HOME >> BIOLOGY >> NEWS
Pomegranate juice slows PSA acceleration rate after prostate cancer surgery, radiation

PHILADELPHIA Pomegranate juice packs a punch on prostate cancer that prolongs post-surgery PSA doubling time, drives down cancer cell proliferation and causes prostate cancer cells to die, according to a study published in the July 1 issue of Clinical Cancer Research.

Researchers at the Jonsson Cancer Center at UCLA reported that patients with recurrent prostate cancer who drank pomegranate after surgery or radiation treatment saw their PSA blood content levels double after about 54 months. By comparison, PSA levels in the same patients prior to drinking the daily doses of eight-ounce pomegranate juice accelerated more quickly, doubling their PSA levels in only 15 months.

PSA, or prostate specific antigen, is a protein marker for prostate cancer. The faster PSA levels increase in the blood of men after treatment, the greater their potential for dying of prostate cancer.

"The velocity of the increase in PSA is decreased by 35 percent among those who drank the pomegranate juice," said Allan Pantuck, M.D., associate professor, Department of Urology, David Geffen School of Medicine, UCLA, and lead author of the paper.

"We are hoping that pomegranate juice offers a novel strategy for prolonging the doubling time in men who have been treated for prostate cancer," Dr. Pantuck added.

According to the study, sera from patients after treatment yielded a net decrease of almost 30 percent in the numbers of prostate cancer cells raised in culture. Similarly, cultured sera from these patients decreased cell proliferation by 12 percent, compared to cells grown with sera from the men taken prior to initiation of the pomegranate treatment program. In addition, treated sera induced 17 percent more programmed cell death, or apoptosis, than sera from the men prior to treatment.

Additional exploratory experiments conducted by Dr. Pantuck and his colleagues examined antioxidant characteristics of the fruit juice. '"/>

Contact: Warren Froelich
froelich@aacr.org
215-440-9300
American Association for Cancer Research
1-Jul-2006


Page: 1 2

Related biology news :

1. Pomegranate juice helps keep PSA levels stable in men with prostate cancer
2. Pomegranate juice for moms may help babies resist brain injury
3. New study suggests Concord grape juice may provide protection against breast cancer
4. 100 percent juice not associated with overweight in children
5. Cloudy apple juice four times healthier than clear
6. Pediatrics study shows no link between juice and childrens weight
7. Orange juice beverage fortified with plant sterols lowers indicators of heart disease risk
8. Fruit juice intake among preschool children not associated with weight
9. Compounds in cranberry juice show promise as alternatives to antibiotics
10. Study shows fruit and vegetable juice consumption may reduce risk of Alzheimers disease
11. UMass Lowell research shows benefits of apple juice on neurotransmitter affecting memory

Post Your Comments:
(Date:4/16/2014)... museum collections two new species of yellow-shouldered bats have been unearthed ... Field Museum of Natural History and described in the open access ... the genus Sturnira are part of a recent discovery ... third one still waiting to be officially announced. , Up until ...
(Date:4/16/2014)... Centre INRSInstitut Armand-Frappier has just received a research grant from ... nearly US$600,000. The 5-year grant is to pursue cutting-edge research ... explore their biomedical potential in the field of oncology as ... a grant at this level is an accomplishment in itself," ...
(Date:4/16/2014)... Arkin, director of the Physical Biosciences Division of Lawrence ... is recognized as a leading authority on the evolutionary ... application to systems and synthetic biology, has been named ... Lawrence Award by U.S. Energy Secretary Ernest Moniz. The ...
Breaking Biology News(10 mins):Two new species of yellow-shouldered bats endemic to the Neotropics 2High-level NIH grant goes to professor Nicolas Doucet of INRS 2Berkeley Lab's Adam Arkin wins 2013 Lawrence Award 2Berkeley Lab's Adam Arkin wins 2013 Lawrence Award 3
(Date:1/14/2014)... MA (PRWEB) January 14, 2014 iLab Solutions, ... Detwiler as the new Director of Product Strategy. In this ... well as iLab sub-teams to guide in the development of ... iLab provides the maximum possible benefit to the scientific community ...
(Date:1/14/2014)... WESTBOROUGH, Mass. , Jan. 14, 2014  RXi ... on discovering, developing and commercializing innovative therapies addressing ... announced that it received the Notice of Allowance ... on its unique self-delivering RNAi compounds (sd-rxRNA®), for ...
(Date:1/14/2014)... , Jan. 14, 2014   Kinaxis ®, provider of ... and sales and operations planning ( S&OP ) service, is ... Summit , which will be held at the Hilton San ... join Kinaxis customer Elisabeth Kaszas , Director of Supply ...
(Date:1/14/2014)... Kerr Corporation, a leading manufacturer of innovative ... information about dual arch impressions on its dental blog. ... the blog entry serves up a list of tips to ... demonstration by Dr. David Little as he crafts a porcelain ...
Breaking Biology Technology:iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
Cached News: