HOME >> BIOLOGY >> NEWS
Phthalates found in infants treated in NICUs that use devices containing phthalates

Boston, MA - Researchers from the Harvard School of Public Health (HSPH), two Harvard-affiliated hospitals, and the U.S. Centers for Disease Control and Prevention found that infants in neonatal intensive care units (NICUs) whose care entailed the use of medical devices containing di(2-ethylhexyl) phthalate (DEHP) had high levels of this compound in their bodies. In addition, in one of the first reports of its kind, the investigators found among the infants a direct relationship between these levels and the intensity at which DEHP-containing medical devices were used in their treatment. The findings appear in the on-line issue of Environmental Health Perspectives. (Full article)

DEHP is used to soften and plasticize the rigid polymer polyvinyl chloride (PVC). In PVC plastic, DEHP readily migrates out of the plastic into blood and fat-containing solutions in contact with the plastic, a phenomenon observed with blood stored in PVC bags. The DEHP may also migrate out of the plastic into the body from catheters and tubing used in medical treatments. The body metabolizes DEHP into mono-(2-ethylhexyl) phthalate (MEHP) which can be measured in urine and used as an indicator of the level of exposure to DEHP. In laboratory animals, MEHP has been shown to disrupt reproductive tract development and function following in-utero or early lifetime exposure.

DEHP is found in a variety of medical products and devices used in NICUs, including examination gloves, bags containing blood, plasma, intravenous (IV) fluids and tubing and other products associated with the delivery of fluids, nutrients, and air to NICU infants. The researchers assessed the use of DEHP-containing products in the care of 54 infants admitted to one of two NICUs, and examined the intensity of use of these products in relation to levels of MEHP in the infants' urine.

On average, the levels of MEHP in the infants' urine were manyfold higher than those observed in other studies of U.S.
'"/>

Contact: Kevin C. Myron
kmyron@hsph.harvard.edu
617-432-3952
Harvard School of Public Health
8-Jun-2005


Page: 1 2

Related biology news :

1. Phthalates now linked to fat, related health risks
2. Waters off Washington state only second place in world where glass sponge reefs found
3. First new multiple sclerosis gene found in 30 years
4. Obesity found to be a risk factor for multiple myeloma
5. Antibody-altering protein found in developing B cells
6. New use for a cell toxin found to inhibit survival proteins in cancer cells
7. New way to target and kill antibiotic-resistant bacteria found
8. Soil particles found to boost prions capacity to infect
9. Support for chromosomal theory of cancer found in cancers development of drug resistance
10. Massive herds of animals found to still exist in Southern Sudan
11. Origins of nervous system found in genes of sea sponge, report scientists at UC Santa Barbara

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/2/2018)... ... 2018 , ... Through this webinar, sponsored by Molecular Devices , participants ... the role of calcium kinetics in cardiac safety testing. The speakers for this event ... and Tsang Wai Lam, an assay development scientist at PPSC. , They will discuss ...
(Date:10/2/2018)... DIEGO (PRWEB) , ... October 02, 2018 , ... ... for the cancer research laboratory, ACEA Biosciences, The Cell Analysis Company , ... package designed specifically for immuno-oncology applications. Experimental design and data analysis for immune ...
(Date:10/1/2018)... ... October 01, 2018 , ... Myoscience, Inc. announced ... Executive Officer. Mr. Still will also be joining the Company’s Board of Directors. ... and diagnostics. He has extensive leadership experience in designing and implementing highly focused ...
Breaking Biology News(10 mins):
(Date:10/5/2018)... ... October 04, 2018 , ... Earthres Group, Inc., a multi-disciplinary ... company’s brand identity and better reflects its current breadth of markets and services. ... expertise and related support services to clients in seven market sectors, and currently ...
(Date:10/2/2018)... ... October 02, 2018 , ... ... week that teams have initiated validation of standards and testing of procedures for ... of Dr. Larry Kennedy, ACRES VP for Quality Management Systems and Chief Quality ...
(Date:9/27/2018)... ... September 26, 2018 , ... ... way ahead of their primary care physicians, according to a new Zeldis Research ... patients and doctors were asked about consumer adoption of fitness and health wearables, ...
(Date:9/24/2018)... ... , ... ReGrow Helmet , the most advanced laser hair treatment device, ... hair regrowth in the comfort of one’s home. Early campaign backers will save 40% ... sophisticated design and advanced technology of the ReGrow Helmet will lead the industry in ...
Breaking Biology Technology:
Cached News: