HOME >> BIOLOGY >> NEWS
No evidence that widely prescribed statins protect against prostate cancer

PHILADELPHIA − A large community-based study refutes previous findings that statins a top-selling drug class, worldwide -- might cut ones risk of developing prostate cancer by reducing production of the male hormones that fuel cancer growth.

Researchers from the New England Research Institutes found that while men using statins did indeed have lower blood levels of androgens such as testosterone, it was more likely attributable to poor health rather than the use of statins. Their findings are published in the August issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

The public health significance is that our study provides evidence that statins may not have a clinically meaningful impact on testosterone in the blood, although further studies should be done, said study author, Susan A. Hall, Ph.D., a research scientist at the New England Research Institutes. That doesnt mean that statins may be lowering prostate cancer risk through one or more alternative pathways, but it doesnt appear to be working through reduction of male hormones,

Statins lower cholesterol and are commonly prescribed to treat and prevent heart disease. Since cholesterol is required for the production of male hormones researchers have theorized that statins may reduce production of these hormones. A large, recent study found that men using statin drugs were at lowered risk of developing metastatic or fatal prostate cancer, especially if the drugs were used over a long period of time. But other studies on statin use and prostate cancer risk have had mixed results, according to Hall.

To study a narrow question − whether statin use reduces androgen concentrations in the blood − the researchers examined data from the Boston Area Community Health (BACH) survey, a population-based, NIH-sponsored, epidemiologic study. Data were collected between 2002 and 2005 on thousands of
'"/>

Contact: Greg Lester
lester@aacr.org
267-646-0554
American Association for Cancer Research
9-Aug-2007


Page: 1 2

Related biology news :

1. Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
2. CU researchers discover evidence of very recent human adaptation
3. Research finds evidence tropical cyclones have climate-control role
4. New evidence of human culture among primates
5. Study advances evidence for receptors role in alcohol pleasure and problems
6. Study provides first genetic evidence of long-lived African presence within Britain
7. More human-Neandertal mixing evidence uncovered
8. First evidence to show elephants, like humans, apes and dolphins, recognize themselves in mirror
9. New MUHC study adds more evidence to clear measles mumps rubella vaccine as a risk factor for autism
10. Possible evidence of cell division, differentiation found in oldest known embryo fossils
11. Compelling evidence demonstrates that Hobbit fossil does not represent a new species of hominid

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2020)... (PRWEB) , ... June 22, 2020 , ... The field ... Typically, ligand binding assays (LBA) have dominated this area. However, the use of mass ... years. , This now necessitates the question “How do you choose which approach to ...
(Date:6/19/2020)... ... ... Join experts from Envigo Lauren Klaskala, Project Manager – Custom Transgenic Models ... July 8, 2020 at 11am EDT (4pm BST/UK). , Nuclease-based technologies such as CRISPR ... the genome may be more straightforward, the challenge to create an optimal model for ...
(Date:6/5/2020)... ... June 04, 2020 , ... “Although we are disappointed ... well-being of our attendees, staff, and the public. We remain committed to creating ... ways to collaborate virtually,” said Julie Sutcliffe, President of WMIS. , ...
Breaking Biology News(10 mins):
(Date:5/15/2020)... (PRWEB) , ... May 14, 2020 , ... ... to undergo multiple open heart surgeries before becoming adults. The reason: ... , To address this critical unmet need, the Department of Defense has awarded ...
(Date:5/15/2020)... ... , ... Sentien Biotechnologies, Inc., a clinical-stage biotechnology company developing novel approaches to ... Ganz will continue to lead Sentien’s Board of Directors, a role he has filled ... and Sentien’s management team. , Mr. Ganz has more than 30 years ...
(Date:5/14/2020)... ... May 12, 2020 , ... NanoString Technologies ... together thousands of industry leaders, clinicians, research scientists, medical professionals and academics from ... June, MD, Director of the Center for Cellular Immunotherapies at the Perelman School ...
(Date:5/14/2020)... ... May 13, 2020 , ... Early ... readouts, providing little or no information on the drug’s mechanism of action (MOA). ... of compounds by measuring the activity of molecular pathways. This information can complement ...
Breaking Biology Technology:
Cached News: