HOME >> BIOLOGY >> NEWS
New study aims to uncover genetic factors for hearing loss

PHOENIX, AZ AUGUST 29, 2006 Researchers at the Translational Genomics Research Institute (TGen), the House Ear Institute (HEI) and other organizations have initiated a study to identify the genes and genetic interactions involved in age-related hearing loss (presbycusis). The study, which was funded primarily by The Seaver Foundation, will use the latest state-of-the-art gene chip technology to uncover the genetic predisposition of presbycusis, a disorder thought to be caused by multiple genes, the environment and ethnicity. Affymetrix, a company specializing in tools for scientific research, is providing the micro-array technology necessary for processing the DNA samples in this study. Through an understanding of its molecular mechanisms, scientists hope to develop earlier diagnostics and ultimately prevent the disorder.

Presbycusis is the loss of hearing that gradually occurs in most individuals as they age. About 30-35 percent of adults between the ages of 65 and 75 years have a hearing loss. It is estimated that 40-50 percent of people 75 years and older have a hearing loss, according to the National Institutes of Health, and it often leads to isolation and depression. "This study will serve as a foundation for gene discoveries in other complex diseases and provides the groundwork for early diagnosis and treatment of age-related hearing loss," said Rick A. Friedman, M.D., Ph.D., the principal investigator of the study at House Ear Institute.

Researchers at TGen, working with their counterparts at the House Ear Institute, will utilize the Affymetrix technology to examine DNA markers 500,000 single-nucleotide polymorphisms (SNP) in high throughput fashion, which will provide them with the opportunity to define the genetic basis of this prevalent disorder. The study will evaluate nearly 2,000 patient samples collected at the Hereditary Deafness Laboratory at the University of Antwerp, Belgium. One of the short-term goals of the study is to crea
'"/>

Contact: Amy Erickson
aerickson@tgen.org
602-343-8522
The Translational Genomics Research Institute
29-Aug-2006


Page: 1 2

Related biology news :

1. New study warns limited carbon market puts 20 percent of tropical forest at risk
2. Clones on task serve greater good, evolutionary study shows
3. Pollution causes 40 percent of deaths worldwide, study finds
4. A study by the MUHC and McGill University opens a new door to understanding cancer
5. New study suggests Concord grape juice may provide protection against breast cancer
6. Preclinical study links gene to brain aneurysm formation
7. In limiting life span, study finds booming bacteria innocent
8. Multicenter study nets new lung tumor-suppressor gene
9. MIT study: Maturity brings richer memories
10. Chickadee, nutchatch presence in conifers increases tree growth, says CU-Boulder study
11. Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:4/4/2017)... , April 4, 2017   EyeLock LLC , ... that the United States Patent and Trademark Office (USPTO) ... covers the linking of an iris image with a ... and represents the company,s 45 th issued patent. ... is very timely given the multi-modal biometric capabilities that ...
(Date:3/30/2017)... KONG , March 30, 2017 The ... a system for three-dimensional (3D) fingerprint identification by adopting ground breaking ... into a new realm of speed and accuracy for use in ... at an affordable cost. ... ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, a global contract research, ... improve patient outcomes and quality of life, will now be offering its impurity ... to new regulatory requirements for all new drug products, including the finalization of ...
(Date:10/11/2017)... ... October 11, 2017 , ... At its national board meeting ... I. Sheikh, the co-founder, CEO and chief research scientist of Minnesota-based Advanced Space ... membership in ARCS Alumni Hall of Fame . ASTER Labs is a ...
(Date:10/11/2017)... ... ... eye wash is a basic first aid supply for any work environment, but most personal ... rinse first if a dangerous substance enters both eyes? It’s one less decision, and likely ... dual eye piece. , “Whether its dirt and debris, or an acid or alkali, getting ...
(Date:10/11/2017)... BALTIMORE, Md. (PRWEB) , ... October 11, 2017 ... ... for digital pathology, announced today it will be hosting a Webinar titled, “Pathology ... of  Advanced Pathology Associates , on digital pathology adoption best practices and how ...
Breaking Biology Technology:
Cached News: