HOME >> BIOLOGY >> NEWS
New tumor markers -- 'Spot the differences'

This release is available in Spanish.

The term cancer (from the Greek karkinos, which means sea crab) was used for the first time by Greek doctor Hippocrates five hundred years b.C. to define the tumours that he observed in his patients. Nowadays it is still difficult to diagnose, and prognosis is bad. Cancer is already the main cause of death in many countries, ranking even above cardiovascular diseases.

Pancreatic cancer (PC), the subject of this thesis, has the poorest prognosis of all cancers: the survival rate after five years with the disease is less than 5% and on average, patients who have been diagnosed with it do not live longer than six months.

The modus operandi of cells is well known: the genes (DNA) are the masterminds of the system and their role is to give orders. Those orders are transmitted in the form of messages (RNA), which ultimately become molecules that do the work (proteins). Since all cells have similar genes, they are all able to give the same range of orders. However, depending on their role and the signs and information they receive from their surroundings, each cell type sends only specific messages at any one time. While in normal cells this process is carried out following an organized pattern, this pattern of messages changes completely in cancer cells. When pancreatic cells transform into cancer cells, they abandon their usual functions and start sending abnormal messages, which encourage them to quickly divide and invade nearby tissues.

The aim of this PhD was to intercept messages sent by cancerous pancreatic cells and compare them with those sent by healthy pancreatic cells. This comparison would indicate which orders (messages) are the ones that make the cancer grow and invade and which weapons (proteins) it uses to do so. In order to carry out this work we used microarrays or DNA-chips
'"/>

Contact: Garazi Andonegi
garazi@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
20-Jun-2007


Page: 1 2

Related biology news :

1. Invasion of the brain tumors
2. Multicenter study nets new lung tumor-suppressor gene
3. Defects in critical gene lead to accelerated lung tumor growth
4. A friendly foe -- Bacteria residing in the gut boost immune response to tumors
5. MIT IDs link between brain tumor proteins
6. Researchers identify genetic mutation that may alter tumor cell proliferation
7. Nanoparticles carry chemotherapy drug deeper into solid tumors
8. Frog molecule could provide drug treatment for brain tumors
9. Mathematics reveals genetic pattern of tumor growth
10. CSHL scientists successfully target tumor microenvironment to stop cancer growth
11. Study could impact noninvasive treatment of cancer tumors

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: New tumor markers Spot the differences

(Date:8/20/2014)... Women who are poor experience higher cortisol levels ... levels of the stress hormone, putting them at ... to a new research from the University of Colorado ... American Journal of Human Biology , is the ... directly to the socioeconomic status of their mothers during ...
(Date:8/20/2014)... 4,000 members, it triggers an important first stage in ... of comb used for rearing male reproductive, called drones. ... and Behaviour at Cornell University, led by Michael Smith, ... The results are published in Springer,s journal Naturwissenschaften ... isn,t always a honeybee colony,s top priority. Early ...
(Date:8/20/2014)... leaves, photosystem 1 (PS1) absorbs light and its ... carbon dioxide to biomass. Photovoltaic devices, mostly build ... but produce electricity. One approach for the development ... the semi-conductor with the isolated membrane protein complexes ... a highly stable PS1 from thermophilic cyanobacteria that ...
Breaking Biology News(10 mins):CU Denver researcher shows economic disparities impact infant health 2Worker bees 'know' when to invest in their reproductive future 2A semi-artificial leaf faster than 'natural' photosynthesis 2
(Date:8/21/2014)... 2014 SoundConnect , a ... as one of the nation’s Fastest Growing Private ... the 2nd consecutive year. Inc. magazine today ranked ... 500|5000, an exclusive ranking of the nation's fastest-growing ... look at the most important segment of the ...
(Date:8/20/2014)... time, chemists have succeeded in measuring vibrational motion of ... study reveals how vibration of a single molecule differs ... The study was performed at the University of California, ... of Jyvskyl works as a visiting fellow under professor ... The second team was lead by Professor Eric O. ...
(Date:8/20/2014)... Francisco, CA (PRWEB) August 20, 2014 ... Conference is being held on October 29-30 in ... perspectives from industry, academic and government researchers and clinicians ... in the space. , In the twelve years ... one hundred therapies have been introduced with pharmacogenetic information ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 ... released today including improvements to the enterprise replication ... connectors for Lucene, SOLR and Elasticsearch. This release ... this high performance triplestore – GraphDB™ was formerly ... in deploying the only mature enterprise resilient RDF ...
Breaking Biology Technology:SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Seeing a molecule breathe 26th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4
Cached News: