HOME >> BIOLOGY >> NEWS
New tumor markers -- 'Spot the differences'

This release is available in Spanish.

The term cancer (from the Greek karkinos, which means sea crab) was used for the first time by Greek doctor Hippocrates five hundred years b.C. to define the tumours that he observed in his patients. Nowadays it is still difficult to diagnose, and prognosis is bad. Cancer is already the main cause of death in many countries, ranking even above cardiovascular diseases.

Pancreatic cancer (PC), the subject of this thesis, has the poorest prognosis of all cancers: the survival rate after five years with the disease is less than 5% and on average, patients who have been diagnosed with it do not live longer than six months.

The modus operandi of cells is well known: the genes (DNA) are the masterminds of the system and their role is to give orders. Those orders are transmitted in the form of messages (RNA), which ultimately become molecules that do the work (proteins). Since all cells have similar genes, they are all able to give the same range of orders. However, depending on their role and the signs and information they receive from their surroundings, each cell type sends only specific messages at any one time. While in normal cells this process is carried out following an organized pattern, this pattern of messages changes completely in cancer cells. When pancreatic cells transform into cancer cells, they abandon their usual functions and start sending abnormal messages, which encourage them to quickly divide and invade nearby tissues.

The aim of this PhD was to intercept messages sent by cancerous pancreatic cells and compare them with those sent by healthy pancreatic cells. This comparison would indicate which orders (messages) are the ones that make the cancer grow and invade and which weapons (proteins) it uses to do so. In order to carry out this work we used microarrays or DNA-chips
'"/>

Contact: Garazi Andonegi
garazi@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
20-Jun-2007


Page: 1 2

Related biology news :

1. Invasion of the brain tumors
2. Multicenter study nets new lung tumor-suppressor gene
3. Defects in critical gene lead to accelerated lung tumor growth
4. A friendly foe -- Bacteria residing in the gut boost immune response to tumors
5. MIT IDs link between brain tumor proteins
6. Researchers identify genetic mutation that may alter tumor cell proliferation
7. Nanoparticles carry chemotherapy drug deeper into solid tumors
8. Frog molecule could provide drug treatment for brain tumors
9. Mathematics reveals genetic pattern of tumor growth
10. CSHL scientists successfully target tumor microenvironment to stop cancer growth
11. Study could impact noninvasive treatment of cancer tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/23/2016)... March 23, 2016 ... Sicherheit Gesichts- und Stimmerkennung mit Passwörtern ... (NASDAQ: MESG ), ein führender Anbieter ... Unternehmen mit SpeechPro zusammenarbeitet, um erstmals dessen ... wird die Möglichkeit angeboten, im Rahmen mobiler ...
(Date:3/22/2016)... OTTAWA, Ontario , PROVO ... 2016 Newborn Screening Ontario (NSO), which operates ... for molecular testing, and Tute Genomics and ... process management technology respectively, today announced the launch of ... new next-generation sequencing (NGS) testing panel. ...
(Date:3/18/2016)... 2016 --> --> ... Manned & Unmanned Vehicles, Physical infrastructure and Perimeter Surveillance & ... the border security market and the continuing migration crisis in ... Europe has led visiongain to publish this unique ... --> defence & security companies in the border ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... UAS LifeSciences, ... launch of their brand, UP4™ Probiotics, into Target stores nationwide. The company, which ... to add Target to its list of well-respected retailers. This list includes such ...
(Date:6/23/2016)... Houston Methodist Willowbrook Hospital has signed ... to serve as their official health care provider. ... will provide sponsorship support, athletic training services, and ... volunteers, athletes and families. "We are ... and to bring Houston Methodist quality services and ...
(Date:6/23/2016)... --  EpiBiome , a precision microbiome engineering company, today ... from Silicon Valley Bank (SVB). The financing will allow ... drug development efforts, as well as purchase additional lab ... been an incredible strategic partner to us – one ... provide," said Dr. Aeron Tynes Hammack , EpiBiome,s ...
(Date:6/23/2016)... June 23, 2016 Apellis Pharmaceuticals, Inc. ... clinical trials of its complement C3 inhibitor, APL-2. ... multiple ascending dose studies designed to assess the ... subcutaneous injection in healthy adult volunteers. ... as a single dose (ranging from 45 to ...
Breaking Biology Technology:
Cached News: