East Hills, NY (October 28, 2005) - - As avian flu concerns extend across the globe, governments and pharmaceutical manufacturers face potentially huge demand for vaccines. According to public health experts, current production capacity and response times would not suffice in the event of a pandemic. Viral vaccine development is governed by stringent regulatory controls and can take as long as eight to 12 years costing anywhere from $300 to $800 million USD. In a presentation at the 10th annual China International Pharmaceutical Industry Exhibition in Shanghai, Ian Sellick of Pall Corporation (NYSE: PLL) described how the use of disposable and scalable technologies to purify large molecule vectors, such as for flu vaccines, can help manufacturers streamline the process and overcome many of the unique challenges associated with vaccine development.

Sellick's presentation reviewed advanced approaches to purification as part of a total process management scheme to help vaccine manufacturers address issues of scalability, validation and process development. Disposable processing systems can be installed in practically every part of the vaccine development cycle from cell fermentation and harvesting to downstream processing steps. Disposables offer lower installation costs compared to stainless steel systems and eliminate cleaning and cleaning validation. These factors significantly lower labor and maintenance costs and reduce the time required for scale-up procedures. Disposables also reduce the risk of cross-batch contamination and of worker exposure to the biohazards inherent in vaccine development.

"The use of scalable and disposable technologies can significantly improve process economics by eliminating time-consuming steps, safety risks, and several sources of capital and recurring expenses," said Sellick. "Efficient vaccine production requires flexibility and scalability, and current fears of an avian flu pandemic only increase the need for
'"/>

Contact: Marcia Katz
marcia_katz@pall.com
516-801-9128
Pall Corporation
28-Oct-2005

Page: 1 2 3
Related biology news :

1. Reify Corporations Visible Discovery(tm) technology showcased at ICSB conference
2. Progenika Biopharma presents a biochip that guarantees safety in blood transfusions
3. SNM presents awards on Capitol Hill
4. ESA presents the sharpest ever satellite map of Earth
5. New book presents neurobiology from an evolutionary perspective
6. Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants
7. Childrens Hospital and Research Center-Oakland presents a new maternal diet study
8. USGS presents a world of science at GSA in Philadelphia
9. Childrens Hospital Boston presents at the 2006 American Academy of Pediatrics National Conference
10. DFG presents the 2006 MAK and BAT value list
11. Childrens Hospital Boston presents at the 2006 Pediatric Academic Societies annual meeting