News tips from the Journal of Neuroscience

A fly pheromone receptor

Tal Soo Ha and Dean P. Smith

Insects use pheromone signaling for all sorts of interesting behaviors, yet only a single volatile pheromone has been identified in Drosophila, the lipid 11-cis-vaccenyl acetate (VA). Upon release by males, VA induces aggregation behavior in both sexes. This week, Ha and Smith identify VA's molecular target on trichoid sensilla, located on the ventrallateral surface of the antenna. VA activates olfactory neurons on T1-type sensilla. The authors screened the Drosophila odorant receptor (Or) gene family in flies lacking functional T1 sensilla. One gene, Or67d was reduced or absent in the mutants. Misexpression of Or67d in olfactory neurons of non-T1 sensilla conferred sensitivity to VA. LUSH, an extracellular protein expressed by sensillar lymph cells, is required for T1 sensitivity to VA and is also expressed in non-T1 sensilla. The lush1 mutation eradicated VA sensitivity in transgenic flies misexpressing Or67d. Thus, VA sensitivity requires both Or67d and LUSH.

Visualizing a netrin gradient

Timothy E. Kennedy, Hao Wang, Wallace Marshall, and Marc Tessier-Lavigne

Chemotropic guidance cues can act through gradients formed by graded expression levels or graded distribution. This week, Kennedy et al. visualized the netrin-1 gradient that guides commissural axons within the developing spinal cord. The authors generated antibodies to visualize netrin-1 and netrin-2 in the developing chick spinal cord. At the time when commissural axons began to extend, netrin-1 immunoreactivity was found not only in the floor plate where it is expressed by floor plate cells, but also in the ventral neural epithelium and dorsal spinal cord. Netrin-2 in contrast had a much more restricted pattern limited to neural epithelial cells that express it in the ventral spinal cord, and it was expressed at much lower lev

Contact: Sara Harris
Society for Neuroscience

Page: 1 2 3

Related biology news :

1. News tips from the Journal of Neuroscience
2. News tips from the Journal of Neuroscience
3. News tips from the Journal of Neuroscience
4. News tips from the Journal of Neuroscience
5. Tips from the Journals of the American Society for Microbiology
6. Journalists can register now for ECCO 14 -- the European Cancer Conference
7. Journal of Alzheimers Disease achieves significant impact factor
8. News tips from the Journal of Neuroscience
9. Highlights from the July 2007 Journal of the American Dietetic Association
10. News tips from the Journal of Neuroscience
11. Journal of Nuclear Medicines impact grows, remains consistently high over past 5 years

Post Your Comments:

(Date:8/26/2020)... ... August 24, 2020 , ... Elgia Therapeutics , ... fibrotic diseases, today announced that Dr. Stacie Canan has joined the company as ... previously served as Executive Director of Global Health at Bristol Myers Squibb (formerly ...
(Date:8/21/2020)... Mass. (PRWEB) , ... August 18, 2020 , ... ... approaches to cell therapy, today announced that the U.S. Food and Drug Administration ... of Sentien’s lead asset, SBI-101, for the treatment of severe COVID-19. Approval of ...
(Date:8/12/2020)... ... August 12, 2020 , ... Mosio recently announced its ... public health agencies of all sizes. With a focus on tracking symptoms and ... appropriate health care, Mosio helps public health departments automate communications and provide more ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... ... July 08, 2020 , ... Bode Technology, a ... laboratory operations through its COVID-19 testing service, Bode-CARES . Bode-CARES combines high-volume ... Bode-CARES provides a turnkey solution that includes a comprehensive collection and virus-management ...
(Date:7/7/2020)... ... 2020 , ... R3 International is now offering stem cell therapy for Alzheimers ... Depending on the patient's condition, treatment may be offered IV, intrathecal or with a ... of Alzheimers dementia, and the incidence continues to increase as individuals live longer. There ...
(Date:7/1/2020)... (PRWEB) , ... June 30, ... ... expert tissue data insights, today announced that the launch of a new ... along with data about the tumor microenvironment (TME). , “Flagship’s TissueInsight is ...
(Date:6/28/2020)... ... June 26, 2020 , ... The Security Industry ... its strong opposition to the recently introduced bicameral Facial Recognition and Biometric ... most federal use of nearly all biometric and related image analytics technologies, incorrectly ...
Breaking Biology Technology:
Cached News: