New tuberculosis antibiotic may shorten treatment time, fight drug-resistant strains

This release is also available in French.

A new antibiotic shows promise, thus far in mice, for treating tuberculosis much faster than current drugs do, scientists report. Additional evidence indicates that the antibiotic may work against multidrug-resistant strains of the tuberculosis bug. Studies in healthy human volunteers have indicated that the drug is safe for humans to take, and further human studies are currently underway.

These findings, by Koen Andries of Johnson & Johnson Pharmaceutical Research and Development, LLC in Beerse, Belgium and colleagues, will appear online in the 9 December Science Express, part of the journal Science, published by AAAS, the nonprofit science society.

Globally, tuberculosis is second only to AIDS as a leading cause of death from infectious disease, causing approximately two million deaths per year. The tuberculosis and HIV epidemics fuel one another; at least 11 million adults are infected with both pathogens, according to the Global Alliance for TB Drug Development.

No new tuberculosis-specific drugs have been discovered in the last 40 years, and emerging strains of the bacterium that are resistant to multiple drugs are an increasingly worrisome problem. The current treatment for drug-sensitive tuberculosis recommended by the World Health Organization consists of a cocktail of drugs that must be taken for six to nine months.

"The world desperately needs a new tuberculosis drug that can combat resistant strains of the bacterium and that is easier for patients to take. The evidence thus far suggests that this new drug lead may be up to both tasks, which is encouraging news for global health," said Katrina Kelner, Deputy Editor, life sciences, at Science.

"If this drug is ultimately approved for humans, it could lead to a change in treatment paradigm for tuberculosis," Andries said.

The dr

Contact: Jessica Lawrence-Hurt
American Association for the Advancement of Science

Page: 1 2 3 4

Related biology news :

1. Einstein researchers prototype vaccine could provide improved protection against tuberculosis
2. Handicapping tuberculosis may be the way to a better vaccine
3. Developing a more effective vaccine for tuberculosis
4. Why is long-term therapy required to cure tuberculosis?
5. UA researchers identify new adherence factor, Pili, produced by tuberculosis
6. Shorter tuberculosis therapies could lead to substantial reductions in cases and deaths
7. Pitt phage hunter takes on tuberculosis
8. Cost-effectiveness of treating multidrug-resistant tuberculosis
9. New potential drug target in tuberculosis
10. National Institutes of Health funds $13.7 million for Texas tuberculosis study
11. Einstein researchers find potential new drugs for tuberculosis

Post Your Comments:

(Date:5/16/2017)... , May 16, 2017   Bridge ... health organizations, and MD EMR Systems , ... development partner for GE, have established a partnership ... Portal product and the GE Centricity™ products, including ... EMR. These new integrations will ...
(Date:4/19/2017)... The global military biometrics market ... by the presence of several large global players. The ... major players - 3M Cogent, NEC Corporation, M2SYS Technology, ... 61% of the global military biometric market in 2016. ... military biometrics market boast global presence, which has catapulted ...
(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia ... be hosting a Webinar titled, “Pathology is going digital. Is your lab ready?” ... pathology adoption best practices and how Proscia improves lab economics and realizes an ...
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/11/2017)... ... October 11, 2017 , ... A new study published in ... and fresh in vitro fertilization (IVF) transfer cycles. The multi-center matched ... , After comparing the results from the fresh and frozen transfer cohorts, the ...
(Date:10/10/2017)... CALIF. (PRWEB) , ... October 10, 2017 , ... San ... part of its corporate rebranding initiative announced today. The bold new look is ... reach, as the company moves into a significant growth period. , It will also ...
Breaking Biology Technology:
Cached News: