never ... at Philipps- Universität Marburg’s Department of Physics, advises ... in the newly released SPIE Women in ... be too shy to ask questions.” , In ... engineering, and mathematics) occupations ranging from university professor ...
(Date:12/17/2014)... Dallas, Texas (PRWEB) December 17, 2014 ... research on Global Quartz Tubing industry. For an ... information, definition, classification, application, industry chain structure, industry ... domestic quartz tubing industry has witnessed ... through a number of acquisitions. This report mentions ...
(Date:12/17/2014)... AUSTIN, Texas , Dec. 16, 2014  Vermillion, ... company focused on gynecologic disease, today announced the next ... into a premier bio-analytics solutions provider with the naming ... to President and Chief Executive Officer, while current Chairman ... will continue to serve as Chairman. These changes are ...
(Date:12/17/2014)... 2014   Synageva BioPharma Corp. (NASDAQ: ... for rare disorders, announced today its presentation at the ... San Francisco, CA. ... will present on Monday, January 12, 2015, at 9:00 ... webcast live and may be accessed from the "Webcasts ...
Breaking Biology Technology:Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 32020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4
Cached News: