News tips from the Journal of Biological Chemistry

Articles to be published in the May 4, 2007 issue of the Journal of Biological Chemistry (Vol. 282, No. 18)


  • Cholesterol Metabolism Without Oxygen
  • Compound Effective against Blood Cancer Reveals Its Secrets
  • Fighting Bacteria by Preventing Them from Talking to Each Other
  • New Insight into HIV Infection

Cholesterol Metabolism Without Oxygen

This article was featured as a Paper of the Week by the Journal of Biological Chemistrys Editors, meaning that it belongs to the top one percent of papers reviewed in significance and overall importance.

Researchers report the first details of how cholesterol is metabolized without oxygen.

Cholesterol, a precursor to steroid hormones and a constituent of cell membranes, is usually broken down inside an organism in the presence of oxygen. The chemical reactions involved are well-known and have been used in industry to manufacture synthetic sexual hormones and dietary supplements. Cholesterol can also be broken down without oxygen, but very little is known about the chemical mechanisms at work.

Georg Fuchs and colleagues report the first study of these mechanisms. They used a bacterium called Sterolibacterium denitrificans and carefully looked at how cholesterol was broken down in this organism. The results, which revealed new compounds not previously seen in reactions involving oxygen, could be used to produce new pharmaceuticals for cholesterol-related diseases.

Article: Initial steps in the anoxic metabolism of cholesterol by the denitrifying Sterolibacterium denitrificans by Yin-Ru Chiang, Wael Ismail, Michael Muller, and Georg Fuchs

MEDIA CONTACT: Georg Fuchs, Mikrobiologie, Fakultat fur Biologie, Universitat Freiburg, Germany; tel: +49-7612032649; e-mail:

Contact: Pat Pages
American Society for Biochemistry and Molecular Biology

Page: 1 2 3 4

Related biology news :

1. News tips from the Journal of Neuroscience
2. News tips from the Journal of Neuroscience
3. News tips from the Journal of Neuroscience
4. News tips from the Journal of Neuroscience
5. Tips from the Journals of the American Society for Microbiology
6. Journalists can register now for ECCO 14 -- the European Cancer Conference
7. Journal of Alzheimers Disease achieves significant impact factor
8. News tips from the Journal of Neuroscience
9. Highlights from the July 2007 Journal of the American Dietetic Association
10. News tips from the Journal of Neuroscience
11. Journal of Nuclear Medicines impact grows, remains consistently high over past 5 years

Post Your Comments:

(Date:7/18/2020)... ... ... Commercial launch readiness is a critical stage in a product life cycle. While the ... economic downturn will only increase price pressures overall for the industry. The era of ... every product launch is critical. However, history shows that only a third of product ...
(Date:7/2/2020)... ... July 02, 2020 , ... ... a publication detailing the use of its revolutionary NEXTGENPCR endpoint thermocycler to ... in 16 minutes. The article, titled "Ultra-fast one-step RT-PCR protocol for the ...
(Date:6/25/2020)... (PRWEB) , ... June 24, 2020 , ... ... cloud-based enterprise software and software-driven clinical data services that accelerate drug development, is ... low-dose selinexor, an XPO1 inhibitor, in hospitalized patients with severe COVID-19. This is ...
Breaking Biology News(10 mins):
(Date:8/15/2020)... ... August 13, 2020 , ... Inc. magazine ... the most prestigious ranking of the nation’s fastest-growing private companies. The list represents ... dynamic segment—its independent small businesses. Intuit, Zappos, Under Armour, Microsoft, Patagonia, and many ...
(Date:8/3/2020)... ... August 03, 2020 , ... ERT, ... and CEO has been named one of the 100 most inspiring individuals in ... 100 honorees are selected based on how they have inspired their colleagues and ...
(Date:7/31/2020)... ... 2020 , ... Anomet Products has introduced new custom composite ... with CRM, neurostimulation, vascular, and related devices. , Anomet Medical Clad Wire ... and cost criteria; especially where solid wire is limited. Typical configurations for implantable ...
(Date:7/22/2020)... ... July 22, 2020 , ... Join experts from Reed Tech , ... Solutions, in a one hour live webinar on Thursday, August 13, 2020 ... for drugs and medical devices. Specifically, for medical devices, the NMPA has departments dealing ...
Breaking Biology Technology:
Cached News: