HOME >> BIOLOGY >> NEWS
New stem-cell findings can help the body to cure itself

Researchers at Karolinska Institutet have identified an important mechanism that regulates how many new cells are produced by each intestinal stem cell. The study is published in the latest issue of the prestigious scientific journal, Cell. "This might eventually help us develop new drugs for things like neurological disorders and anaemia," says Professor Jonas Frisn.

In most organs of the body, old cells are continually being replaced by new. If too many new cells are produced, however, it can lead to overgrowth and tumour formation. Too few cells, on the other hand, can result in organ degeneration. It is therefore crucial that exactly the right number of cells are produced.

As many serious disorders cause a reduction in the production of new cells, scientists are keen to develop drugs that stimulate the process, which in turn could help the body to cure itself.

It has long been known that the new cells are often formed by immature cells known as stem cells, but the mechanism regulating the number of new cells produced has remained something of a mystery. However, in a new study to be published by Cell stem-cell researcher Jonas Frisn has succeeded in showing how the body's own stem cells do just this. Working alongside an American group of researchers, Professor Frisn and his team have identified a signal transduction process that regulates the degree of stem-cell division.

"Understanding how cell production is regulated increases our chances of producing drugs able to stimulate the endogenous production of new cells," says Professor Frisn.

He hopes that the new findings can be used to develop drugs that stimulate, for example, the formation of new nerve cells to treat conditions such as stroke and Parkinson's and skin cells to facilitate the healing of wounds. Professor Frisn is best known for his research on cerebral stem cells; the present study, however, has been carried out on stem cells in the intestine, one of the or
'"/>

Contact: Press Officer Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
16-Jun-2006


Page: 1 2

Related biology news :

1. Researchers find stem-cell therapy effective in targeting metastatic cancer
2. Committee review of stem-cell fraud finds editors followed all rules
3. Researchers discover key to human embryonic stem-cell potential
4. Researchers discover a stem-cell switch lurking within leukemias
5. New findings challenge established views on human genome
6. New findings challenge established views about human genome
7. Depiction of findings selected as 2007 Image of the Year by Society for Nuclear Medicine
8. New findings in smell and taste
9. Study produces conflicting findings on the use of anti-anemia drug in cancer patients
10. CMU researcher publishes anole lizard findings
11. Surprising airbag hazards among research findings at hearing safety conference

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/21/2017)... PORTLAND, Ore. , Feb. 22, 2017  IBM ... Companies (Avamere Health Services, Infinity Rehab, Signature Hospice, Home ... that will apply the power of IBM cognitive computing ... health centers. By analyzing data streaming from sensors in ... physical and environmental conditions, and obtain deeper learnings into ...
(Date:2/13/2017)... 2017  RSA Conference -- RSA, a Dell Technologies ... to enhance fraud detection and investigation across digital ... Fraud & Risk Intelligence Suite. The new platform ... insights from internal and external sources as well ... customers from targeted cybercrime attacks. "Fraudsters ...
(Date:2/8/2017)... YORK , Feb. 8, 2017 About ... individual,s voice to match it against a stored ... such as pitch, cadence, and tone are compared ... require minimal hardware installation, as most PCs already ... for different transactions. Voice recognition biometrics are most ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... and ROCKVILLE, Md. , March ... of Maxwell Biotech Venture Fund (MBVF), today announced positive ... added to the standard drug therapy regimen in patients ... small molecule drug discovered by scientists at Sequella, Inc. ... Institutes of Health. A total of ...
(Date:3/24/2017)... VILLAGE, Calif. , March 24, 2017   ... dermatology and aesthetics company, today announced that Richard ... Officer, effective March 24.   Peterson, who brings ... succeed John Smither , who is retiring at ... Sienna in an advisory capacity. Peterson joins Sienna from ...
(Date:3/23/2017)... 2017 Research and Markets has announced ... report to their offering. ... The Global Market for Bioproducts Should ... at a CAGR of 8.9%, This research ... into seven major product segments: bio-derived chemicals, biofuels, pharmaceuticals (biodrugs ...
(Date:3/23/2017)... Calif., March 23, 2017  BioPharmX Corporation (NYSE ... for the dermatology market, today reported financial results ... 2017, and will provide an update on the ... year. "We are pleased to report ... for BioPharmX," said President Anja Krammer. "We achieved ...
Breaking Biology Technology:
Cached News: