News tips from the Journal of Neuroscience

1. Putting the Freeze on the Presynaptic Terminal
La Siksou, Philippe Rostaing, Jean-Pierre Lechaire, Thomas Boudier, Toshihisa Ohtsuka, Anna Fejtov, Hung-Teh Kao, Paul Greengard, Eckart D. Gundelfinger, Antoine Triller, and Serge Marty

This week, Siksou et al. give us some close-up views of the cytomatrix in presynaptic terminals. To catch synaptic vesicles and particularly their filamentous network in the act, the authors immobilized rodent CA1 hippocampal slices by high-pressure freezing. Cryosubstitution and embedding preserved the architecture of the protein network. Electron tomography images were then reconstructed for a three-dimensional view. Within presynaptic boutons, filaments connected synaptic vesicles (SVs) to one another, and longer filaments (3060 nm) linked the network to active zones in the presynaptic plasma membrane. On average, each SV was connected to 1.5 other SVs. Synapsins have been considered to be the filaments that maintain SV in position at the active zone. However, in mice lacking three synapsins, SV position was unchanged, and filaments linking them together were still present despite a significant drop in SV number. Thus, the cytomatrix appears not to depend on the integrity of synapsins.

2. Early Glucocorticoids and Later Neuroprotection
Paola Casolini, Maria Rosaria Domenici, Carlo Cinque, Giovanni Sebastiano Alem, Valentina Chiodi, Mariangela Galluzzo, Marco Musumeci, Jerome Mairesse, Anna Rita Zuena, atrizia Matteucci, Giuseppe Marano, tefania Maccari, Ferdinando Nicoletti, and Assia Catalani

This week, Casolini et al. show that maternal behavior during a pups neonatal life makes a long-lasting imprint on the hypothalamic-pituitary-adrenal (HPA) axis. Rat dams received water supplemented with corticosterone (CORT), a hormonal treatment intended to mimic mild stress. The dams displayed increased maternal care behaviors with their nursing pups during the first 3 weeks of life. Rema

Contact: Sara Harris
Society for Neuroscience

Page: 1 2 3

Related biology news :

1. News tips from the Journal of Neuroscience
2. News tips from the Journal of Neuroscience
3. News tips from the Journal of Neuroscience
4. News tips from the Journal of Neuroscience
5. Tips from the Journals of the American Society for Microbiology
6. Journalists can register now for ECCO 14 -- the European Cancer Conference
7. Journal of Alzheimers Disease achieves significant impact factor
8. News tips from the Journal of Neuroscience
9. Highlights from the July 2007 Journal of the American Dietetic Association
10. News tips from the Journal of Neuroscience
11. Journal of Nuclear Medicines impact grows, remains consistently high over past 5 years

Post Your Comments:

(Date:7/2/2020)... REDWOOD CITY, Calif. (PRWEB) , ... July 01, ... ... stage biotech company, presented its phase 1a findings of Neihulizumab, a biologic for ... annual conference in June 2020. Led by hemato-oncologist Dr. Paul J Martin of ...
(Date:6/28/2020)... Fla. (PRWEB) , ... June 25, 2020 , ... In ... focus on innovations in accelerated Point of Care Testing solutions (POCT). Check local listings ... Samples are collected at medical offices and are shipped to labs throughout the country. ...
(Date:6/23/2020)... ... June 23, 2020 , ... ... pleased to announce the next event in a series of TOPIQ webinars, which ... TOPIQ series of webinars was developed in response to social distancing measures that ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... Ariz. (PRWEB) , ... July 29, 2020 , ... R3 ... joint injections for only $3950. With 50 million stem cells total, patients may choose ... stem cell therapy works for arthritic joints (BMC Musculoskelet Disord. 2016). At R3 International, ...
(Date:7/31/2020)... ... July 29, 2020 , ... Editas Medicine, Inc. ... of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and ... a strategic partnership whereby Catalent will provide support for the development, manufacturing, and ...
(Date:7/22/2020)... ... , ... Join experts from Reed Tech , Gary Saner, Sr. Manager, ... hour live webinar on Thursday, August 13, 2020 at 11am EDT (4pm ... devices. Specifically, for medical devices, the NMPA has departments dealing with medical device registration ...
(Date:7/18/2020)... ... July 17, 2020 , ... dicentra , ... sciences and food industries, is pleased to announce that Charles Galea has joined ... Development. , Charles is an accomplished and results-driven sales executive with over 10 ...
Breaking Biology Technology:
Cached News: