OHSU study says stem cell 'fusion' occurs...( rating rapidly turning over damaged tis...)

OHSU study says stem cell 'fusion' occurs in tumors

rating rapidly turning over damaged tissue, or may even be implicated in disease progression.

"The intestinal lining is the protective barrier between your body and the outside environment. Therefore, it sees all of the offensive contaminants that you ingest, from the beer you drink to the charbroiled hamburger you eat, that can induce mutations in the cells. The gut protects itself by rapidly turning over its epithelial cells. Plus, when there is damage to the surface lining, it is critical that regeneration and reestablishment of the barrier occurs rapidly. We think that cell fusion with bone marrow cells is the body's way of jump-starting that regeneration of the epithelium," she said.

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Contact: Jonathan Modie
modiej@ohsu.edu
503-494-8231
Oregon Health & Science University
9-May-2006

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