HOME >> BIOLOGY >> NEWS
Other highlights in JNCI, June 12

AIDS-Related Cancers Decline with Introduction of Intense Antiretroviral Therapy

Higher immune cell counts in AIDS patients treated with highly active antiretroviral therapy (HAART) are associated a lower incidence of Kaposi sarcoma and non-Hodgkin lymphoma.

AIDS patients are at high risk for Kaposi sarcoma, non-Hodgkin lymphoma, and cervical cancer, but recent studies have found the incidence of Kaposi sarcoma and non-Hodgkin lymphoma has been declining in people with AIDS since the introduction of HAART in 1996. This therapy usually increases the number of patients CD4 cells, also known as helper T-cells, and reduces the risks associated with infectious diseases.

Robert J. Biggar, M.D., of the National Cancer Institute in Bethesda, Md., and colleagues assessed the relationship between cancer incidence and patients CD4 cell counts at the time of AIDS diagnosis by comparing cancer incidence in AIDS patients before and after HAART became available.

After 1996, the incidence of Kaposi sarcoma and non-Hodgkin lymphoma in AIDS patients decreased, while cervical cancer rates in AIDS patients increased. CD4 count was strongly associated with a decrease in Kaposi sarcoma and non-Hodgkin lymphoma rates, but not with cervical cancer rates.

Our results illustrate the variable impact of immunity on the risk of AIDS-associated cancers with the range of CD4 counts in persons with AIDS, the authors write.

Contact: National Cancer Institute Press Office, 301-496-6641, ncipressofficers@mail.nih.gov


Oncogene Overexpression Is Associated with Aggressive Glioma

Researchers have determined that the cell cycle-related kinase gene (CCRK) may be involved in the development of glioblastoma multiforme, the most aggressive form of a type of brain tumor called glioma.

The median survival for patients with glioblastoma multiform
'"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
12-Jun-2007


Page: 1 2 3

Related biology news :

1. Other highlights in the Aug. 7 JNCI
2. Other highlights in the July 24 JNCI
3. Other highlights from the July 10 JNCI
4. Other highlights in JNCI, June 26
5. Other highlights from the June 6 JNCI
6. Other highlights in the May 16 JNCI
7. Other highlights from the April 18 Journal of the National Cancer Institute
8. Other highlights from the March 21 JNCI
9. Other highlights in the March 7 JNCI
10. Other highlights in the Feb. 21 JNCI
11. Other highlights in the Jan. 17 JNCI

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/24/2019)... ... July 24, 2019 , ... ... PhD, a quality assurance expert with more than 20 years of experience working ... products, has joined the firm as an Expert Consultant. , Dr. Hartzfeld has ...
(Date:7/23/2019)... ... , ... NanoFUSE is pleased to announce the ... spine and orthopedic use. Bioactive glass is a calcium phosphate coated silica that ... orthopedics for over 30 years and now NanoFUSE Biologics has used advanced research ...
(Date:7/19/2019)... ... July 19, 2019 , ... ... Amorphous and Crystalline States – Insights from Synchrotron X-ray Pair Distribution (SXPDF) Studies”. ... along with Chris Benmore of Argonne National Laboratory and Gabriel de Araujo of ...
Breaking Biology News(10 mins):
(Date:8/6/2019)... ... August 05, 2019 , ... ... has been recognized as a distinguished leader by PharmaVOICE magazine, earning him a ... article in the magazine’s July/August special issue. , As the executive vice president ...
(Date:7/26/2019)... (PRWEB) , ... July 25, 2019 , ... ... biopharma leaders through off-the-record collaboration and dialogue, today announces its Boston BD ... Waterfront Hotel. As part of Biotech Week Boston , the event provides ...
(Date:7/17/2019)... ... July 15, 2019 , ... CRISPR is often thought ... certain trait can be removed, replaced, or edited, but Yiping Qi, assistant professor in ... these traditional applications in his latest publication in Nature Plants. In this comprehensive review, ...
(Date:7/9/2019)... ... 08, 2019 , ... Today, at the BIO World Congress on ... (NCGA) announced the winners of the Consider Corn Challenge II. Three winners were ... corn to produce biobased materials. , “Corn is a sustainable, abundant and affordable ...
Breaking Biology Technology:
Cached News: