HOME >> BIOLOGY >> NEWS
New research provides evidence that Rh proteins act as CO2 gas channels

Berkeley -- Labels marking bags of donated blood throughout the world contain information about the presence of a Rhesus (Rh) antigen, a protein found on the membranes of human red blood cells. Yet, despite the Rh protein's importance in blood transfusion and the problems it can cause between Rh negative mothers and their Rh positive fetuses, its biological role has remained largely unresolved since its discovery 65 years ago.

But a new study, led by biologists at the University of California, Berkeley, and due to be published June 22 in the journal Genetics, may help clarify the mystery by giving additional evidence that the Rh protein serves as a gas channel for carbon dioxide (CO2).

The study's conclusions, the researchers said, will lead to new directions in human and animal physiology research, as well as generate lively debate among biochemists and hematologists.

"This has implications for understanding how humans breathe, how we control the acidity (pH) of various fluids in our bodies and how our kidneys function, all of which rely upon movement of CO2 across cell membranes," said Sydney Kustu, professor of plant and microbial biology at UC Berkeley's College of Natural Resources and principal investigator of the study.

Kustu noted that scientists had long doubted the presence of protein channels for CO2 or any gases. This is because gases typically have no trouble crossing cell membranes unaided, so it was not suspected that the Rh protein would play such a role.

But among gases, carbon dioxide (CO2) and ammonia (NH3) are exceptional, the researchers explained. They both dissolve readily in water, which can slow their passage across oily membranes.

Recent evidence indicates that ammonium/methylammonium transporter (Amt) proteins act as gas channels for NH3. Unlike active transporters, channels allow multiple molecules of gas to move through at the same time, an important distinction for gases that need to move acr
'"/>

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley
6-Jun-2005


Page: 1 2 3 4

Related biology news :

1. NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
2. Saudi Arabias KAUST names WHOI first research partner
3. Multinational research: protecting ecology means understanding people, too
4. Newly created cancer stem cells could aid breast cancer research
5. Carnegie Mellons Peter Adams receives EPA research grant
6. Almac Diagnostics announces pioneering genetic research on ductal carcinoma in situ
7. Innovative tagging technique may help researchers better protect fish stocks
8. Penn researchers discover how key protein stops inflammation
9. UCF research links proteins, stem cells and potential Alzheimers treatment
10. ASU researchers partner with UOP to make biofuel for military jets a reality
11. Einstein researchers prototype vaccine could provide improved protection against tuberculosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/15/2016)... Md. , Nov. 15, 2016  Synthetic ... company developing therapeutics focused on the gut microbiome, ... offering of 25,000,000 shares of its common stock ... common stock at a price to the public ... proceeds to Synthetic Biologics from the offering, excluding ...
(Date:11/14/2016)... Technology, Inc. ("xG" or the "Company") (Nasdaq: XGTI, XGTIW), ... in challenging operating environments, announced its results for the ... a conference call to discuss these results on November ... Key Recent Accomplishments ... acquire Vislink Communication Systems. The purchase is expected to ...
(Date:6/27/2016)... Research and Markets has announced the addition ... to their offering. The report ... to grow at a CAGR of 12.28% during the period 2016-2020. ... in-depth market analysis with inputs from industry experts. The report covers ... The report also includes a discussion of the key vendors operating ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... Raleigh, NC (PRWEB) , ... December 01, 2016 ... ... the US Computational Science Symposium (CSS) and the popularity of US Single Day ... will take place in early Summer 2018, in Raleigh, NC. Topics of the ...
(Date:12/2/2016)... MA (PRWEB) , ... December 02, 2016 , ... Robots ... Light Event on December 3rd, 2016. The event, which is held on the ... work with helping Americans with Disabilities back into the workplace. Suitable Technologies is partnering ...
(Date:11/30/2016)... CLEVELAND , Nov. 30, 2016  GenomOncology today announced ... Vice President of Medical Affairs.  Dr. Coleman ... enhancing the company,s proprietary knowledge-enabled platform. The GenomOncology software suite ... of genetic sequencing data and clinical decision support, from quality ... , ...
(Date:11/30/2016)... 30, 2016 /PRNewswire/ -  Equicare Health Inc ., the ... recognized as one of the top 100 companies in ... listing that distinguishes the top digital health companies across ... step forward this year continually upgrading our product with ... base and team," says Len Grenier , CEO ...
Breaking Biology Technology:
Cached News: