HOME >> BIOLOGY >> NEWS
Pairing nanoparticles with proteins

UPTON, NY -- In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays. The nanoparticles and methods to create nanoparticle-protein complexes can be used to help decipher protein structures, to identify functional parts of proteins, and to "glue" together new protein complexes. Applications envisioned by the researchers include catalysts for converting biomass to energy and precision "vehicles" for targeted drug delivery.

The research, which was conducted at the U.S. Department of Energy's Brookhaven National Laboratory, will be published in the July 2, 2007 issue of the journal Angewandte Chemie.

"Our study demonstrates that nanoparticles are appealing templates for assembling functional biomolecules with extensive potential impact across the fields of energy conversion, structural biology, drug delivery, and medical imaging," said lead author Minghui Hu, a postdoctoral student working with James Hainfeld, Raymond Brinas, Luping Qian, and Elena Lymar in the Biology Department at Brookhaven Lab.

In the field of energy conversion, scientists have been searching for efficient ways to convert organic fuels such as ethanol into electricity using catalytic electrodes. But making single layers of densely packed enzymes, the functional part of such catalytic electrodes, has been a challenge. This new research shows that precisely engineered gold nanoparticles can be used to "glue" enzymes together to form oriented and ordered single layers, and that these monolayers are mechanically stable enough to be transferred onto a solid surface such as an electrode.

For this research, the scientists attached gold nanoparticles to an enzyme complex that helps drug-resistant tuberculosis bacteria survive, which has been studied by Brookhaven Lab biologist Huilin Li. The researcher
'"/>

Contact: Karen McNulty Walsh
kmcnulty@bnl.gov
631-344-8350
DOE/Brookhaven National Laboratory
27-Jun-2007


Page: 1 2 3

Related biology news :

1. Gold nanoparticles may pan out as tool for cancer diagnosis
2. Under magnetic force, nanoparticles may deliver gene therapy
3. UCSB researchers show how to make polymeric micro- and nanoparticles
4. In nature, proteins sweep up nanoparticles
5. Bacteria ferry nanoparticles into cells for early diagnosis, treatment
6. MU researchers examine the environmental effects of silver nanoparticles
7. Work with nanoparticles may lead to on-the-spot virus detector
8. Widely used iron nanoparticles exhibit toxic effects on neuronal cells
9. Test finds manufactured nanoparticles dont harm soil ecology
10. DNA nanoparticles hold promise in gene therapy for Parkinsons disease
11. MIT develops nanoparticles to battle cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/27/2019)... ... November 26, 2019 , ... Personalized Stem Cells, Inc (“PSC”), a ... Foundation and hosted by Dr. Steven Sampson and Dr. Danielle Aufiero of the ... 23, 2019, highlighted the ongoing efforts to promote research, educate the public, and provide ...
(Date:11/22/2019)... ... November 21, 2019 , ... The inventors of ... have announced a major step forward with that therapy, known as SurVaxM. MimiVax ... company, spun off from Roswell Park in 2012, has entered into a China-exclusive ...
(Date:11/19/2019)... ... ... Project Lifeline – a community partnership and research program initiated ... use disorder (SUD) – will take center stage at the upcoming NACDS ... in preventing and treating opioid abuse in Blair County, Pennsylvania, will receive the NACDS ...
Breaking Biology News(10 mins):
(Date:10/30/2019)... ... October 30, 2019 , ... ... the many roles innovation and technology play in educating the next generation of ... hands-on learning opportunities and presentations by WesternU administrators and representatives of companies working ...
(Date:10/29/2019)... ... October 29, 2019 , ... Researchers ... Using Silios CMS-C multispectral imagers , researchers identified people by the image ... based on retinal imaging, face recognition, fingerprints and vasculature. , The new ...
(Date:10/22/2019)... ... October 22, 2019 , ... Catalent, a global leader in clinical supply services, ... Integration, will participate in a panel session titled “Cell and Gene Therapy Logistics” at ... Gwen Hotel, Chicago, on Oct. 28-30, 2019. , The panel session, on Wednesday, Oct. ...
(Date:10/17/2019)... PARK, Kan. (PRWEB) , ... October 15, 2019 ... ... to 23andMe, a leader among services that offer DNA Testing for health and/or ... so popular. Everywhere you look, it seems that people want to know more ...
Breaking Biology Technology:
Cached News: