HOME >> BIOLOGY >> NEWS
No evidence that widely prescribed statins protect against prostate cancer

PHILADELPHIA − A large community-based study refutes previous findings that statins a top-selling drug class, worldwide -- might cut ones risk of developing prostate cancer by reducing production of the male hormones that fuel cancer growth.

Researchers from the New England Research Institutes found that while men using statins did indeed have lower blood levels of androgens such as testosterone, it was more likely attributable to poor health rather than the use of statins. Their findings are published in the August issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

The public health significance is that our study provides evidence that statins may not have a clinically meaningful impact on testosterone in the blood, although further studies should be done, said study author, Susan A. Hall, Ph.D., a research scientist at the New England Research Institutes. That doesnt mean that statins may be lowering prostate cancer risk through one or more alternative pathways, but it doesnt appear to be working through reduction of male hormones,

Statins lower cholesterol and are commonly prescribed to treat and prevent heart disease. Since cholesterol is required for the production of male hormones researchers have theorized that statins may reduce production of these hormones. A large, recent study found that men using statin drugs were at lowered risk of developing metastatic or fatal prostate cancer, especially if the drugs were used over a long period of time. But other studies on statin use and prostate cancer risk have had mixed results, according to Hall.

To study a narrow question − whether statin use reduces androgen concentrations in the blood − the researchers examined data from the Boston Area Community Health (BACH) survey, a population-based, NIH-sponsored, epidemiologic study. Data were collected between 2002 and 2005 on thousands of
'"/>

Contact: Greg Lester
lester@aacr.org
267-646-0554
American Association for Cancer Research
9-Aug-2007


Page: 1 2

Related biology news :

1. Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
2. CU researchers discover evidence of very recent human adaptation
3. Research finds evidence tropical cyclones have climate-control role
4. New evidence of human culture among primates
5. Study advances evidence for receptors role in alcohol pleasure and problems
6. Study provides first genetic evidence of long-lived African presence within Britain
7. More human-Neandertal mixing evidence uncovered
8. First evidence to show elephants, like humans, apes and dolphins, recognize themselves in mirror
9. New MUHC study adds more evidence to clear measles mumps rubella vaccine as a risk factor for autism
10. Possible evidence of cell division, differentiation found in oldest known embryo fossils
11. Compelling evidence demonstrates that Hobbit fossil does not represent a new species of hominid

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/25/2019)... ... September 25, 2019 , ... The esteemed dental implant specialists ... implants for a variety of procedures, including single tooth replacement, new “teeth-in-a-day” immediately ... Dental implants offer patients permanent tooth replacement solutions that look and function ...
(Date:9/24/2019)... ... 2019 , ... HT Medical today announced a ... with the expansion of its proprietary Ti3D® spinal interbody cages. Through this launch, ... cervical and lumbar instrumentation sets available for surgical use. , The additional Ti3D ...
(Date:9/17/2019)... SALT LAKE CITY (PRWEB) , ... September 17, ... ... Group SA, and a group of doctors, scientists and engineers from the Medical ... to present the results of their work to-date in creating a neuroprosthetic system ...
Breaking Biology News(10 mins):
(Date:10/8/2019)... ... 2019 , ... Erchonia Corporation, the global leader in the ... the U.S. Food and Drug Administration (FDA) has granted the company 510(k) market ... chronic neck and shoulder pain of musculoskeletal origin. , Erchonia continues to be ...
(Date:10/3/2019)... ... October 01, 2019 , ... Cheyenne is a beautiful and strong Quarter ... owns and operates Rebel’s Run , which offers riding lessons and trail riding ... trail riding guests. Mimi describes her as her “go to horse.” Thus, ...
(Date:10/3/2019)... ... October 02, 2019 , ... eKare’s inSight® digital 3D imaging and ... run by the East Midlands Academic Health Science Network (EMAHSN), the innovation arm of ... NHS by providing support to develop and deploy solutions to the most pressing challenges ...
(Date:9/30/2019)... , ... September 30, 2019 , ... ... science newsletter from Rigaku Corporation , is now available online on the ... X-ray based materials science, including X-ray diffraction, fluorescence and imaging, and presents articles, ...
Breaking Biology Technology:
Cached News: