Penn receives grant for initiative to help understand genes' effects on medications

(Philadelphia, PA) The University of Pennsylvania School of Medicine has been awarded a major grant from the National Institutes of Health (NIH) to bring together researchers from different disciplines to study gene-drug interactions. The three-year, $595,000 award is one of 21 in the country that will support planning activities for groups of researchers to develop interdisciplinary strategies to solve significant biomedical or behavioral research problems.

The Penn project, to be headed by Stephen E Kimmel, MD, Associate Professor of Medicine and Epidemiology, will also establish a new interdisciplinary field called Human Pharmacogenomic Epidemiology (HPE). HPE will bring together the disciplines of genetics, bioinformatics, pharmacology, epidemiology, biostatistics, and bioethics. But HPE is not simply the merger of multiple disciplines, working in parallel or sequence, but rather a new archetype of research that will develop novel ways of working synergistically to address the scientific, logistical, and intellectual barriers to interdisciplinary research. Recent advances have paved the way for significant gains in understanding how genetic variability can alter drug response. Despite this promise, the nature of gene-drug interactions is complex, and progress in the field has been hampered by the lack of a genuine interdisciplinary approach.

"Biomedical research has been typically grouped into separate, departmentally based specialties, often functioning independently of each other," explains Kimmel. "But it has become clear that progress in medicine is a dynamic, multi-faceted process. The conventional divisions within biomedical research may hamper the pace of scientific discovery and ultimately, deliverable benefits to patients. This problem is particularly relevant in our understanding of the influence that genes have on the response to medications. This award will expand the range of study into an exceedingly important biomedical problem and t

Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Page: 1 2 3

Related biology news :

1. Carnegie Mellons Peter Adams receives EPA research grant
2. Philadelphia ecologist receives top Mongolia honor
3. VIB scientist receives major research grant
4. Maynard Olson receives $500,000 Gruber Genetics Prize
5. University of Cincinnati receives $1.7M to research molecular treatment of brain injury
6. Wright State scientist receives grant to help clean up polluted American harbors
7. UCR biologist receives $1.75 million grant to study plant-threatening bacteria
8. Michael R. Zalutsky receives SNMs 2007 Paul C. Aebersold Award
9. Nobel laureate James Watson receives personal genome in ceremony at Baylor College of Medicine
10. MBL scientist Julie Huber receives 2007 LOral USA Fellowship for Women in Science
11. Weill Cornell pharmacologist receives prestigious NIH MERIT Award

Post Your Comments:

(Date:8/26/2020)... (PRWEB) , ... August 25, ... ... clinical-stage biotechnology company developing novel pharmaceuticals targeting mitochondria, in partnership with Essex ... enrolment in its pivotal U.S. Phase 3 VISTA-2 study of SkQ1 ophthalmic ...
(Date:8/21/2020)... ... August 18, 2020 , ... ... today announced that the U.S. Food and Drug Administration (FDA) has approved the ... SBI-101, for the treatment of severe COVID-19. Approval of this IND allows Sentien ...
(Date:8/12/2020)... , ... August 11, 2020 , ... ... based in Princeton, NJ, have entered into license agreements with Housey Pharma’s HMI ... Both Roche and J&J have annual Research and Development spending in excess ...
Breaking Biology News(10 mins):
(Date:7/31/2020)... ... July 29, 2020 , ... eSource has long been touted ... will cover the history of eSource, the reasons it did not take off as ... to site source, the industry is moving towards capturing data electronically for clinical trials ...
(Date:7/22/2020)... , ... July 22, 2020 , ... Join experts from ... Lorenc, Sr. Manager Regulatory Solutions, in a one hour live webinar on ... regulating body in China for drugs and medical devices. Specifically, for medical devices, the ...
(Date:7/18/2020)... ... July 16, 2020 , ... Medial EarlySign ... detection and prevention of high-burden diseases, and Centric Consulting, a business and technology ... to utilize existing data in order to identify and prioritize patients for care. ...
(Date:7/10/2020)... ... July 09, 2020 , ... ... Technology (MIT) has expanded the company’s exclusive license to include clinical applications ... point-of-care diagnostic market, focusing initially on the SARS-CoV-2 biosensor. CANARY’s™ fast ...
Breaking Biology Technology:
Cached News: