HOME >> BIOLOGY >> NEWS
Olfactory input dominates reproductive behavior in mice

CAMBRIDGE, Mass. -- Scientists at Harvard University have found strong signs that the pheromones driving reproduction and fertility in mice are detected primarily by the nose -- not by the specialized vomeronasal system that many researchers had suspected of receiving and processing the bodily chemicals that govern mating behavior. The unexpected finding may settle an ongoing scientific debate by providing evidence that key reproductive behaviors in mice arise predominantly, if not exclusively, from olfactory input instead of input from the vomeronasal, visual or auditory senses.

The results, from a team led by Harvard biologist Catherine Dulac, appear on the web site of the journal Cell this week, and will be published in the journal's Nov. 18 issue.

"It's always interesting when there is a surprise finding," says Dulac, professor of molecular and cellular biology in Harvard's Faculty of Arts and Sciences and an investigator with the Howard Hughes Medical Institute. "Most biology textbooks now say that pheromones affecting reproductive behavior in non-human mammals are detected by the vomeronasal organ, while the nose processes all other odors. Our work suggests quite convincingly that the mouse nose processes both pheromones and other scents, and in fact provides much or all of the chemosensory input that drives mating."

Dulac and her colleagues made pioneering use of a retrograde pseudorabies virus, which is capable of traveling across the synapses separating neurons but does so in a direction opposite to that in which nerve impulses ordinarily travel. By injecting fluorescently marked virus into a mating center in the mouse hypothalamus -- a collection of neurons that produce luteinizing hormone-releasing hormone (LHRH), which manages the development and function of mammalian gonads -- the scientists could trace backward to find the sensory receptors that first detect pheromones, species- and gender-specific chemical cues that drive anima
'"/>

Contact: Steve Bradt
steve_bradt@harvard.edu
617-496-8070
Harvard University
10-Nov-2005


Page: 1 2 3

Related biology news :

1. Olfactory nerve cells expressing same receptor display a varied set of reactions
2. Olfactory system detects pheromones that control reproduction
3. Olfactory receptor cells may provide clues to psychiatric disease
4. Underwater robots work together without human input
5. Novel asthma study shows multiple genetic input required; single-gene solution shot down
6. Childhood environment influences reproductive function
7. March of Dimes awards $250K prize to stem cell research, reproductive biology pioneers
8. Delayed breeding is not necessarily costly to lifetime reproductive success
9. Universities in San Antonio and Hawaii study safety of assisted reproductive technologies
10. Exposure to dioxins influences male reproductive system, study of Vietnam veterans concludes
11. Conservative forces hampering progress in sexual and reproductive health

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/4/2017)...  CES 2017 – Valencell , the leading ... the launch of two new versions of its ... sensor modules that incorporate the best of Valencell,s ... The two new designs include Benchmark BE2.0, a ... Benchmark BW2.0, a 2-LED version of its original ...
(Date:12/20/2016)... 20, 2016   Valencell , the leading ... STMicroelectronics (NYSE: STM), a global semiconductor leader ... announced today the launch of a new, highly ... that includes ST,s compact SensorTile turnkey ... biometric sensor system. Together, SensorTile and Benchmark deliver ...
(Date:12/15/2016)... and BADEN-BADEN, Germany , December ... leading global financial services provider, today announced an agreement with ... behavioural biometrics, to join forces. The partnership will enable clients ... strategies in compliance with local data protection regulation. ... In order to ...
Breaking Biology News(10 mins):
(Date:1/24/2017)... - BioAmber Inc. (NYSE: BIOA ) announced that, ... the size of the offering by 75% and purchase 3,684,212 ... to purchase 1,842,106 shares of common stock of the Company ... stock (the "Exercise Price"), at a price to the public ... The warrants have a term of four (4) years, exercisable ...
(Date:1/24/2017)... , ... January 24, 2017 , ... ... circumference, and increased serum leptin levels had a positive association with increased prostate ... study published in the International Neurourology Journal involved 571 Korean men who ...
(Date:1/24/2017)... Franklin, MA, USA & Geneva, Switerland (PRWEB) , ... ... ... are pleased to announce the first commercially available malaria Plasmodium falciparum culture panels ... Malaria P. falciparum culture panels, which are available in a range of concentrations ...
(Date:1/24/2017)... , Jan. 24, 2017 /PRNewswire/ - ProMetic Life Sciences ... announced today that its orally active lead drug candidate, ... designation by the UK Medicines and Healthcare Products Regulatory ... A PIM designation is an early ... for the Early Access to Medicines Scheme ("EAMS"), intended ...
Breaking Biology Technology:
Cached News: