HOME >> BIOLOGY >> NEWS
Potential for malaria transmission higher than previously thought

Each year, malaria results in more than a million deaths. Controlling this disease involves understanding its transmission, and understanding its transmission means understanding its basic reproductive number, R0. For all infectious disease, R0 describes the most important aspects of transmission as it is the expected number of hosts that can trace their infection directly back to a single host after one disease generation. For vector-borne diseases, such as malaria, R0 is given by a classic formula. In a new study published in PLoS Biology, David Smith and colleagues demonstrate that estimates of R0 range from around one to over 3,000, providing much higher estimates than previously thought, with serious implications for the control of the disease.

The author provides 121 estimates of R0 for Plasmodium falciparum malaria in African populations. In addition to the higher estimates of R0, they also show that in small human populations, R0 approximates transmission when counting infections from mosquito to mosquito, but overestimates it from human to human. Previous studies showed that transmission is amplified if some humans are bitten more than others. The authors confirm that such heterogeneous biting amplifies transmission counting from mosquito to mosquito, but it can also dampen transmission counting from human to human. Humans who are bitten most both infect a large number of mosquitoes and absorb many infectious bites.

What does this mean for control? When R0 is in the thousands, eliminating malaria may seem impossible. If transmission from the humans who are bitten the most can be targeted, however, local elimination can still be within reach.


'"/>

Contact: Natalie Bouaravong
press@plos.org
415-568-3445
Public Library of Science
19-Feb-2007


Page: 1

Related biology news :

1. Potential genetic testing for substance abuse raises hope, concern
2. Potential new therapeutic target for asthma, allergies and cancer
3. Potential diagnostic marker indicates effectiveness of anti-angiogenic drugs
4. Potential new treatment strategy for Alzheimers disease and other brain and spinal cord damage
5. Potential vaccine developed for deadly leishmaniasis disease
6. LIAI initiatives battle influenza; Potential bird flu treatment among their findings
7. Potential malaria drug target identified
8. Potentially harmful fluoride levels found in some instant teas
9. Potential new oncogene may be missing link in cancer-causing chain
10. Edible fish feasts beats malaria
11. Identified mechanism in the malaria parasite to help it adapt to infected individuals

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/21/2019)... , ... August 20, 2019 , ... ... and commercialization of bioactive technologies for the spine, today announced the 510(K) clearance ... a unique surface modification that is proven to improve osseointegration through superior hydrophilicity ...
(Date:8/15/2019)... TORONTO (PRWEB) , ... August 15, 2019 , ... ... finally passed. Now what? As serialization mandates become increasingly complex, and aggregation becomes ... their current serialization software is the best long-term solution. , Until now, most ...
(Date:8/14/2019)... ... ... Join Jonathan Riek, PhD, VP, Musculoskeletal & Metabolic Imaging, BioTel Research ... EDT to learn about two common imaging methods in NAFLD/NASH to aid with early ... diffuse liver disease, with a worldwide prevalence of 20-46 percent. NAFLD can be subdivided ...
Breaking Biology News(10 mins):
(Date:9/17/2019)... , ... September 16, 2019 , ... ... via CNBC on Saturday, September 21st @11:00am ET. Check local listings for more ... Ltd. (Credo Biomedical), a molecular diagnostic company from Singapore dedicated to developing ...
(Date:9/11/2019)... ... September 10, 2019 , ... Catalent, the leading global provider ... and consumer health products, today announced that Alex Haig, Senior Director, Engineering will ... AG, Schwabisch Hall, Germany, on Sept. 18-19, 2019. , On Wednesday, Sept. 18 ...
(Date:9/2/2019)... , ... September 02, 2019 , ... ... and in vitro diagnostics, has launched the industry’s first epigenetics data mining services ... meaning of epigenetic data and other data types. , Next generation sequencing in ...
(Date:8/27/2019)... HOUSTON (PRWEB) , ... August 27, 2019 , ... ... chain engineering firm, is pleased to announce it has promoted Consulting Engineer, Robert ... Solutions, Battista has added the responsibility of onboarding and mentoring new engineers as ...
Breaking Biology Technology:
Cached News: