HOME >> BIOLOGY >> NEWS
Parasite whips up ideas for bowel cancer treatments

A study of how the body expels parasitic worms has led to a surprising new discovery about the immune system that could help in the treatment of bowel cancer.

Scientists investigating whipworms, parasites that infect one-fifth of the world's population as well as livestock and domestic animals, have discovered a new way that the body effectively eliminates the parasites.

The University of Manchester research, published in the US journal Science, found the reason why some hosts were able to expel the worms naturally without the need for treatment.

"This is a completely new way in which the immune system controls disease and may lead scientists to look at new ideas in the treatment of inflammatory bowel diseases and even bowel cancer," said Dr Laura Cliffe in the Faculty of Life Sciences, who carried out the research.

"During our investigations we discovered that the immune system does more than what it currently says in the text books it controls other physiological systems.

"The body naturally renews the lining of the gut every few days as cells rise to the surface and are discarded. The whipworm attaches itself to the lining and then must burrow faster than the rate of cell renewal in order to remain in the gut, similar to walking the wrong way down an escalator.

"What we found is that hosts whose bodies generated a good allergic response to the worms were able to increase the rate of cell renewal in the intestine and force the parasites to the surface and out through the normal channels.

Human whipworm (trichuris trichiura) is a 3cm-to-5cm-long nematode or roundworm that gets its name from its whip-like shape. Once inside their host, adult worms produce eggs that are passed in the faeces and mature in the soil.

If the eggs are ingested, they hatch in the large intestine where they can cause trichuriasis, a disease most common in warm, humid climates, including much of the developing world but also s
'"/>

Contact: Aeron Haworth
aeron.haworth@manchester.ac.uk
44-161-275-8383
University of Manchester
16-Jun-2005


Page: 1 2

Related biology news :

1. Parasites impact goes beyond host to affect ecosystem
2. Evolutionary first: Parasite reaches beyond host to play havoc with others sex lives
3. Parasites trigger healthy eating in caterpillars
4. 2007 EURYI: 20 young researchers to receive Nobel Prize-sized awards for breakthrough ideas
5. Story ideas from Molecular & Cellular Proteomics
6. Story ideas from the Journal of Lipid Research
7. Story ideas from the Journal of Biological Chemistry
8. Story ideas from the Journal of Lipid Research
9. Symposium will explore sciences next great ideas
10. Agriculture and tropical conservation: rethinking old ideas
11. Agreement to increase the flow of ideas from laboratory to clinic

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/1/2020)... ... July 01, 2020 , ... ... and solutions for glioblastoma—the most common and aggressive adult brain cancer—announced today the ... PhD. Senior Fellows are charged with supporting the organization’s initiatives and overall vision. ...
(Date:6/23/2020)... ... June 23, 2020 , ... First ... Renovagen Ltd, a UK supplier and manufacturer of innovative portable renewable energy equipment, ... in the fight against the COVID-19 pandemic in Zambia. , One of Renovagen’s ...
(Date:6/19/2020)... ... June 18, 2020 , ... ... for Data Decisions,” for pharmaceutical and biotech executives, laboratory managers, scientists, researchers ... scientific instruments and laboratory equipment from dozens of manufacturers into their lab. ...
Breaking Biology News(10 mins):
(Date:7/18/2020)... ... July 16, 2020 , ... After research model surgery and catheter ... great surgery is only the beginning of a successful study, while protecting and accessing ... Brad Gien, Global Head of Surgery from Envigo in a live ...
(Date:7/18/2020)... ... July 17, 2020 , ... ... for the life sciences and food industries, is pleased to announce that Charles ... Research – Business Development. , Charles is an accomplished and results-driven sales executive ...
(Date:7/10/2020)... HONG KONG (PRWEB) , ... July 09, 2020 ... ... chemical compound called 1-phenyl-2-thiourea (PTU) is commonly used to suppress pigment formation in ... years, the PolyU research team led by Dr MA has been using the ...
(Date:7/7/2020)... ... July 06, 2020 , ... ... from Roche, Eli Lilly, Bristol-Myers Squibb, the University of Chicago, Massachusetts General Hospital, ... has hosted an elite awards program, highlighting outstanding examples of how technology innovations ...
Breaking Biology Technology:
Cached News: