HOME >> BIOLOGY >> NEWS
Other highlights in the Jan. 17 JNCI

Calcium Supplements Offer Prolonged Protection Against Colorectal Adenomas in High-Risk Patients

Previous studies have shown that people with noncancerous colorectal tumors called adenomas who take calcium supplements for 4 years can reduce their risk of an adenoma recurrence. A new study shows that the protective effect of those supplements lasts for up to 5 years after stopping supplementation.

In the Calcium Polyp Prevention Study, 930 people with a recent adenoma were randomly assigned to receive 4 years of daily 1200-milligram calcium supplements or a placebo. The study revealed that those assigned to calcium supplements had a 17 percent lower relative risk of an adenoma recurrence than those who got the placebo.

In the new study, Maria V. Grau, M.D., and John A. Baron, M.D., of Dartmouth Medical School, and colleagues followed 822 of the patients from that trial after the end of the treatment. Their aim was to compare the risk of recurrence among participants who had taken calcium with the risk among those who had taken a placebo.

The researchers found that, in the first 5 years after the end of the treatment, people in the calcium group continued to have a lower risk of adenomas than those in the placebo group: 31.5 percent of people who had taken calcium had recurrences compared with 43.2 percent of those originally in the placebo group. However, after 5 years, this protective effect disappeared.

"Our study provides further evidence of the potential of calcium as a chemopreventive agent against colorectal adenomas among individuals with a history of these tumors," the authors write. "Our data indicate that, in these patients, the protective effect of calcium may extend for up to 5 years after the cessation of active treatment."

"Where do we go from here--and, more important, what public health recommendations related to calcium do we provide for risk reduction of colorectal cancer?" ask ed
'"/>

Contact: Andrea Widener
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
16-Jan-2007


Page: 1 2 3 4 5 6 7

Related biology news :

1. Other highlights in the Aug. 7 JNCI
2. Other highlights in the July 24 JNCI
3. Other highlights from the July 10 JNCI
4. Other highlights in JNCI, June 26
5. Other highlights in JNCI, June 12
6. Other highlights from the June 6 JNCI
7. Other highlights in the May 16 JNCI
8. Other highlights from the April 18 Journal of the National Cancer Institute
9. Other highlights from the March 21 JNCI
10. Other highlights in the March 7 JNCI
11. Other highlights in the Feb. 21 JNCI

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/27/2018)... ... November 27, 2018 , ... ... have worked together to integrate the LabArchives Classroom Edition with Current Protocols Essential ... will be available beginning January of 2019. , The integration of ...
(Date:11/20/2018)... (PRWEB) , ... November 19, 2018 , ... ... by Applications (academic research tools, drug development, agriculture, human clinical therapeutics, and animal ... breeding products), by Technology (drug compound and target screening, and agriculture and industrial ...
(Date:11/20/2018)... ... November 20, 2018 , ... Like many large breed dogs, Jack, a ... was a year old, his mom, Rebecca, noticed he was slow to get up ... veterinarian and her suspicions were confirmed: Jack had bilateral hip dysplasia, a congenital condition ...
Breaking Biology News(10 mins):
(Date:11/11/2018)... ... 09, 2018 , ... Triple W, an innovator of connected health devices, today ... for DFree ®, the first health tech wearable device for incontinence that monitors ... the bathroom. The announcement was made during CES Unveiled New York, an invite-only tech ...
(Date:11/7/2018)... , ... November 07, 2018 , ... ... been leading a campaign to increase awareness of the adult tissue stem cell ... the month of November, the company is intensifying this effort with new educational ...
(Date:11/5/2018)... ... November 05, 2018 , ... ... backed by Siemens Healthineers and several healthcare VC firms announces at Distributed Health ... making a history by purchasing tokens and obtaining its first radiology interpretations, one ...
(Date:11/3/2018)... ... ... Triangle Insights Group, a premier life sciences consulting firm, announced today that ... the United States, appearing on this year’s Inc. 5000 list. Since its inception ... over the previous three years. , Separately, Triangle Insights was also ranked on ...
Breaking Biology Technology:
Cached News: