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Other highlights in the March 15 JNCI

Dietary Folate Intake Associated with Reduced Pancreatic Cancer Risk

High dietary folate intake may be associated with a reduced risk of pancreatic cancer, a new study suggests. However, supplemental folate intake was not associated with pancreatic cancer risk.

Susanna C. Larsson, M.Sc., of the Karolinska Institute in Stockholm, Sweden, and colleagues gave a food and diet questionnaire to 81,922 cancer-free men and women enrolled in the Swedish Mammography Cohort and Cohort of Swedish Men. They followed these men and women for an average of 6.8 years, and observed 135 cases of pancreatic cancer during that time.

Men and women whose dietary intake of folate was equal to or above 350 micrograms a day had a lower incidence of pancreatic cancer than men and women whose dietary intake of folate was less than 200 micrograms a day. They calculated that there would be 41 cases per 100,000 people who consumed the lowest amounts of folate and 18 cases per 100,000 people among those consuming the most folate. The authors suggest increased dietary folate intake may be associated with a reduced risk of pancreatic cancer.

Contact: Susanna Larsson, Karolinska Institute, 46-8-524-860-59, susanna.larsson@ki.se

Study Examines Childhood Leukemia Incidence and Its Association with Influenza

A new study has found that small peaks in the annual rates of childhood acute lymphoblastic leukemia (ALL) in Britain immediately followed influenza epidemics. The finding supports the hypothesis that some childhood leukemia may be triggered by an infection occurring close to the time of diagnosis.

Mary Kroll, M.Sc., and colleagues at Oxford University, studied time trends of childhood leukemia diagnosed from 1974-2000 in England, Scotland, and Wales, using data from the National Registry of Childhood Tumors.

There was a gradual increase in the incidence of childhood ALL bet
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Contact: Ariel Whitworth
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
14-Mar-2006


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