HOME >> BIOLOGY >> NEWS
Penn study finds hyperbaric oxygen treatments mobilize stem cells

According to a study to be published in the American Journal of Physiology-Heart and Circulation Physiology, a typical course of hyperbaric oxygen treatments increases by eight-fold the number of stem cells circulating in a patient's body. Stem cells, also called progenitor cells are crucial to injury repair. The study currently appears on-line and is scheduled for publication in the April 2006 edition of the American Journal.

Stem cells exist in the bone marrow of human beings and animals and are capable of changing their nature to become part of many different organs and tissues. In response to injury, these cells move from the bone marrow to the injured sites, where they differentiate into cells that assist in the healing process. The movement, or mobilization, of stem cells can be triggered by a variety of stimuli including pharmaceutical agents and hyperbaric oxygen treatments. Where as drugs are associated with a host of side effects, hyperbaric oxygen treatments carry a significantly lower risk of such effects.

"This is the safest way clinically to increase stem cell circulation, far safer than any of the pharmaceutical options," said Stephen Thom, MD, Ph.D., Professor of Emergency Medicine at the University of Pennsylvania School of Medicine and lead author of the study. "This study provides information on the fundamental mechanisms for hyperbaric oxygen and offers a new theoretical therapeutic option for mobilizing stem cells."

"We reproduced the observations from humans in animals in order to identify the mechanism for the hyperbaric oxygen effect," added Thom. "We found that hyperbaric oxygen mobilizes stem/progenitor cells because it increases synthesis of a molecule called nitric oxide in the bone marrow. This synthesis is thought to trigger enzymes that mediate stem/progenitor cell release."

Hopefully, future study of hyperbaric oxygen's role in mobilizing stem cells will provide a wide array of treatments for combat
'"/>

Contact: Rick Cushman
rick.cushman@uphs.upenn.edu
215-349-5659
University of Pennsylvania School of Medicine
28-Dec-2005


Page: 1 2

Related biology news :

1. New study warns limited carbon market puts 20 percent of tropical forest at risk
2. Clones on task serve greater good, evolutionary study shows
3. Pollution causes 40 percent of deaths worldwide, study finds
4. A study by the MUHC and McGill University opens a new door to understanding cancer
5. New study suggests Concord grape juice may provide protection against breast cancer
6. Preclinical study links gene to brain aneurysm formation
7. In limiting life span, study finds booming bacteria innocent
8. Multicenter study nets new lung tumor-suppressor gene
9. MIT study: Maturity brings richer memories
10. Chickadee, nutchatch presence in conifers increases tree growth, says CU-Boulder study
11. Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/21/2019)... , ... May 20, 2019 , ... ... health care field, today announced a 96.15% pass rate for first-time test takers ... This surpasses the national average of 76.43% by nearly 20 points. , ...
(Date:5/16/2019)... (PRWEB) , ... May 16, 2019 , ... SFC ... as part of the Industry Development and Discovery Partnership that was awarded to SFC ... of a single integrated pod artificial pancreas (AP) system for people with type 1 ...
(Date:5/14/2019)... ... May 13, 2019 , ... BioMedGPS ... a very special Pre-EWMA 2019 event at Gothenburg’s Universeum Aquarium. Guests will be ... and Innovations in Advanced Wound Care. , SmartTRAK’s Advanced Wound Care Experts will ...
Breaking Biology News(10 mins):
(Date:4/8/2019)... ... 08, 2019 , ... US Capital Global Securities , an affiliate of ... in the privately held pharmaceutical company, S1 Biopharma (“S1”). , S1 has a pipeline ... hypoactive sexual dysfunction disorder and is ready to begin phase 2b trials. In phase ...
(Date:4/4/2019)... ... April 03, 2019 , ... ... intimate off-the-record collaboration and dialogue, today announces its Boston CEO conference to be ... into the industry’s challenges and opportunities with high-level panels and discussions from past, ...
(Date:3/27/2019)... (PRWEB) , ... March 27, 2019 , ... In honor ... raise awareness on the importance of healthy meals and good nutrition. This month, ... the Food Bank’s volunteer chef. , The first segment addressed the nutritional ...
(Date:3/23/2019)... ... March 22, 2019 , ... Tosoh Bioscience LLC ... (MALS) detector , offering a revolutionary approach for the measurement of molecular weight ... A novel optical design, a unique cell-block assembly, and a new calculation methodology ...
Breaking Biology Technology:
Cached News: