HOME >> BIOLOGY >> NEWS
'Preconditioning' helps protect brain's blood vessels from stroke

NEW YORK (July 17, 2007) -- Challenging brain tissue with a small noxious stimulus beforehand gives it a resilience that can lessen damage to blood vessels during a stroke, report researchers at Weill Cornell Medical College in New York City.

"This preconditioning works along the theory of 'what doesn't kill me makes me stronger,'" explains senior researcher Dr. Costantino Iadecola, the George C. Cotzias distinguished professor of neurology and neuroscience and Director of Neurobiology at Weill Cornell, and attending neurologist at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

"We already knew that preconditioning helps minimize damage to heart tissue -- it's a strategy cardiologists routinely use today. And we know it can help protect brain cells -- neurons -- against stroke damage," Dr. Iadecola says. "Now, besides illuminating mechanisms involved in this process, our new study in mice demonstrates that preconditioning also shields the brain's blood vessels from stroke injury," he explains.

"The hope is that by studying this natural means of self-defense, we might develop potent pharmaceutical means of either preventing stroke or minimizing stroke damage," he says.

The findings appear as a special highlighted paper in the Journal of Neuroscience.

According to the National Stroke Association, stroke is the third leading killer of Americans and the number one cause of adult disability. And yet scientists have still not developed a truly effective means of treating these attacks.

"We knew that preconditioning -- giving the brain a slight noxious stimulus beforehand -- can strengthen brain cells against damage from a larger insult later on. This phenomenon occurs naturally in the human brain," explains lead researcher Dr. Alexander Kunz of the University of Dresden, Germany. Dr. Kunz worked on the study while at Weill Cornell.

But exactly how does preconditioning work, and can it
'"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
19-Jul-2007


Page: 1 2 3

Related biology news :

1. Genetic variation helps to understand predisposition to schizophrenia
2. Link between sunspots, rain helps predict disease in east Africa
3. Taking a supplement of glycine helps prevent degenerative diseases such as arthrosis or osteoporosis
4. Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
5. Nanotechnology helps scientists make bendy sensors for hydrogen vehicles
6. Manchester University helps with pharaoh DNA analysis
7. A spoonful of sugar helps your waistline go down
8. Study helps preserve Arctic whale, Eskimo subsistence hunt
9. Ethanol injection helps manage bone metastasis in thyroid cancer patients
10. Fusing imaging technologies creates synergy, helps diagnose heart disease accurately
11. Stuck on you: CEACAM6 helps E. coli stick to intestinal lining in Crohns disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/29/2020)... ... January 29, 2020 , ... Jason Burke ... Data Sciences practice, providing consulting services for strategy, research and development and data ... Townley, co-founder and Managing Partner of CREO, an innovative management consulting and advisory ...
(Date:1/29/2020)... ... January 29, 2020 , ... VGXI, a world leading contract ... DNA vaccine against the novel coronavirus (2019-nCoV) that has recently emerged in Wuhan, ... $9 million from the Coalition for Epidemic Preparedness Innovations (CEPI) will fund the ...
(Date:1/28/2020)... (PRWEB) , ... January 28, 2020 , ... ... ’s methods improve care efficiency, reduce total cost of care, and limit the ... a large healthcare provider group headquartered in San Antonio, Texas specializes in improving ...
Breaking Biology News(10 mins):
(Date:1/28/2020)... Pa. (PRWEB) , ... January 28, 2020 , ... ... of Better Salivary Assay Kits . The new Salivary Total Human ... research. “By measuring total immunoglobulin G in saliva, researchers can extend the accuracy ...
(Date:1/24/2020)... ... January 24, 2020 , ... The plastic and reconstructive surgeons at ... New Jersey epitomize the notion that plastic surgery is much more than just cosmetic ... media. , Over the last 20 years NJ Top Docs, Dr. Andrew Elkwood, Dr. ...
(Date:1/23/2020)... DALLAS (PRWEB) , ... January 22, 2020 , ... ... presented new developments in the cosmetic surgery industry at two recent North American ... Canadian investors at the Canaccord Genuity Medical Technologies & Diagnostics Forum on November ...
(Date:1/22/2020)... , ... January 21, 2020 , ... ... with the precision of Genome editing. The partners have agreed to co-develop and ... of CRISPR research, agricultural, and pre-clinical programs. Over the longer-term, the parties aim ...
Breaking Biology Technology:
Cached News: