HOME >> BIOLOGY >> NEWS
Parasite whips up ideas for bowel cancer treatments

A study of how the body expels parasitic worms has led to a surprising new discovery about the immune system that could help in the treatment of bowel cancer.

Scientists investigating whipworms, parasites that infect one-fifth of the world's population as well as livestock and domestic animals, have discovered a new way that the body effectively eliminates the parasites.

The University of Manchester research, published in the US journal Science, found the reason why some hosts were able to expel the worms naturally without the need for treatment.

"This is a completely new way in which the immune system controls disease and may lead scientists to look at new ideas in the treatment of inflammatory bowel diseases and even bowel cancer," said Dr Laura Cliffe in the Faculty of Life Sciences, who carried out the research.

"During our investigations we discovered that the immune system does more than what it currently says in the text books it controls other physiological systems.

"The body naturally renews the lining of the gut every few days as cells rise to the surface and are discarded. The whipworm attaches itself to the lining and then must burrow faster than the rate of cell renewal in order to remain in the gut, similar to walking the wrong way down an escalator.

"What we found is that hosts whose bodies generated a good allergic response to the worms were able to increase the rate of cell renewal in the intestine and force the parasites to the surface and out through the normal channels.

Human whipworm (trichuris trichiura) is a 3cm-to-5cm-long nematode or roundworm that gets its name from its whip-like shape. Once inside their host, adult worms produce eggs that are passed in the faeces and mature in the soil.

If the eggs are ingested, they hatch in the large intestine where they can cause trichuriasis, a disease most common in warm, humid climates, including much of the developing world but also s
'"/>

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester
16-Jun-2005


Page: 1 2

Related biology news :

1. Parasites impact goes beyond host to affect ecosystem
2. Evolutionary first: Parasite reaches beyond host to play havoc with others sex lives
3. Parasites trigger healthy eating in caterpillars
4. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
5. Story ideas from Molecular & Cellular Proteomics
6. Story ideas from the Journal of Lipid Research
7. Story ideas from the Journal of Biological Chemistry
8. Story ideas from the Journal of Lipid Research
9. Symposium will explore sciences next great ideas
10. Agriculture and tropical conservation: rethinking old ideas
11. Agreement to increase the flow of ideas from laboratory to clinic

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/29/2019)... ... , ... Lajollacooks4u has expanded its team as it gears up for a ... seen record growth in 2019, having hosted a multitude of team-building events and cooking ... visited the company’s La Jolla-based venue, and Lajollacooks4u has worked hard to accommodate the ...
(Date:8/27/2019)... Fla. (PRWEB) , ... August 27, 2019 , ... ... in life science and drug development. This episode is scheduled to broadcast 4Q/2019. ... explore Debiopharm, a biopharmaceutical research, development, investment and manufacturing company. The show will ...
(Date:8/21/2019)... ... August 20, 2019 , ... Cutting Edge ... for the spine, today announced the 510(K) clearance of its novel SI joint ... is proven to improve osseointegration through superior hydrophilicity and optimized surface chemistry, as ...
Breaking Biology News(10 mins):
(Date:9/4/2019)... , ... September 03, 2019 ... ... of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, gene ... Science & Technology will present at the upcoming Nordic Life Science Days ...
(Date:8/27/2019)... ... 27, 2019 , ... Dr. Kim Carlson is a veterinary surgeon practicing in ... Surgical Group , a new surgical practice in San Mateo. She is currently ... more veterinary specialists as the practice grows. , When asked about the opening of ...
(Date:8/15/2019)... (PRWEB) , ... August 15, 2019 , ... ... Scientific Advisory Board. Mr. Lawrence is a member of the Institute of Food ... Safety and Health (IFSH) Advisory Board, Joint Institute for Food Safety and Applied ...
(Date:8/6/2019)... ... August 06, 2019 , ... The San Diego Biotechnology ... the biweekly SDBN BUZZ podcast focused on connecting the region’s biotech community and ... to promote the region and attract external employers, investors, scientists, and others who ...
Breaking Biology Technology:
Cached News: