HOME >> BIOLOGY >> NEWS
Pairing nanoparticles with proteins

UPTON, NY -- In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays. The nanoparticles and methods to create nanoparticle-protein complexes can be used to help decipher protein structures, to identify functional parts of proteins, and to "glue" together new protein complexes. Applications envisioned by the researchers include catalysts for converting biomass to energy and precision "vehicles" for targeted drug delivery.

The research, which was conducted at the U.S. Department of Energy's Brookhaven National Laboratory, will be published in the July 2, 2007 issue of the journal Angewandte Chemie.

"Our study demonstrates that nanoparticles are appealing templates for assembling functional biomolecules with extensive potential impact across the fields of energy conversion, structural biology, drug delivery, and medical imaging," said lead author Minghui Hu, a postdoctoral student working with James Hainfeld, Raymond Brinas, Luping Qian, and Elena Lymar in the Biology Department at Brookhaven Lab.

In the field of energy conversion, scientists have been searching for efficient ways to convert organic fuels such as ethanol into electricity using catalytic electrodes. But making single layers of densely packed enzymes, the functional part of such catalytic electrodes, has been a challenge. This new research shows that precisely engineered gold nanoparticles can be used to "glue" enzymes together to form oriented and ordered single layers, and that these monolayers are mechanically stable enough to be transferred onto a solid surface such as an electrode.

For this research, the scientists attached gold nanoparticles to an enzyme complex that helps drug-resistant tuberculosis bacteria survive, which has been studied by Brookhaven Lab biologist Huilin Li. The researcher
'"/>

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory
27-Jun-2007


Page: 1 2 3

Related biology news :

1. Gold nanoparticles may pan out as tool for cancer diagnosis
2. Under magnetic force, nanoparticles may deliver gene therapy
3. UCSB researchers show how to make polymeric micro- and nanoparticles
4. In nature, proteins sweep up nanoparticles
5. Bacteria ferry nanoparticles into cells for early diagnosis, treatment
6. MU researchers examine the environmental effects of silver nanoparticles
7. Work with nanoparticles may lead to on-the-spot virus detector
8. Widely used iron nanoparticles exhibit toxic effects on neuronal cells
9. Test finds manufactured nanoparticles dont harm soil ecology
10. DNA nanoparticles hold promise in gene therapy for Parkinsons disease
11. MIT develops nanoparticles to battle cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... to expand at a CAGR of 25.76% during the ... is the primary factor for the growth of the ... https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global stem ... technology, application, and geography. The stem cell market of ...
(Date:3/30/2017)... 2017 Trends, opportunities and forecast in this ... technology (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, ... end use industry (government and law enforcement, commercial and ... and others), and by region ( North America ... Asia Pacific , and the Rest of the ...
(Date:3/24/2017)... Research and Markets has announced the addition of the ... Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle Access ... 15.1% over the next decade to reach approximately $1,580 million by ... and forecasts for all the given segments on global as well ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... ... accelerate pharmaceutical and biotherapeutics development, announces the launch of the new NHS ... to gain kinetic binding data for a wide range of molecules, including small ...
(Date:8/15/2017)... (PRWEB) , ... August 15, 2017 , ... The ... time on Immuno-Oncology 360° (IO360°) programming through a series of upcoming panels and events. ... February 7-9, 2018, at The Roosevelt Hotel in New York City. , “With our ...
(Date:8/14/2017)... Portland, Oregon (PRWEB) , ... August 14, 2017 ... ... modules that provide essential device-to-computer interconnect using USB or PCI Express, announced the ... hardware. , SYZYGY is intended to satisfy the need for a compact, low ...
(Date:8/11/2017)... ... ... Algenist continues to disrupt the skincare industry with today’s debut of GENIUS Liquid ... the key structural element skin needs to maintain its youthful appearance and Algenist is ... First to market with proprietary collagen water active , Active ...
Breaking Biology Technology:
Cached News: