HOME >> BIOLOGY >> NEWS
Patient's generosity after death leads to possible clues for lung disease

PITTSBURGH Thanks in large part to a dying patient's generosity, researchers have for the first time begun to analyze the progression of idiopathic pulmonary fibrosis (IPF), a degenerative illness distinguished by lung inflammation, scarring and diminished breathing capacity that typically leads to death within about five years of diagnosis. The project, involving the examination of lung tissue recovered shortly after death in a process called warm autopsy, is described by University of Pittsburgh School of Medicine researchers in the June issue of PLoS Medicine, an online journal of the Public Library of Science.

"Up until now, what we have been able to do has been limited by the lack of availability of lung tissue for study," said Naftali Kaminski, M.D., director of the Dorothy P. & Richard P. Simmons Center for Interstitial Lung Disease in the division of pulmonary, allergy and critical care medicine at the University of Pittsburgh School of Medicine and senior author of the PLoS essay, "Lessons from Our Patients: Development of a Warm Autopsy Program."

Warm autopsy a practice involving retrieval of organs within six hours of death has been in use for more than 25 years, chiefly in the study of Alzheimer's disease and multiple sclerosis. However, the University of Pittsburgh's program, which began at the suggestion of an IPF patient, is among the first to use the technique for lung disease research. "Obtaining such prompt access to the organs will, we hope, allow us to approximate disease conditions in a living patient," said Kathleen Oare Lindell, R.N., clinical nurse specialist at the Simmons Center and the essay's first author. "The goal is to learn as much as we can about how IPF works."

Some 5 million people worldwide and 200,000 in the United States are affected by pulmonary fibrosis. Some known causes of pulmonary fibrosis include occupational and environmental exposure to asbestos, metal dust, farming chemicals and mold, an infla
'"/>


5-Jun-2006


Page: 1 2 3

Related biology news :

1. Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
2. Brains hearing center may reorganize after implant of cochlear device
3. Expert to provide update after worst tomato virus hits California
4. Losing weight after pregnancy -- diet and exercise better than diet alone
5. Cardiac patches stimulate regeneration, improve function after heart attack
6. Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer
7. First baby is born after oocytes were matured in the lab and frozen
8. Marker predicts pancreatic cancer outcome after surgery, Jefferson surgeon finds
9. Fever after smallpox vaccination tied to individual genetic variations
10. Children born after PGD as healthy as those born after conventional IVF treatment
11. Lung and bladder cancer deaths continue decades after arsenic exposure

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... MONICA, Calif. , April 13, 2017 ... New York will feature emerging and evolving ... Summits. Both Innovation Summits will run alongside the expo ... of speaker sessions, panels and demonstrations focused on trending ... coast,s largest advanced design and manufacturing event will take ...
(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/5/2017)... Today HYPR Corp. , leading innovator ... of the HYPR platform is officially FIDO® Certified ... architecture that empowers biometric authentication across Fortune 500 enterprises ... over 15 million users across the financial services industry, ... product suites and physical access represent a growing portion ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... for two-dimensional representations of a complex biological network, a depiction of a system ... big mess,” said Dmitry Korkin, PhD, associate professor of computer science at Worcester ...
(Date:10/12/2017)... ... ... AMRI, a global contract research, development and manufacturing organization ... quality of life, will now be offering its impurity solutions as a stand-alone ... for all new drug products, including the finalization of ICH M7 earlier this ...
(Date:10/11/2017)... USA (PRWEB) , ... October 11, 2017 , ... ComplianceOnline’s ... take place on 7th and 8th June 2018 in San Francisco, CA. The Summit ... as well as several distinguished CEOs, board directors and government officials from around the ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: