HOME >> BIOLOGY >> NEWS
New reference material for diagnosing kidney disease

The National Institute of Standards and Technology (NIST) has developed a new reference material to help improve the accuracy of clinical diagnostic tests for chronic kidney disease. The new Standard Reference Material (SRM) consists of samples of frozen human blood serum certified by NIST for two different concentrations of creatinine.

Chronic kidney disease (CKD) is a growing problem in the United States. It can be caused by high blood pressure, diabetes and other disorders. If left untreated, it eventually can lead to kidney failure. The National Kidney Disease Outcome Quality Initiative* reported that end-stage renal disease has dramatically increased in the past two decades, and estimated that close to 20 million Americans probably have early stages of CKD.

Timely diagnosis is a significant problem. Kidney function is measured by glomerular filtration rate (GFR), which provides an estimate of how well the kidneys are removing waste and excess fluid from the blood. GFR cannot be measured directly in a clinical setting, so instead physicians test for blood serum levels of creatinine, a metabolic by-product of muscles. Plugging the creatinine level into an equation that factors in other variables, including age, gender and race, yields an estimated GFR value. Detecting relatively small changes in serum creatinine levels is key to early diagnosis of CKD, but studies summarized in a recent paper** from the National Kidney Disease Education Program (NKDEP, an initiative of the National Institutes of Health) noted that the current variability in serum creatinine measurements is too large to detect small increases in creatinine.

The new NIST SRM 967, Creatinine in Frozen Human Serum, was developed in collaboration with the NKDEP and the College of American Pathologists (CAP) to meet the need for improved calibration of clinical instruments and procedures for measuring serum creatinine. The SRM consists of frozen human serum with two di
'"/>

Contact: Michael Baum
michael.baum@nist.gov
301-975-2763
National Institute of Standards and Technology (NIST)
16-Mar-2007


Page: 1 2

Related biology news :

1. Dietary preferences and patterns may be linked to genes
2. New NIST reference material for peptide analysis
3. New edition of touchstone microbiology reference book now available
4. Human preference for other species could determine whether they survive
5. How sweet it isnt -- preference for alternatives to sugar based on sour, bitter tastes
6. NIST seeks reference nucleic acid sequences
7. Salty taste preference linked to birth weight
8. Have a taste for fat? Yes! A sensor in the mouth promotes preference for fatty foods
9. Study finds colony size selection determines adult survival and dispersal preferences in kestrels
10. Certain fish have a special mating preference
11. New NIST reference material reinforces fragile-x screens

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/28/2016)... and BANGALORE, India , April 28, 2016 ... a product subsidiary of Infosys (NYSE: INFY ), ... a global partnership that will provide end customers ... mobile banking and payment services.      (Logo: ... innovation area for financial services, but it also plays a ...
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
(Date:4/15/2016)... -- Research and Markets has announced the ...  report to their offering.  ,      ... gait biometrics market is expected to grow at ... Gait analysis generates multiple variables such ... compute factors that are not or cannot be ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... on a range of subjects including policies, debt and investment ... Speaking at a lecture to the Canadian Economics ... the country,s inflation target, which is set by both the ... "In certain areas there needs to be frequent ... not sit down and address strategy together?" He ...
(Date:6/23/2016)... Seattle, WA (PRWEB) , ... June 23, 2016 ... ... technology, announces the release of its second eBook, “Clinical Trials Patient Recruitment and ... patient recruitment and retention in this eBook by providing practical tips, tools, and ...
(Date:6/23/2016)... A person commits a crime, and the detective ... the criminal down. An outbreak of foodborne illness ... (FDA) uses DNA evidence to track down the bacteria that ... It,s not. The FDA has increasingly used a complex, cutting-edge ... illnesses. Put as simply as possible, whole genome sequencing is ...
(Date:6/23/2016)... 2016  The Biodesign Challenge (BDC), a university competition ... harness living systems and biotechnology, announced its winning teams ... New York City . The ... projects at MoMA,s Celeste Bartos Theater during the daylong ... senior curator of architecture and design, and Suzanne ...
Breaking Biology Technology:
Cached News: