HOME >> BIOLOGY >> NEWS
Parasitic worms used to fight bowel disease

EAST LANSING, Mich. Although most of us cringe at the sound of the words "parasitic worms," it's a fact that some of these creatures are actually good for us.

At Michigan State University, researcher Linda Mansfield is part of a national team of scientists investigating the role that parasites can play in treating inflammatory bowel disease, or IBD, in humans.

Her research is part of a more than $10 million National Institutes of Health grant supporting the Food and Waterborne Diseases Integrated Research Network of laboratories launched by the National Institutes of Allergy and Infectious Diseases.

Some researchers argue that improved hygiene throughout the developed world may be responsible for inflammatory bowel disease, as well as a whole range of autoimmune disorders. According to this "hygiene hypothesis," immune systems require exposure to infections of all sorts early in life in order to develop sufficiently.

Intriguingly, inflammatory bowel disease, which has two forms Crohn's disease and ulcerative colitis is virtually unknown in the developing world, while it is increasing dramatically in developed societies. When people from developing countries move to developed ones, their incidence of the disease tends to increase.

"We know from veterinary medicine that many bacterial and protozoan pathogens, especially those that multiply inside of cells, elicit an immune response in the host that would normally cause inflammation, but that worm parasites mount an anti-inflammatory defense that modulates it," said Mansfield, a professor of large animal clinical sciences. "The greater the immune response, the greater the anti-inflammatory effect.

"It's possible that the human immune system developed in a way that is dependent on parasitic worms to regulate immune responses."

The particular worm that Mansfield and colleagues are studying as a potential treatment is known as the whipworm,
'"/>

Contact: Tom Oswald
oswald@msu.edu
517-432-0920
Michigan State University
25-May-2006


Page: 1 2

Related biology news :

1. Parasitic plants sniff out hosts
2. Proteins linked to cancer prevention in humans affect aging in worms
3. Starvation response in worms points to common hunger pathway
4. Carbon nanotube absorption measured in worms, cancer cells
5. Plant cells black out when eaten by leafworms
6. Teaching worms good taste: Researcher reveals the cell biology of learning at ASCB meeting
7. Regenerating worms help elucidate stem cell biology
8. Evolutionary conservation of a mechanism of longevity from worms to mammals
9. Deep sea buffet for bone-devouring worms
10. Allergy-busting worms, cold water corals and the science of Irishness
11. Fluorescing lab worms signal longer life spans, reports CU-Boulder team

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/19/2017)... Jan. 19, 2017 Sensory Inc ... and security for consumer electronics, and i ... systems and cybersecurity solutions, today announced a global ... financial institutions worldwide to bolster security of data ... secure user authentication platforms they offer, innerCore now ...
(Date:1/13/2017)... WASHINGTON, N.Y. , Jan. 13, 2017 /PRNewswire/ ... of technology solutions for the homecare industry, including ... of homecare industry expert, Justin Jugs, as Senior ... brings more than 15 years of homecare experience ... team in developing strategic plans to align Sandata,s ...
(Date:1/12/2017)... Oregon and PUNE, India , January 12, 2017 /PRNewswire/ ... Market: Opportunities and Forecasts, 2015 - 2022," projects that the global biometric technology market ... of 19.4% from 2016 to 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:2/21/2017)... ... February 21, 2017 , ... Vortex ... , a fully automated benchtop system for collecting intact circulating tumor cells (CTCs) ... at the Molecular Medicine Tri Conference (Tri-Con) Annual Meeting 2017 (February 19–24 San ...
(Date:2/21/2017)... , ... February 21, 2017 , ... ... that Dr. Trevor Heritage has joined its executive team to lead the development ... to provide insights to help improve the diagnosis and treatment of cancer. The ...
(Date:2/21/2017)... ... February 21, 2017 , ... ... pair its $200M operational capacity with its strategic internal leadership to provide ... affecting quality and operational management. With office locations in North Carolina, ...
(Date:2/21/2017)... (PRWEB) , ... February 21, 2017 , ... ... creating transformative design and manufacturing solutions for original equipment manufacturers (OEMs) , today ... 2017 marks Creation Technologies’ third consecutive year winning in its category of electronics ...
Breaking Biology Technology:
Cached News: