North Shore-LIJ receives FDA approval for new drug application to manufacture PET scan drug

ures used in the manufacture of the drug.

Fludeoxyglucose F 18 is the most widely used radiopharmaceutical in PET scanning. A radiopharmaceutical is a specially designed drug that consists of a molecular compound that is similar to one normally used by cells -- in this case, glucose -- but which is tagged with radioactive atoms. When the cell absorbs the radiopharmaceutical, gamma rays are released as the unstable radioactive atoms rearrange themselves into a stable configuration. Traveling at the speed of light, the gamma rays allow the PET camera to generate a picture of those cells and organs at work. The amount of radiation to which a person is exposed is minimal and compares to that of a basic X-ray or CT scan.

Radioactive fluorine atoms are produced by a cyclotron, like the state-of-the-art GE PETrace Cyclotron purchased by North Shore-LIJ last year and installed at its research institute at a total cost of $2.6 million. It is the only cyclotron on Long Island used to produce radiopharmaceuticals for both research and clinical PET scanning. Once the radioactive atoms are produced, a sophisticated radiochemistry instrument such as a Fludeoxyglucose synthesizer incorporates the radioactive atoms into a chemical compound such as deoxyglucose and produces the drug. Fludeoxyglucose F 18 is manufactured in a saline solution, stored in glass vials and injected intravenously just prior to the actual PET scanning procedure.

The speed of radioactive decay of Fludeoxyglucose F 18, or its half-life, is just under two hours. This means that every two hours, half of its radiation-emitting ability is lost. Therefore, the drug must be used the same day it is manufactured, often within just hours of production -- creating a challenge for transporting the drug over any distance. The drug strength produced depends on the capacity of the cyclotron. The greater the strength that can be made, the more drug is available for PET imaging studies and the farthe

Contact: Christina Verni
North Shore-Long Island Jewish (LIJ) Health System

Page: 1 2 3

Related biology news :

1. Changing climate will challenge Northeast agriculture, CU expert warns
2. Northern forests less effective than tropical forests in reducing global warming
3. Genomatix expands operations in North America
4. Overfishing great sharks wiped out North Carolina bay scallop fishery
5. Iowa State University botanists identify new species of North American bamboo
6. Climate changes, Cod collapse have altered North Atlantic ecosystems
7. Altered ocean currents disturb ecosystem off Northern California and Oregon coast
8. Hotspots of mercury contamination identified in eastern North America
9. UGA study identifies North American wild bird species that could transmit bird flu
10. National Academies advisory: Pollinators in North America
11. Northern bogs may have helped kick-start past global warming

Post Your Comments:

(Date:10/9/2015)... Oct. 09 2015 ... of the "Samsung Galaxy S6 Fingerprint ... to their offering. --> http://www.researchandmarkets.com/research/6g9l3b/samsung_galaxy_s6 ... "Samsung Galaxy S6 Fingerprint Sensor - ... offering. --> Research and Markets ...
(Date:10/8/2015)... , Oct. 8, 2015 Synaptics ... human interface solutions, announced today that it will ... fiscal 2016 on Thursday, October 22, 2015, after ... a corresponding conference call for analysts and investors ... which management may discuss forward-looking information.    ...
(Date:10/8/2015)... CITY , 8. Oktober 2015 /PRNewswire/ ... ein global tätiges Unternehmen des Bereiches Tracking, ... Vertrag mit der Gefängnisbehörde Virginias (Department of ... Rahmen elektronische Überwachungsdienste für alle Strafen geliefert ... Derek Cassell , Präsident für den Amerikanischen ...
Breaking Biology News(10 mins):
(Date:10/9/2015)... , Oct. 9, 2015 On October ... the Congressional Record her statement recognizing the third annual ... 11-17. IPAW is sponsored by the Plasma Protein ... is designed to:   , Raise global awareness ... plasma donors in saving and improving lives , ...
(Date:10/9/2015)... Governor Tom Wolf announced today ... on developing T-cell receptor cancer immunotherapy treatments, will create ... expansion project. Pennsylvania , and ... 110 new, high-paying jobs will be created with this ... proposal includes sustained funding for the life science sector ...
(Date:10/9/2015)... HERSHEY, Pa. and ROCKVILLE, ... Therapeutics, Inc. ("ITI"), a privately-held biotechnology company developing ... today announced that it has entered into an ... on LAMP-vax products for the treatment or prevention ... Upon execution of the agreement, Immunomic Therapeutics will ...
(Date:10/9/2015)... , Oct. 9, 2015  DePuy Synthes Trauma* announced ... with Q-PACK ®  Technology**, the only pre-hydrated demineralized ... extremity procedures (foot and ankle, hand and wrist), including ... made here at the 2015 Orthopaedic Trauma Association (OTA) ... natural scaffold for new bone growth) and osteoinductive 2,3 ...
Breaking Biology Technology:
Cached News: