HOME >> BIOLOGY >> NEWS
Other highlights in JNCI, June 26

Finasteride Has Little Impact on Sexual Function in Men

The drug finasteride had a minimal effect on the sexual function of men who took it to prevent prostate cancer.

Some studies have found a link between finasteride and sexual dysfunction in men. But these studies were smaller, short-term, and did not consider variation among individuals when evaluating the impact of finasteride on sexual function.

Carol Moinpour, Ph.D., of the Fred Hutchison Cancer Research Center in Seattle and colleagues investigated sexual dysfunction in more than 17,000 men who participated in the Prostate Cancer Prevention Trial during a 7-year period.

Finasteride only slightly increased sexual dysfunction compared with a group not taking the drug, and the effect decreased over time.

Our data show that the effects of finasteride treatment are clinically far less relevant than natural sources of variability in this heterogeneous population and suggest that finasteride would cause little or no sexual dysfunction for most men who might take it, the authors write.

Contact: Dean Forbes, communications department, Fred Hutchison Cancer Research Center, (206) 667-2896, dforbes@fhcrcc.org


Surrogate Endpoints Inconsistently Used in Clinical Trials

In a commentary, Cornelis Punt, M.D., Ph.D., of the University Nijmegen Medical Center in The Netherlands and colleagues discuss the inconsistent use of surrogate endpoints in clinical trials and propose guidelines for future studies.

Overall survival is considered the gold standard endpoint for cancer treatment trials. But the time and money required to conduct a trial using overall survival as the endpoint has led researchers to consider other endpoints that can act as surrogates for overall survival.

Looking at 52 studies of phase III clinical trials of colon cancer treatment, the
'"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
26-Jun-2007


Page: 1 2 3

Related biology news :

1. Other highlights in the Aug. 7 JNCI
2. Other highlights in the July 24 JNCI
3. Other highlights from the July 10 JNCI
4. Other highlights in JNCI, June 12
5. Other highlights from the June 6 JNCI
6. Other highlights in the May 16 JNCI
7. Other highlights from the April 18 Journal of the National Cancer Institute
8. Other highlights from the March 21 JNCI
9. Other highlights in the March 7 JNCI
10. Other highlights in the Feb. 21 JNCI
11. Other highlights in the Jan. 17 JNCI

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/13/2020)... ... 13, 2020 , ... Acumed LLC today announced that it ... of the Louisville-based company’s orthobiologics portfolio. Under the terms of the agreement, Acumed ... phosphate-based bone allograft (Trabexus) and calcium phosphate-based biocement (Fortera). Vivorte will continue to ...
(Date:3/10/2020)... , ... March 10, 2020 , ... ... Cytonus’ Board of Directors. Dr. Narasimhan is Senior Vice President of Strategic Initiatives, ... of the Board of Directors of Cytonus, we are extremely pleased to welcome ...
(Date:3/5/2020)... ... March 05, 2020 , ... ... of its Scientific Advisory Board (SAB) comprised of the industry’s key opinion ... cell therapy centers, and private industry. Cytonus is a leading cell-based platform ...
Breaking Biology News(10 mins):
(Date:2/28/2020)... (PRWEB) , ... February 26, 2020 , ... ... system combines a high-speed camera with a dedicated controller, thus simplifying setup, ... per second, the HS7 is the first of Fastec Imaging’s new HS Series ...
(Date:2/21/2020)... ... February 20, 2020 , ... The dietary supplement industry ... that what’s listed on an ingredient panel is actually in their product. ... with the adoption of CertainT, which is designed to protect the intellectual property ...
(Date:2/19/2020)... ... February 18, 2020 , ... ... announced the launch of a new and unified global brand identity, as it ... most complex engineering challenges, as well as an enthusiasm for designing and manufacturing ...
(Date:2/11/2020)... , ... February 11, 2020 , ... ... residuals solutions services in North America, today announced that the City of Fort ... to its biosolids management needs. Commencing in April of 2020, Synagro will assume ...
Breaking Biology Technology:
Cached News: